Strain Information | |
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Image | |
BRC No. | RBRC11278 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6N-Pkn2<tm1.1Hmuk> |
Former Common name | PKN2<flox/flox> |
H-2 Haplotype | |
ES Cell line | RENKA [C57BL/6NCrlCrlj] |
Background strain | |
Appearance | |
Strain development | established in 2009. back-crossed to C57BL/6N (Charles River) more than 10 times. |
Strain description | Exons 18 and 19 of PKN2, encoding the area around the activation loop of the catalytic domain of this enzyme, are flanked by two loxP sequences in the same orientation. |
Colony maintenance | |
References | Genes Cells, 22(2):220-236 (2017). doi: 10.1111/gtc.12470. Epub 2017 Jan 19. 28102564 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site3Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP3loxP |
Ordering Information | |
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Donor DNA | phage P1 loxP sites, yeast FRT (flippase recombination target) site, mouse Pkn2 genomic DNA |
Research application | Cre/loxP system FLP/frt system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genes Cells. 2017 Feb;22(2):220-236. doi: 10.1111/gtc.12470. Epub 2017 Jan 19.Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using e-mail. |
Depositor | Hideyuki Mukai (Kobe University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |