Strain Information | |
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Image | |
BRC No. | RBRC-KIT0028 |
Type | Chemically-induced Mutation |
Species | Mus musculus |
Strain name | KITOX-BM15-Mu |
Former Common name | |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Chang-Woo Song and Jae-Woo Cho, Korea Institute of Toxicology in Korea Research Institute of Chemical Technology. Mutant mice were crossed to BALB/c. |
Strain description | Homozygous mutant mice resemble hairless rhino mice in which no hair regeneration occurs and skin tissue is extensively folded. A mutation in the human homolog of Hr (HR; OMIM602302) , are known to cause congenital hairless disease, alopecia universalis congenita (OMIM602302). The Depositors are welcome to collaborate further detailed analyses on this mutant mouse. Series of other ENU-mutant mice with interesting phenotypes have also been deposited to RIKEN BRC. |
Colony maintenance | Heterozygote (male) x Homozygote (female) Homozygous mutant females have nurturing young, possibly as a result of defects in lactation. |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter |
Ordering Information | |
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Donor DNA | |
Research application | |
Specific Term and Conditions | The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. Prior to filing for a patent, or intellectual property or other rights based on results of research using the BIOLOGICAL RESOURCE, the RECIPIENT shall acquire the consent from the DEPOSITOR for such application. Use of the BIOLOGICAL RESOURCE shall be limited to a collaborative research. And Use of the BIOLOGICAL RESOURCE shall require co-authorship of the DEPOSITOR for TWO years after deposition of the BIOLOGICAL RESOURCE to the RIKEN BRC or for the first publication if no publication is made within the TWO years. |
Depositor | Chang-Woo Song (Korea Institute of Toxicology in Korea Research Institute of Chemical Tech) |
Strain Status | Frozen embryos |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved embryos (within 1 month) |
Additional Info. | Mouse of the Month Apr 2005 Necessary documents for ordering:
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BRC mice in Publications |
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No Data |