Strain Data Sheet
RBRC11115
Strain Information | |
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| Image | |
| BRC No. | RBRC11115 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | B6;129P2-Rest<tm1Ymat> |
| Former Common name | Rest-KO |
| H-2 Haplotype | |
| ES Cell line | E14.1 [129P2/OlaHsd] |
| Background strain | |
| Appearance | |
| Strain development | Developed by Yasuhisa Matsui, Tohoku University, in 2012. Mice were generated using E14-1 ES cells derived from 129P2/OlaHsd. Mixed genetic background with C57BL/6. |
| Strain description | Rest knockout mice. Exon 1 was replaced with a pgk-neo cassette in the inverse orientation via homologous recombination. |
| Colony maintenance | |
| References | Dev. Biol., 372(2):190-202 (2012). 23022299 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |
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| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP5loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP5loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)5mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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| Donor DNA | phage P1 loxP sites, mouse phosphoglycerate kinase promo (Pgk1 promoter), E. coli neomycin resistant gene, polyA付加配列 |
| Research application | Cre/loxP system |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Dev Biol. 2012 Dec 15;372(2):190-202. |
| Depositor | Yasuhisa Matsui (Tohoku University) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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| No Data |