Strain Information | |
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Image | |
BRC No. | RBRC10942 |
Type | CRISPR/Cas9 |
Species | Mus musculus |
Strain name | C57BL/6J-Trps1<em1Osud> |
Former Common name | Trps1 Enhancer1 knockout mouse |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Deposited by Makoto Abe, Osaka University in 2019. This strain was generated by the Advanced Animal model Support. Mutant shows mild scoliosis. |
Strain description | Mutant mice lacking about 3 kb genomic fragment upstream the Trps1 gene. |
Colony maintenance | |
References |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Trps1transcriptional repressor GATA binding 115Trps1<em1Osud>endonuclease-mediated mutation 1, Makoto Abe |
Ordering Information | |
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Donor DNA | [Streptococcus Pyogenes Cas9*, Simian Virus SV40 NLS, Porcine teschovirus 2A peptide sequence, Streptomyces alboniger puromycin resistance gene*, Bos taurus bGH polyA, E. coli ampicilin resistance gene, human U6 promoter, CMV enhancer, Streptococcus Pyogenes trscrRNA, mouse gRNA sequence]* Not detected by PCR using Marker Gene Detection kit (TOYOBO, Osaka, Japan). Other introduced genes were not tested. |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (will be announced.) RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. |
Depositor | Makoto Abe (Osaka University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |