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Cryopreservation of Mouse Embryos by Ethylene Glycol-Based Vitrification
JoVE 3155 11/18/2011

RIKEN BioResource Center Mouse E-mail Message No. 99

RIKEN BioResource Center (BRC) is pleased to update you with the latest

======= Contents =======================================================
- Special topic: Mouse of the Month 
"Visualizing primordial germ cell development in mice"
- Discovery of novel Gumby functions from RIKEN mutant mouse library
- Announcement: The 72nd Annual Meeting of the Japanese Cancer 
- User publications

|  Special topic: Mouse of the Month    August 2013

Visualizing primordial germ cell development in mice 
  RBRC05382  B6.Cg-Tg(Dppa3-ECFP)#Sait/Rbrc
  RBRC05383  B6;B6D2-Tg(Prdm1-Venus)#Sait/Rbrc
  RBRC05384  B6;B6D2-Tg(Prdm14-Venus)1Sait/SaitRbrc
  RBRC05385  B6;B6D2-Tg(Dppa3-cre/Esr1*)9Sait/SaitRbrc 
  Depositor: Mitinori Saitou, M.D., Ph.D.
             Graduate School of Medicine, Kyoto University

Mouse of the Month archive

|  Discovery of novel Gumby functions from RIKEN mutant mouse library

A significant scientific contribution of the RIKEN BRC resource was just
published in Nature as an Article on June 20, 2013 [1].
In this paper, Dr. Sabine.P. Cordes of Mount Sinai Hospital in Canada 
and her colleagues reported the novel Gumby (Fam105b) functions from 
various aspects. Drs.Yoichi Gondo and Ryutaro Fukumura of Mutagenesis 
and Genomics Team, RIKEN BRC developed and provided the key resource of 
mutant mouse strains each carried a single point mutation in the Gumby 
gene from the RIKEN mutant mouse library.

[1] E. Rivkin, et al. The linear ubiquitin-specific deubiquitinase 
gumby regulates angiogenesis. Nature 498, 318-324, 2013

|  Announcement: The 72nd Annual Meeting of the Japanese Cancer 
|  Association

  The 72nd Annual Meeting of the Japanese Cancer Association will be
held at Pacifico Yokohama from October 3rd to the 5th. It is our
pleasure to invite you to visit our booth in the Exhibition Hall A and B.

  The 72nd Annual Meeting of the Japanese Cancer Association

|  User publications

  The following results have been newly reported by users. We are
honored to introduce new publications to the science community.
Therefore, we look forward to receiving your publications too.

RBRC00806  GFP-LC3#53
Hoshino A, Mita Y, Okawa Y, Ariyoshi M, Iwai-Kanai E, Ueyama T, Ikeda K,
Ogata T, Matoba S. Cytosolic p53 inhibits Parkin-mediated mitophagy and 
promotes mitochondrial dysfunction in the mouse heart. 
Nat Commun.;4:2308, doi: 10.1038/ncomms3308, 2013.

RBRC00806  GFP-LC3#53
RBRC03743  B6D2-Tg(CAG/Su9-DsRed2,Acr3-EGFP)RBGS002Osb
Luo SM, Ge ZJ, Wang ZW, Jiang ZZ, Wang ZB, Ouyang YC, Hou Y, Schatten H,
Sun QY. Unique insights into maternal mitochondrial inheritance in mice.
Proc Natl Acad Sci U S A.;110(32):13038-43. doi: 10.1073/pnas.1303231110,

RBRC00858  IRF-3 Knockout mice, C57BL/6J
Ysebrant de Lendonck L, Tonon S, Nguyen M, Vandevenne P, Welsby I, 
Martinet V, Molle C, Charbonnier LM, Leo O, Goriely S. Interferon 
regulatory factor 3 controls interleukin-17 expression in CD8 T 
lymphocytes. Proc Natl Acad Sci U S A.;110(34):E3189-97, 
doi: 10.1073/pnas.1219221110, 2013.

RBRC00984  ICR;129P2-Nfe2l2<tm1Mym>/MymRbrc
Ramkissoon A, Wells PG. Developmental role of nuclear factor-E2-related 
factor 2 (Nrf2) mitigating methamphetamine fetal toxicity and postnatal 
neurodevelopmental deficits. Free Radic Biol Med., 
pii: S0891-5849(13)00396-1. doi: 10.1016/j.freeradbiomed.2013.07.043, 

RBRC01420  IRF-7 knockout mice, C57BL/6J
Wang XA, Zhang R, Zhang S, Deng S, Jiang D, Zhong J, Yang L, Wang T, 
Hong S, Guo S, She ZG, Zhang XD, Li H. Interferon regulatory factor 7 
deficiency prevents diet-induced obesity and insulin resistance. Am J 
Physiol Endocrinol Metab.;305(4):E485-95, 
doi: 10.1152/ajpendo.00505.2012, 2013.

RBRC01813  GluRε1 KO mouse
RBRC01814  GluRε2 KO mouse
RBRC01840  GluRε4 KO mouse
Tomiyama K, Kato R, Hara Y, Kobayashi M, Mishina M, Yanagawa Y, M, 
Kinsella A, Koshikawa N, Waddington J L. Phenotypic characterisation of 
orofacial movement topography in mutants with disruption of amino acid 
mechanisms: glutamate N2A/B/D [GluRε1/2/4] subtypes and the GABA 
synthesising enzyme GAD65. Neuroscience, pii: S0306-4522(13)00620-9. 
doi: 10.1016/j.neuroscience.2013.07.038, 2013.

RBRC01869  Card15 KO
Zong J, Salim M, Zhou H, Bian ZY, Dai J, Yuan Y, Deng W, Zhang JY, 
Zhang R, Wu QQ, Tang QZ. NOD2 deletion promotes cardiac hypertrophy and 
fibrosis induced by pressure overload. Lab Invest., 
doi: 10.1038/labinvest.2013.99, 2013.

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