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RIKEN BioResource Center Mouse E-mail Message No. 103

RIKEN BioResource Center (BRC) is pleased to update you with the latest

======= Contents =======================================================
- Special topic: Mouse of the Month
  "New reporter line for optogenetic stimulation at high frequencies"
- User publications
- Newly deposited mouse strains
- Newly available mouse strains
- Mouse strains for freeze preservation


|  Special topic: Mouse of the Month    December 2013

New reporter line for optogenetic stimulation at high frequencies
  RBRC05843  B6.Cg-Actb<tm1(tetO-ChR2*E123T/T159C)Ahky>/AhkyRbrc

  Depositor: Akihiro Yamanaka, Ph.D.
              Research Institute of Environmental Medicine, Nagoya

Mouse of the Month archive

|  User publications

  The following results have been newly reported by users. We are
honored to introduce new publications to the science community.
Therefore, we look forward to receiving your publications too.

RBRC01774  mDomino knockout mouse
Chevillard-Briet M, Quaranta M, Grézy A, Mattera L, Courilleau C,
Philippe M, Mercier P, Corpet D, Lough J, Ueda T, Fukunaga R, Trouche D,
Escaffit F. Interplay between chromatin modifying enzymes controls colon
cancer progression through Wnt signaling. Hum Mol Genet, 2013.

RBRC02142  C57BL/6-Pdcd1-/- mouse
Horne-Debets JM, Faleiro R, Karunarathne DS, Liu XQ, Lineburg KE,
Poh CM, Grotenbreg GM, Hill GR, Macdonald KP, Good MF, Renia L, Ahmed R,
Sharpe AH, Wykes MN.
PD-1 Dependent Exhaustion of CD8+ T Cells Drives Chronic Malaria.
Cell Rep. pii: S2211-1247(13)00650-5, doi: 10.1016/j.celrep.2013.11.002,

RBRC02298  C.Cg-Il3<tm1Glli>
Leyva-Castillo JM, Hener P, Michea P, Karasuyama H, Chan S, Soumelis V,
Li M. Skin thymic stromal lymphopoietin initiates Th2 responses through
an orchestrated immune cascade. Nat Commun.; 4:2847,
doi: 10.1038/ncomms3847, 2013.

RBRC02975  B6.129S-Atg5<tm1Myok>
Rosenfeldt MT, O'Prey J, Morton JP, Nixon C, Mackay G, Mrowinska A,
Au A, Rai TS, Zheng L, Ridgway R, Adams PD, Anderson KI, Gottlieb E,
Sansom OJ, Ryan KM. p53 status determines the role of autophagy in
pancreatic tumour development. Nature, doi: 10.1038/nature12865, 2013.

|  Newly deposited mouse strains

  The following mice have been newly deposited with RIKEN BRC and will
be available shortly after rederivation.
  We appreciate the contributions of the depositors to the science

  Dr. Naojiro Minami, Kyoto University
    RBRC06132  C57BL/6-Tg(Oog1*2.7-AcGFP)B
    RBRC06133  C57BL/6-Tg(Oog1*3.9-AcGFP)A
    RBRC06134  C57BL/6-Tg(Oog1*3.9-AcGFP)B

  Dr. Yoshibumi Matsushima, Saitama Cancer Center
    RBRC06175  B6;KOR1-Mpzl3<+/->
    RBRC06176  C;KOR1-Mpzl3<+/->
    RBRC06177  KOR1-Mpzl3<-/->
    RBRC06178  B6;KOR1-Pitx3<+/->
    RBRC06179  C.KOR1-Pitx3<+/->
    RBRC06180  KOR1-Pitx3<-/->

  Dr. Takashi Kasukabe, Saitama Cancer Center
    RBRC06183  SL/Stm

  Dr. Naohiro Hashimoto, National Institute for Longevity Sciences
    RBRC06189  B6.Cg-Tg(CAG-MSTN*C313Y)
    RBRC06190  D2;129-Myod1<tm1Jae>
    RBRC06191  B6.129-Acsbg1<tm1Nah>
    RBRC06192  B6.129-Trib3<tm1Nah>
    RBRC06193  B6.Cg-Tg(Pax7-eGFP)13Nah

|  Newly available mouse strains

  The following mice have recently been rederived into our barrier
facility and are now available for distribution.

    RBRC05281  LtbR (Acc. No. CDB0531K)
    RBRC05642  B6.129-Hspa5<tm1Aoe>
    RBRC05701  STOCK Tg(FLEXCAG-VSFP-Butterfly)552Bsi
    RBRC05702  C57BL/6J-Tg(CAG-XBP1/luc)23Tiw
    RBRC05703  B6;129S4-Gt(ROSA)26Sor<tm1.1Tiw>
    RBRC05753  B6.129S4-Map3k5<tm1Hijo>
    RBRC05756  B6.Cg-Spry2<tm1Ayos>
    RBRC05761  B6.Cg-Rftn1<tm1Ayos>
    RBRC05825  C57BL/6J-Tg(hSMA-NCX1.3*del)2
    RBRC05826  C57BL/6J-Tg(hSMA-NCX1.3*SA)1
    RBRC05832  C57BL/6J-Tg(Myh6-PIP5K alpha)2
    RBRC05889  B6.129P2-Dpysl2<tm1Gosh>
    RBRC05926  B6.Cg-Map3k5<tm1Hijo> Map3k6<tm1Hijo>
    RBRC05939  B6.Cg-Tg(Mt1-RET)304Ina Hr<hr>
    RBRC05949  B6.129P2-Rbm3<tm1Ttg>
    RBRC05954  B6.129S7-Dp(7Herc2-Mkrn3)1Taku
    RBRC05975  B6.Cg-Tg(Mt1-RET)242Ina Hr<hr>

|  Mouse strains for freeze preservation

  Since a sufficient number of frozen stocks have been preserved, live
mice of the following strains will be discontinued soon.
  It will take more than 3 months to recover live mice from frozen stock.
Therefore, please inform us as soon as possible if you plan to use the
mice and request them alive.

    RBRC04023  B6C3-Senp2<Gt(venusTrap_fJAV0002-D)4004-321>
    RBRC04604  STOCK Tg(Kcnc1-EYFP)27Bsi
    RBRC05224  ICR;B6D2-Tg(CAG-Luc,Hsd17b3/EGFP)2Tysn
    RBRC05363  STOCK Tg(FLEXCAG-VSFP2.3)511Bsi
    RBRC05562  B6.Cg-Tg(Crx-rtTA)G2Tfur
    RBRC05660  B6.B6D2-Tg(CAG-CAT,SpH)5Yyan
    RBRC05755  C57BL/6-Map3k15<tm1Hijo>
    RBRC05770  B6.Cg-Tg(Pvalb-tTA)1Kftnk
    RBRC05822  C57BL/6J-Tg(hSMA-NCX1*trun)1
    RBRC05823  C57BL/6J-Tg(hSMA-NCX1DN*trun)2

*We hope you find the contents of this message of interest.
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*If you have any questions or comments, please send an e-mail to

*Content is subject to change without notice.

*All Rights Reserved.

RIKEN BioResource Center
Experimental Animal Division
3-1-1 Koyadai, Tsukuba-shi
Ibaraki, 305-0074 Japan

partially revised. (2013.12.25)