Strain Information | |
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Image | |
BRC No. | RBRC10904 |
Type | Transgene |
Species | Mus musculus |
Strain name | 129.Cg-Tg(Th-MYCN)41WawKkad |
Former Common name | Th-MYCN, TH-MYCN |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Deposited by Welliam A. Weiss in 2020. |
Strain description | The rat tyrosine hydrolase promoter directs expression of human v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) (MYCN) to migrating cells of the neural crest during early development. |
Colony maintenance | |
References | EMBO J., 16(11):2985-95 (1997). 9214616 |
Health Report | |
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Examination Date / Room / Rack | 2024/02/26Room:4-CRack:K 2023/11/27Room:4-CRack:K 2023/08/28Room:4-CRack:K 2023/05/29Room:4-CRack:K 2023/02/27Room:4-CRack:K 2022/11/29Room:4-CRack:K 2022/08/29Room:4-CRack:K 2022/05/31Room:4-CRack:K |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter HBB2rabbit beta-globin Intron (enhancer)UNHBB2 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter MYCNHuman MYCN cDNAUNMYCNrat tyrosine hydroxylase (TH) promoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Herpes simplex virus Thymidine kinase gene terminator/poly(A) sequenceUN |
Ordering Information | |
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Donor DNA | Rat Tyrosine Hydroxylase Promoter, Rabbit Beta-Globin Intron (enhancer), Human MYCN cDNA, Herpes simplex virus Thymidine kinase gene terminator/poly(A) sequence |
Research application | Cancer Research |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. EMBO J. 1997 Jun 2;16(11):2985-95Limitation of recipients of the BIOLOGICAL RESOURCE to not-for-profit institutions, limitation of the use to academic research purposes for-profit institutions or use for commercial research purposesshall acquire a prior written consent from the Depositor. |
Depositor | William Weiss (The University of California, San Francisco) |
Strain Status | Live mice Frozen embryos Frozen sperm |
Strain Availability | Cryopreserved embryos (within 1 month) Live mouse (1 to 3 months) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |