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Video protocol

Cryopreservation of Mouse Embryos by Ethylene Glycol-Based Vitrification
JoVE 3155 11/18/2011

RIKEN BioResource Center Mouse E-mail News No. 114


RIKEN BioResource Center (BRC) is pleased to update you with the latest
information.

======= Contents ===============================================
- Special topic: Mouse of the Month 
 "C429S mutation in the mouse β-catenin gene leads to infertility"
- A new angle on infertility
- BRC Current Technology "Nuclear transfer from germ cells"
- Announcement: The 43rd Annual Meeting of The Japanese Society for
 Immunology
- Holiday closing announcement
- User publications
- Our publications
==============================================================

+-----------------------------------------------------------------------
|  Special topic: Mouse of the Month    November 2014
+-----------------------------------------------------------------------

C429S mutation in the mouse β-catenin gene leads to infertility
  RBRC06153  B6.Cg-Tg(TOPGAL) Ctnnb1<Rgsc1880>/Rbrc
  RBRC06154  B6(D2)-Ctnnb1<Rgsc1880>/Rbrc

Depositor: Yoichi Gondo, Ph.D.
Mutagenesis and Genomics Team, RIKEN BioResource Center

  https://www.brc.riken.jp/lab/animal/mailnews/nm201411_01.html

Mouse of the Month archive
  https://www.brc.riken.jp/lab/animal/en/mouse_of_month_list.shtml

+-----------------------------------------------------------------------
|  A new angle on infertility
+-----------------------------------------------------------------------

  Drs. Yoichi Gondo, Takuya Murata and their Mutagenesis and Genomics
Team of RIKEN BRC have discovered that a single mutation in the 
β-catenin gene, which codes a protein known to be deeply involved
in a number of developmental and homeostatic processes, can lead to
infertility not through a disruption of the production of egg or sperm
cells, but rather by leading to abnormalities in the morphology of the
sexual organs, making natural reproduction impossible. It was published
in Scientific Reports online edition on November 7th. 

Takuya Murata, Yuichi Ishitsuka, Kumiko Karouji, Hideki Kaneda,
Hideaki Toki, Yuji Nakai, Shigeru Makino, Ryutaro Fukumura,
Hayato Kotaki, Shigeharu Wakana, Tetsuo Noda, and Yoichi Gondo,
"β-catenin<C429S> mice exhibit sterility consequent to spatiotemporally
sustained Wnt signalling in the internal genitalia", Scientific Reports,
2014, doi: 10.1038/srep06959
http://dx.doi.org/10.1038/srep06959

The following strains used in the above paper are available at RIKEN BRC.
  RBRC06153  B6.Cg-Tg(TOPGAL) Ctnnb1<Rgsc1880>/Rbrc
  RBRC06154  B6(D2)-Ctnnb1<Rgsc1880>/Rbrc
  RBRC-GD000125  Ctnnb1<Rgsc01880>

http://www.riken.jp/en/pr/press/2014/20141107_2/

+-----------------------------------------------------------------------
|  BRC Current Technology  "Nuclear transfer from germ cells"
+-----------------------------------------------------------------------

For the study of developmental epigenetics
  https://www.brc.riken.jp/lab/animal/current_tech/current_tech_1411e.html

BRC Current Technology archive
  https://www.brc.riken.jp/lab/animal/en/current_tech_list.shtml

+-----------------------------------------------------------------------
|  Announcement: The 43rd Annual Meeting of The Japanese Society for
|  Immunology
+-----------------------------------------------------------------------

  The 43rd Annual Meeting of The Japanese Society for Immunology will be
held at Kyoto International Conference Center from Wednesday, December
10th to Friday, December 12th. It is our pleasure to invite you to visit
our booth in the event hall.

The 43rd Annual Meeting of The Japanese Society for Immunology
  http://www.jsi-men-eki.org/jsi43/index.html

+-----------------------------------------------------------------------
|  Holiday closing announcement
+-----------------------------------------------------------------------

  We will be closing from December. 27, 2014 through January 4, 2015 due
to New Year's holidays. We will resume normal business from January 5,
2015.
  We wish you a wonderful holiday season, and all the best for the New
Year!

+-----------------------------------------------------------------------
|  User publications
+-----------------------------------------------------------------------

  The following results have been newly reported by users. We are
honored to introduce new publications to the science community.
Therefore, we look forward to receiving your publications too.

RBRC00639  JF1/MsRbrc  «JF1/Msf»
Kamimura S, Hatanaka Y, Hirasawa R, Matsumoto K, Oikawa M, Lee J,
Matoba S, Mizutani E, Ogonuki N, Inoue K, Kohda T, Ishino F, Ogura A.
Establishment of Paternal Genomic Imprinting in Mouse Prospermatogonia
Analyzed by Nuclear Transfer. Biol Reprod.;91:120, 2014.
http://www.ncbi.nlm.nih.gov/pubmed/25232016

RBRC00806  B6.Cg-Tg(CAG-GFP/LC3)53Nmz/NmzRbrc  «GFP-LC3#53»
Katamura M, Iwai-Kanai E, Nakaoka M, Okawa Y. Curcumin Attenuates
Doxorubicin-Induced Cardiotoxicity by Inducing Autophagy via the
Regulation of JNK Phosphorylation. J. Clin. Exp. Cardiolog;5:337, 2014.
http://dx.doi.org/10.4172/2155-9880.1000337

RBRC01071  B6.129P2-Rbpj<tm1Hon>/HonRbrc  «Floxed RBP-J»
Obata Y, Kimura S, Nakato G, Iizuka K, Miyagawa Y, Nakamura Y,
Furusawa Y, Sugiyama M, Suzuki K, Ebisawa M, Fujimura Y, Yoshida H,
Iwanaga T, Hase K, Ohno H. Epithelial-stromal interaction via Notch
signaling is essential for the full maturation of gut-associated
lymphoid tissues. EMBO Rep., doi:10.15252/embr.201438942, 2014.
http://dx.doi.org/10.15252/embr.201438942

RBRC01294  B6.Cg-Tg(CAT-Rho-K DN)3-1Koba/KobaRbrc  «CAT-Rho-K DN/3-1»
Noda K, Nakajima S, Godo S, Saito H, Ikeda S, Shimizu T, Enkhjargal B,
Fukumoto Y, Tsukita S, Yamada T, Katagiri H, Shimokawa H. Rho-Kinase
Inhibition Ameliorates Metabolic Disorders through Activation of AMPK
Pathway in Mice. PLoS One;9:e110446, 2014.
http://www.ncbi.nlm.nih.gov/pubmed/25365359

RBRC01834  C57BL/6-Tg(CAG-FLPe)36Ito/ItoRbrc  «B6-Tg(CAG-FLPe)36»
Kawakami E, Tokunaga A, Ozawa M, Sakamoto R, Yoshida N. The histone
demethylase fbxl11/kdm2a plays an essential role in embryonic
development by repressing cell-cycle regulators. Mechanisms of
Development, doi:10.1016/j.mod.2014.10.001, 2014.
http://dx.doi.org/10.1016/j.mod.2014.10.001

+-----------------------------------------------------------------------
|  Our publications
+-----------------------------------------------------------------------

Mekada K, Hirose M, Murakami A, Yoshiki A. Development of SNP Markers
for C57BL/6N-Derived Mouse Inbred Strains. Exp Anim.; 64:91-100, doi:
10.1538/expanim.14-0061, 2014.
http://dx.doi.org/10.1538/expanim.14-0061

__________________________________________________________________
*We hope you find the contents of this message of interest.
 However, if you would prefer to unsubscribe from future e-mails, please
 send an e-mail to animal@brc.riken.jp.

*If you have any questions or comments, please send an e-mail to
 animal@brc.riken.jp.

*Content is subject to change without notice.

*All Rights Reserved.
__________________________________________________________________
RIKEN BioResource Center
Experimental Animal Division
3-1-1 Koyadai, Tsukuba-shi
Ibaraki, 305-0074 Japan
animal@brc.riken.jp
https://www.brc.riken.jp/lab/animal/en/
__________________________________________________________________
2014.12.05