Strain Data Sheet
RBRC04904
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC04904 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | B6;129P2-Cxcr4<tm1Yiw> |
| Former Common name | B6.129P2-Cxcr4<tm1Yiw> |
| H-2 Haplotype | |
| ES Cell line | E14.1 [129P2/OlaHsd] |
| Background strain | |
| Appearance | |
| Strain development | Developed by Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo in 2010. The mice were backcrossed to C57BL/6 for at least 10 times. |
| Strain description | Cxcr4 floxed mice. Systemic null knockout mice are embryonic lethal. |
| Colony maintenance | |
| References | Arthritis Res. Ther., 12, R188 (2010). 20939892 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |
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| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP1loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP1loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)1neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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| Donor DNA | P1 phage loxP sites, mouse Phosphoglycerate kinase (PGK) promoter, E. coli neomycin resistance gene, mouse Cxcr4 genomic DNA |
| Research application | |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Arthritis Res. Ther., 12, R188 (2010). Please obtain the written consent from Professor Yoichiro Iwakura (iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science) for the use. |
| Depositor | Yoichiro Iwakura (The University of Tokyo) |
| Strain Status |  Frozen sperm |
| Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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| No Data |