Dear colleagues, RIKEN BRC participates the CREATE Consortium as an advisor, the International Coordination Group. The CREATE is collecting requests and suggestions from the international mouse research community for new Cre lines. Please read the following letter. ======================================================================== Dear Scientist, If you are using or planning to use mouse conditional mutagenesis (Cre-LoxP system) as a tool in your experiments, we encourage you to read this. CREATE is an international Coordination Action addressing a large scale data gathering activity for systematic conditional mouse mutagenesis. As part of the CREATE mandate, we want to determine the tools you need. Therefore we invite you to participate in an on-line survey at our new website, www.creline.org <http://www.creline.org/> . Your responses to this survey will help us to identify tissues, cell lineages and biological fields for which there are insufficient or ineffective Cre drivers. These will form the basis for selection of >250 new Cre driver mouse lines that will be generated by the EU consortium EUCOMMTOOLS to be distributed worldwide through the European Mutant Mouse Archive (EMMA) and by the Canadian NorCOMM2ls Project to be distributed by the Canadian Mouse Mutant Repository (CMMR). The results of the survey as well as production status of the new Cre lines will be available at CREATE website - www.creline.org <http://www.creline.org/> . We would be very grateful if you forwarded this link to your colleagues (especially students and postdocs) who for logistical reasons might not be on the mailing list. We will collect and consider all responses received prior to 25 September 2010. The survey is anonymous, however if you would like to receive direct feedback you may provide your contact e-mail in an allocated field of the survey. Thank you for your time and advice, and don't hesitate to contact us with further questions or ideas. Nadia Rosenthal for the CREATE consortium EMBL Mouse Biology Unit European Molecular Biology Laboratory via Ramarini 32 00015 Monterotondo (RM) ITALY e-mail: rosenthal@embl.it web: www.embl.it <http://www.embl.it/> The CREATE consortium: Nadia Rosenthal, EMBL-MR (Italy) (Coordinator) Vassilis Aidinis, BSRC Fleming (Greece) Steve Brown, MRC-MGU (UK) Janan Eppig, JAX (USA) Yann Herault, GIE-CERBM (France) Andras Nagy, SLRI-MSH (Canada) Ramiro Ramirez-Solis, Sanger (UK) Damian Smedley, EMBL-EBI (UK) Wolfgang Wurst, IDG-HMGU (Germany) ======================================================================== Thank you. Atsushi Yoshiki, Ph.D. Head Experimental Animal Division RIKEN BioResource Center Tsukuba, Ibaraki 305-0074 Japan Tel: +81-29-836-9192 FAX:+81-29-836-9190 ________________________________________________________________________ 2010.09.10