Strain Information | |
---|---|
Image | |
BRC No. | RBRC11138 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.Cg-Blnk<tm1Dkit> Ptprc<a> |
Former Common name | BLNK(BASH or SLP65) knockout mouse |
H-2 Haplotype | |
ES Cell line | Bruce 4 [B6.Cg-Thy1<a>] |
Background strain | |
Appearance | |
Strain development | Deposited by Daisuke Kitamura, Tokyo University of Science in 2020. Mice were generated using Bruce 4 ES cells derived from B6.Cg-Thy1.1. C57BL/6 congenic line. |
Strain description | C57BL/6 congenic Blnk mutant mice with Ly5.1. |
Colony maintenance | |
References | Proc. Natl. Acad. Sci. USA, 97(6):2755-60 (2020). 10688901 Immunity, 18(6):825-36 (2003). 12818163 |
Health Report | |
---|---|
Examination Date / Room / Rack | 2024/02/05Room:2-検Rack:G 2023/11/06Room:2-検Rack:G 2023/08/07Room:2-検Rack:G 2023/05/08Room:2-検Rack:G 2023/02/06Room:2-検Rack:G 2022/11/07Room:2-検Rack:G 2022/08/08Room:2-検Rack:G 2022/05/09Room:2-検Rack:G |
Gene | |
---|---|
Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Ptprcprotein tyrosine phosphatase, receptor type, C1Ptprc<a>a variantB220, CD45, Cd45, CD45R, Ly-5, LY-5, Lyt-4, T200 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter BlnkB-cell linker19Blnk<tm1Dkit>targeted mutation 1, Daisuke KitamuraBASH, Bca, BCA, BLNK, Ly57, Ly-57, SLP-65 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP19loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP19loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)19mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
---|---|
Donor DNA | SV40 PolyA signal, P1 phage loxP sites, mouse PGK gene promoter, E.coli Neomycin resistant gene, mouse Pgk1 PolyA signal, Mouse Blnk genomic DNA |
Research application | Cre/loxP system Immunology and Inflammation Research |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Immunity, 18(6):825-36 (2003).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
Depositor | Daisuke Kitamura (Tokyo University of Science) |
Strain Status | Live mice Frozen embryos Frozen sperm |
Strain Availability | Cryopreserved embryos (within 1 month) Live mouse (3 to 6 months) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
---|
No Data |