Strain Information | |
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Image | |
BRC No. | RBRC11258 |
Type | CRISPR/Cas9 |
Species | Mus musculus |
Strain name | B6D2-Tmem168<em1(R539Q)Osb> |
Former Common name | Tmem168<R539Q/wt> |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Deposited by Masahito Ikawa, Research Institute for Microbial Diseases, Osaka University in 2020. Fertilized eggs derived from BDF1 × BDF1 were used to generate this line. Mixed genetic background. |
Strain description | Tmem168 mutant (R539Q) mouse generated by the CRISPR/Cas9. 1,291 bp deletion and 11 bp deletion in the Tmem249 gene. |
Colony maintenance | |
References | FASEB J., 34(5):6399-6417 (2020). doi: 10.1096/fj.201902991R. Epub 2020 Mar 16 32175648 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Tmem168transmembrane protein 1686Tmem168<em1(R539Q)Osb>endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University |
Ordering Information | |
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Donor DNA | Streptococcus pyogenes crRNA, tracrRNA, Mouse a part of Tmem168 gene |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. FASEB J. 2020 May;34(5):6399-6417. doi: 10.1096/fj.201902991R. Epub 2020 Mar 16RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again. |
Depositor | Masahito Ikawa (Osaka University) |
Strain Status | Frozen sperm |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |