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Cryopreservation of Mouse Embryos by Ethylene Glycol-Based Vitrification
JoVE 3155 11/18/2011

RIKEN BioResource Center Mouse E-mail News No. 111

RIKEN BioResource Center (BRC) is pleased to update you with the latest

======= Contents ======================================================
- Special topic: Mouse of the Month 
  "Cell signaling of stress response via ASK1"
- Training course for cryopreservation of mouse sperm and embryos
- Report: The 3rd RIKEN BRC/ Nanjing University MARC International 
  Summer Intensive Course of the Mouse
- Announcement: The 73rd Annual Meeting of the Japanese Cancer 
- Depositor publications
- User publications
- Newly deposited mouse strains
- Newly available mouse strains

|  Special topic: Mouse of the Month    August 2014

Cell signaling of stress response via ASK1
RBRC05753  B6.129S4-Map3k5<tm1Hijo>/HijoRbrc

Depositor: Hidenori Ichijo, D.D.S., Ph.D.
Graduate School of Pharmaceutical Sciences, The University of Tokyo

Mouse of the Month archive

|  Training course for cryopreservation of mouse sperm and embryos

 We will provide hands-on training of basic laboratory techniques to
produce and maintain specific mouse strains, including in vitro 
fertilization as well as cryopreservation of mouse sperm and embryos. 
We will also demonstrate micro-insemination operation and nuclear-
transplantation cloning.

Dates: From October 6 to 9, 2014  4 consecutive days
Place: BioResourse Center main building, RIKEN Tsukuba Institute
Tuition: 17,000yen
Capacity of enrollment: 3-4 people
Application deadline: September 9, 2014

|  Report: The 3rd RIKEN BRC/ Nanjing University MARC International 
|  Summer Intensive Course of the Mouse

Model Animal Research Center (MARC), Nanjing University, China and 
RIKEN BRC have been co-organizing a short educational course focusing 
on mouse genetics and related experimental technologies for young 
scientists. This year, RIKEN BRC hosted the 3rd course from July 28 to 
30 in Tsukuba and had 18 participants from 5 countries. We sincerely 
express our thanks to all participants. 
The next 4th Summer Course is planned to take place at MARC in Nanjing 
from July 27 to 29, 2015.

|  Announcement: The 73rd Annual Meeting of the Japanese Cancer 
|  Association

The 73rd Annual Meeting of the Japanese Cancer Association will be held
at PACIFICO Yokohama from Thursday, September 25th to Saturday, 
September 27th. We are pleased to welcome you to visit our booth in the
exhibition hall during the annual meeting.

The 73rd Annual Meeting of the Japanese Cancer Association

|  Depositor publications

Two papers of RBRC06221 B6;129-Slc39a10<tm1>(ZIP10 KO)have been 
published online in PNAS Early Edition. This strain has been deposited 
by Dr. Toshiyuki Fukada, Visiting Scientist, Laboratory for 
Homeostatic Network, RIKEN IMS and Assistant Professor, Division of 
Pathology, Department of Oral Diagnostic Sciences, School of Dentistry,
Showa University.

Miyai T, Hojyo S, Ikawa T, Kawamura M, Irié T, Ogura H, Hijikata A, 
Bin BH, Yasuda T, Kitamura H, Nakayama M, Ohara O, Yoshida H, Koseki H,
Mishima K, Fukada T. "Zinc transporter SLC39A10/ZIP10 facilitates 
antiapoptotic signaling during early B-cell development" PNAS, 2014, 
doi: 10.1073/pnas.1323549111.

Hojyo S, Miyai T, Fujishiro H, Kawamura M, Yasuda T, Hijikata A, Bin BH,
Irié T, Tanaka J, Atsumi T, Murakami M, Nakayama M, Ohara O, Himeno S, 
Yoshida H, Koseki H, Ikawa T, Mishima K, Fukada T. "Zinc transporter 
SLC39A10/ZIP10 controls humoral immunity by modulating B cell receptor 
signal strength" PNAS, 2014, doi: 10.1073/pnas.1323557111

|  User publications

The following results have been newly reported by users. We are honored
to introduce new publications to the science community. Therefore, we 
look forward to receiving your publications too.

RBRC00806  B6.Cg-Tg(CAG-GFP/LC3)53Nmz/NmzRbrc  «GFP-LC3#53»
Maday S, Holzbaur EL. Autophagosome biogenesis in primary neurons 
follows an ordered and spatially regulated pathway. Dev Cell.; 30(1):
71-85, doi: 10.1016/j.devcel.2014.06.001, 2014.

RBRC01828  B6.Cg-Tg(CAG-Cre)CZ-M02Osb/OsbRbrc
Inoue SI, Moriya M, Watanabe Y, Miyagawa-Tomita S, Niihori T, Oba D, 
Ono M, Kure S, Ogura T, Matsubara Y, Aoki Y. New BRAF knockin mice 
provide a pathogenetic mechanism of developmental defects and a 
therapeutic approach in cardio-facio-cutaneous syndrome. Hum Mol Genet.
pii: ddu376, 2014.

RBRC01828  B6.Cg-Tg(CAG-Cre)CZ-M02Osb/OsbRbrc
Liu T, Yamaguchi Y, Shirasaki Y, Shikada K, Yamagishi M, Hoshino K, 
Kaisho T, Takemoto K, Suzuki T, Kuranaga E, Ohara O, Miura M. Single-
Cell Imaging of Caspase-1 Dynamics Reveals an All-or-None Inflammasome 
Signaling Response. doi: 10.1016/j.celrep.2014.07.012, 2014.

RBRC01888  B6(C)-Kit<W-sh>/Rbrc  «C57BL/6-Wsh/Wsh»
Iwanaga K, Nakamura T, Maeda S, Aritake K, Hori M, Urade Y, Ozaki H, 
Murata T.
Mast cell-derived prostaglandin D2 inhibits colitis and colitis-
associated colon cancer in mice. Cancer Res.; 74(11):3011-9, doi: 
10.1158/0008-5472.CAN-13-2792, 2014.

|  Newly deposited mouse strains

 The following mice have been newly deposited with RIKEN BRC and will 
be available shortly after rederivation.
We appreciate the contributions of the depositors to the science 

Dr. Masashi Yanagisawa, University of Texas Southwestern Medical Center
at Dallas
RBRC06322    B6.Cg-Edn1<tm1Ywa>
RBRC06323    B6.Cg-Ednra<tm2Ywa>
RBRC06324    B6.Cg-Tg(DBH-Ednrb)Ywa

Dr. Brian Seed, Massachusetts General Hospital
RBRC06331    B6;129-Dtx4<Gt(431E3)Cmhd>

Dr. Takaomi C. Saido, RIKEN
RBRC06343    C57BL/6-App<tm2(NL-F)Tcs>
RBRC06344    C57BL/6-App<tm3(NL-G-F)Tcs>

Dr. Eisuke Mekada, Osaka University
RBRC06381    C57BL/6N-Tspan11<tm1a(EUCOMM)Osb>/10F
RBRC06382    C57BL/6N-Tspan11<tm1a(EUCOMM)Osb>/12H
RBRC06383    C57BL/6N-Tspan11<tm1b(EUCOMM)Osb>/10F
RBRC06384    C57BL/6N-Tspan11<tm1b(EUCOMM)Osb>/12H

Dr. Takashi Maruyama, Graduate School of Medicine, Gifu University
RBRC06410    B6.Cg-Nfkbiz<tm1.1Muta>

Dr. Takao Hamakubo, Research Center for Advanced Science and Technology,
The University of Tokyo
RBRC06412    B6;129-Wtap<Gt(OST200529)Lex>

Dr. Masayuki Miura, The University of Tokyo
RBRC06427    B6.Cg-Gt(ROSA)26Sor<tm1(CAG-SCAT1)Miur>
RBRC06434    B6.Cg-Gt(ROSA)26Sor<tm1.1(CAG-SCAT1)Miur>

|  Newly available mouse strains

The following mice have recently been rederived into our barrier 
facility and are now available for distribution.

RBRC02794    Vps52 #95(Acc.No.CDB0767K)
RBRC06040    ICR.Cg-Hcn4<tm1(tTA)>/1Kyo
RBRC06220    B6.Cg-Tg(Syn1-creERT2)1Tfur
RBRC06240    B6.129P2-Hmgb1<tm1Ttg>
RBRC06258    C57BL/6-Tg(Cacng5-EGFP)500Bsi
RBRC06308    B6.129-(D1Mit501-Fcgr2b) Fcgr2b<tm1Ttk>/Hros
RBRC06312    ICR.Cg-Mesp2<tm7.1(mespb)Ysa>
RBRC06328    B6(C)-Tg(Col2a1-Ctgf,lacZ)05908-01-2Hatt

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RIKEN BioResource Center
Experimental Animal Division
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Ibaraki, 305-0074 Japan