Strain Information | |
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Image | |
BRC No. | RBRC10789 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6N-Ttr<tm1.1(NLS/cre)Card> |
Former Common name | Ttr-Cre |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Michihiko Sugimoto and Kimi Araki at Card, Kumamoto University in 2017. 6NK-7 ES cells derived from C57BL/6N were used to generate this strain. C57BL/6N genetic background. |
Strain description | Knockin mice in which NLS-Cre replaced the coding sequence for the Ttr gene. |
Colony maintenance | |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Ttrtransthyretin18Ttr<tm1.1(NLS/cre)Card>targeted mutation 1.1, Center for Animal Resources & Development Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter En2En2 SA (mouse En2 intron 2/exon 3 splice acceptor sequence)18En2 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter HBB2rabbit beta-globin intron18HBB2 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter crePhage P1 Cre recombinase18cre Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP18loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter nlsSV40 large T antigen nuclear localization signal (NLS)18nls |
Ordering Information | |
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Donor DNA | SV40 large T antigen nuclear localization signal (NLS), Rabbit beta-globin intron, mouse En-2 intron/exron splicing acceptor, Phage P1 Cre, mouse Pgk polyA signal, Phage P1 loxP site, mouse Ttr genomic DNA |
Research application | Cre/loxP system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. 本系統を用いて公表された第一報の論文In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent form the DEPOSITOR. |
Depositor | Kimi Araki (Kumamoto University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |