Strain Information | |
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Image | |
BRC No. | RBRC11139 |
Type | Targeted Mutation Congenic |
Species | Mus musculus |
Strain name | B6.Cg-Dnase1l3<tm1Dkit> |
Former Common name | DNase1L3 (DNaseγ) knockout mouse |
H-2 Haplotype | |
ES Cell line | Bruce 4 [B6.Cg-Thy1<a>] |
Background strain | |
Appearance | |
Strain development | Deposited by Daisuke Kitamura, Tokyo University of Science in 2020. Mice were generated using Bruce 4 ES cells derived from B6.Cg-Thy1.1. C57BL/6 congenic line. |
Strain description | Dnase1l3 mutant mice. A neo fragment was inserted at the exon 5 of the Dnase1l3 gene. |
Colony maintenance | |
References | Biochem. Biophys. Res. Commun., 27;516(3):790-795 (2019). 31255286 PLoS One, 8(12):e80223 (2013). 24312463 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP14loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP14loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)14mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
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Donor DNA | P1 phage loxP sites, mouse phosphoglycerate kinase promoter (PGK promoter), E.coli Neomycin resistant gene, Mouse Pgk1 PolyA signal, Mouse DNase1l3 genomic DNA |
Research application | Cre/loxP system Immunology and Inflammation Research |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. PLoS One, 8(12):e80223 (2013).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
Depositor | Daisuke Kitamura (Tokyo University of Science) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |