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RIKEN BioResource Center Mouse E-mail News No. 106

RIKEN BioResource Center (BRC) is pleased to update you with the latest

======= Contents =======================================================
- Special topic: Mouse of the Month "Novel ROSA26 Cre-reporter knock-in
  C57BL/6N mice"
- Modification of the terms and conditions for use of the Fucci mice
- Announcement: Japanese Conference for Laboratory Animal Science and
  Technology, Sapporo 2014
- User publications
- Newly deposited mouse strains
- Newly available mouse strains
- Mouse strains for freeze preservation

|  Special topic: Mouse of the Month    March 2014

Novel ROSA26 Cre-reporter knock-in C57BL/6N mice
  RBRC04874  C57BL/6N-Gt(ROSA)26Sor<tm1(CAG-EGFP,tdsRed)Utr>/Rbrc

  Depositor: RIKEN BioResource Center

Mouse of the Month archive

|  Modification of the terms and conditions for use of the Fucci mice

  By courtesy of Amalgaam (MBL), the Depositor of the Fucci mice, from
March 7, 2014, the Fucci mice can be distributed to academic researches
in not-for-profit entities without prior conclusion of the MTA with
Amalgam (MBL). Only the conclusion of MTA between a user and RIKEN BRC
is required. We sincerely appreciate Amalgam (MBL) for its generous
measure for users of the Fucci mice.

Fucci mice:
  RBRC02706: B6.Cg-Tg (FucciS/G2/M) #504Bsi
  RBRC02707: B6.Cg-Tg (FucciG1) #596Bsi
  RBRC02892: B6.Cg-Tg (FucciS/G2/M) #504Bsi Tg (FucciG1) #596Bsi

For more details

|  Announcement: Japanese Conference for Laboratory Animal Science and
|  Technology,Sapporo 2014

  Japanese Conference for Laboratory Animal Science and Technology,
Sapporo 2014 will be held at Sapporo Convention Center from May 15
through to 17. Dr. Yoshiki, Head of Experimental Animal Division RIKEN
BRC will talk on "Genetic Monitoring at RIKEN BRC" and also Dr. Nakata,
Senior Technical Scientist will present "Genetic quality test for
multiple transgenes of genetically-modified mice" at symposium Ⅵ on May

Japanese Conference for Laboratory Animal Science and Technology,
Sapporo 2014

|  User publications

  The following results have been newly reported by users. We are
honored to introduce new publications to the science community.
Therefore, we look forward to receiving your publications too.

RBRC01361  C57BL-p53+/-
Okita N, Ishikawa N, Mizunoe Y, Oku M, Nagai W, Suzuki Y, Matsushima S,
Mikami K, Okado H, Sasaki T, Higami Y. Inhibitory effect of p53 on
mitochondrial content and function during adipogenesis. Biochem Biophys
Res Commun., pii: S0006-291X(14)00321-0, doi: 10.1016/j.bbrc.2014.02.
059, 2014.

RBRC02290  STOCK Tg(Nanog-GFP,Puro)1Yam
Koga M, Matsuda M, Kawamura T, Sogo T, Shigeno A, Nishida E, Ebisuya M.
Foxd1 is a mediator and indicator of the cell reprogramming process.
Nat Commun.;5:3197, doi: 10.1038/ncomms4197, 2014.

RBRC02302  B6.129P2-Lyzs<tm1(cre)Ifo>
Akbari M, Honma K, Kimura D, Miyakoda M, Kimura K, Matsuyama T, Yui K.
IRF4 in dendritic cells Inhibits IL-12 production and controls Th1
immune responses against Leishmania major. J. Immunol.;192(5):2271-9,
doi: 10.4049/jimmunol.1301914, 2014.

|  Newly deposited mouse strains

The following mice have been newly deposited with RIKEN BRC and will be
available shortly after rederivation.
We appreciate the contributions of the depositors to the science

Dr. Kyoko Miyasaka, Tokyo Kasei University
  RBRC06197  B6.129S4-Cckar<tm1Kym>

Dr. Toshiyuki Fukada, RIKEN Center for Integrative Medical Sciences (IMS)
  RBRC06217  B6;129-Slc39a13<tm1Thir>

Dr. Takahisa Furukawa, Institute for Protein Research, Osaka University
  RBRC06218  C57BL/6-Susd3<tm1(KOMP)Vlcg>
  RBRC06219  C57BL/6-Frmpd1<tm1Tfur>
  RBRC06220  B6.Cg-Tg(Syn1-creERT2)1Tfur

Dr. Minoru Tanaka, Nippon Veterinary and Life Science University
  RBRC06232  B6.129S2-Prl<tm1Hmn>

Dr. Hiroyuki Sorimachi, Tokyo Metropolitan Institute of Medical Science
  RBRC06237  B6.Cg-Capn6<tm1Hiso>
  RBRC06238  ICR.Cg-Capn6<tm1Hiso>

Dr. Masato Tanaka, Tokyo University of Pharmacy and Life Sciences
  RBRC06239  C57BL/6-Siglec1<tm1(cre)Mtaka>

Dr. Tadatsugu Taniguchi, The University of Tokyo, Graduate School of
  RBRC06240  B6.129P2-Hmgb1<tm1Ttg>

Dr. Keigo Nishida, RIKEN Center for Integrative Medical Sciences (IMS)
  RBRC06244  B6.Cg-Gab2<tm2.1Thir>
  RBRC06245  B6.Cg-Gab2<tm3.1Thir>
  RBRC06246  B6.Cg-Gab2<tm4.1Thir>
  RBRC06247  B6.Cg-Gab2<tm5.1Thir>

Dr. Atsushi Iwama, Graduate School of Medical and Pharmaceutical
Sciences, Chiba University
  RBRC06248  B6.129-Brd1<tm2Hko>

|  Newly available mouse strains

The following mice have recently been rederived into our barrier
facility and are now available for distribution.

  RBRC05523  B6.129S7-Sox9<tm1(cre)Crm>
  RBRC05600  B6.129(Cg)-Rab7<tm1Ywd>
  RBRC05911  B6.129S6-Cd109<tm1Mat>
  RBRC05921  B6;129P2-Eed<tm1(L240Q)Homy>
  RBRC06086  C57BL/6-Tg(Arc-EGFP/Arc)3Hbto
  RBRC06135  B6.Cg-Fad24<tm1Maim>/35F

|  Mouse strains for freeze preservation

Since a sufficient number of frozen stocks have been preserved, live
mice of the following strains will be discontinued soon.
It will take more than 3 months to recover live mice from frozen stock.
Therefore, please inform us as soon as possible if you plan to use the
mice and request them alive.

  RBRC03328  TL5 KO
  RBRC05515  B6;129S4-Ern1<tm2.1Tiw>
  RBRC05761  B6.Cg-Rftn1<tm1Ayos>
  RBRC05822  C57BL/6J-Tg(hSMA-NCX1*trun)1
  RBRC05828  C57BL/6J-Tg(hSMA-MgT1)1
  RBRC05887  B6;129P2-Bri3bp<Gt(RST655)Byg>/Dkit
  RBRC05894  B6.ICR-Fgf5<go-moja>/Utr
  RBRC05920  C57BL/6J-Tg(Cdh5-rtTA)1

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RIKEN BioResource Center
Experimental Animal Division
3-1-1 Koyadai, Tsukuba-shi
Ibaraki, 305-0074 Japan