Strain Information | |
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Image | |
BRC No. | RBRC11140 |
Type | Targeted Mutation Congenic |
Species | Mus musculus |
Strain name | B6.Cg-Dnase1l3<tm1Dkit> Dffb<tm1Osa> |
Former Common name | CAD-/-DNase1L3-/- double knockout mouse |
H-2 Haplotype | |
ES Cell line | Bruce 4 [B6.Cg-Thy1<a>] |
Background strain | |
Appearance | |
Strain development | Deposited by Daisuke Kitamura, Tokyo University of Science in 2020. |
Strain description | Double mutant of the Dnase1l3 and Dffb. |
Colony maintenance | |
References | Nat. Immunol., 4, 138-144 (2003). 12524536 PLoS One, 8(12):e80223 (2013). 24312463 Biochem. Biophys. Res. Commun., 516, 790-795 (2019). 31255286 |
Health Report | |
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Examination Date / Room / Rack | 2024/03/11Room:3-2Rack:A 2023/12/11Room:3-2Rack:A 2023/09/11Room:3-2Rack:A 2023/06/26Room:3-2Rack:A 2023/06/13Room:3-2Rack:A 2023/03/13Room:3-2Rack:A 2022/12/12Room:3-2Rack:A 2022/09/12Room:3-2Rack:A 2022/06/13Room:3-2Rack:A |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP14loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP14loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)14mouse phosphoglycerate kinase promoter (PGK promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter DffbDNA fragmentation factor, beta subunit4Dffb<tm1Osa>targeted mutation 1, Shigekazu Nagata40kDa, 5730477D02Rik, caspase-activated DNase, CPAN, DFF40, Didff Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)4neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Ordering Information | |
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Donor DNA | P1 phage loxP sites, mouse phosphoglycerate kinase promoter (PGK promoter), E.coli Neomycin resistant gene, Mouse Pgk1 PolyA signal, Mouse DNase1l3 genomic DNA, Herpes simplex virus Thymidine kinase gene promoter, Mouse Dffb genomic DNA |
Research application | Cre/loxP system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Biochem. Biophys. Res. Commun., 516, 790-795 (2019). Nat. Immunol., 4, 138-144 (2003).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. RECIPIENT may only use the BIOLOGICAL RESOURCE for non-commercial academic research purpose. The RECIPIENT should negotiate with the DEPOSITOR in the case of application for any patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Daisuke Kitamura (Tokyo University of Science) |
Strain Status | Live mice Frozen embryos Frozen sperm |
Strain Availability | Cryopreserved sperm (within 1 month) Live mouse (1 to 3 months) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |