Strain Information | |
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Image | |
BRC No. | RBRC10771 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.B6CB-Rr45<tm1.1Tshir> Rr(MRCS1)<tm1.1Tshir>/Ms |
Former Common name | MRCS1-MFCS4 double knockout (DKO), delta MRCS1; delta MFCS4, MRCS1-/-; MFCS4-/- |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | |
Appearance | |
Strain development | Developed by Toshihiko Shiroishi and Tomoko Sagai, National Institute of Genetics in 2013 using TT2 ES cells. C57BL/6 congenic line. |
Strain description | Deletion mutant of MRCS1 and MFCS4 enhancer of Shh gene. |
Colony maintenance | |
References | Development, 136(10):1665-74 (2009). 19369396 Sci. Rep., 7(1):13004 (2017). 29021530 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter 9530036O11RikRIKEN cDNA 9530036O11Rik59530036O11Rik<tm1.1Tshir>targeted mutation 1.1, Toshihiko Shiroishi Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter |
Ordering Information | |
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Donor DNA | mouse PGK promoter, E.coli Neomycin resistant gene, bovine poly A signal, P1 phage loxP |
Research application | Cre/loxP system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Sci Rep. (2017) 7:13004. Development. (2009)136:1665-74. |
Depositor | Toshihiko Shiroishi (National Institute of Genetics) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |