Frequently used strains and publications


Quality Control

Technical information

Customer service


  Order Form


Video protocol

Cryopreservation of Mouse Embryos by Ethylene Glycol-Based Vitrification
JoVE 3155 11/18/2011

RIKEN BioResource Center Mouse E-mail News No. 116

RIKEN BioResource Center Mouse E-mail News   No. 116

RIKEN BioResource Center (BRC) is pleased to update you with the latest

======= Contents ===============================================
- Special topic: Mouse of the Month
  "Clarifying the role of Fbxw7 in cancer"
- User publications
- Newly deposited mouse strains
- Newly available mouse strains
- Mouse strains for freeze preservation

|  Special topic: Mouse of the Month    January 2015

Clarifying the role of Fbxw7 in cancer
  RBRC06393, floxed mouse  B6;129P2-Fbxw7<tm1Kei>
  RBRC06394, knockout mouse  B6;129P2-Fbxw7<tm1Kin>

Depositor: Keiichi Nakayama, M.D., Ph.D.
Department of Molecular and Cellular Biology
Medical Institute of Bioregulation, Kyushu University

Mouse of the Month archive

|  User publications

  The following results have been newly reported by users. We are
honored to introduce new publications to the science community.
Therefore, we look forward to receiving your publications too.

RBRC00267  C57BL/6-Tg(CAG-EGFP)C14-Y01-FM131Osb/OsbRbrc
Shinagawa T, Takagi T, Tsukamoto D, Tomaru C, Huynh LM, Sivaraman P,
Kumarevel T, Inoue K, Nakato R, Katou Y, Sado T, Takahashi S, Ogura A,
Shirahige K, Ishii S. Histone variants enriched in oocytes enhance
reprogramming to induced pluripotent stem cells. Cell Stem Cell. ;14:

RBRC00398  B6.129P2-Mmp2<tm1Ito>/ItoRbrc  «GelA KO»
Cinq-Fraisa C, Coatrieux C, Savary A, D'Angelo R, Bernis C, Salvayre R,
Nègre-Salvayrea A, Augéa N. Annexin II-dependent actin remodeling
evoked by hydrogen peroxide requires the metalloproteinase/sphingolipid
pathway. Redox Biology; 4C:169-179.

RBRC00494  B10.MOL-TEN1/Ms
Hirawatari K, Hanzawa N, Kuwahara M, Aoyama H, Miura I, Wakana S,
Gotoh H. Polygenic Expression of Teratozoospermia and Normal Fertility
in B10.MOL-TEN1 Mouse Strain. Congenit Anom (Kyoto), doi:

RBRC00806  B6.Cg-Tg(CAG-GFP/LC3)53Nmz/NmzRbrc  «GFP-LC3#53»
Zheng DM, Bian Z, Furuya N, Oliva Trejo JA, Takeda-Ezaki M, Takahashi K,
Hiraoka Y, Mineki R, Taka H, Ikeda SI, Komatsu M, Fujimura T, Ueno T,
Ezaki J. A treadmill exercise reactivates the signaling of the mammalian
target of rapamycin (mTor) in the skeletal muscles of starved mice.
Biochem Biophys Res Commun. ;456:519-26.

RBRC00806  B6.Cg-Tg(CAG-GFP/LC3)53Nmz/NmzRbrc  «GFP-LC3#53»
Kashiwagi A, Hosokawa S, Maeyama Y, Ueki R, Kaneki M, Martyn JA,
Yasuhara S. Anesthesia with Disuse Leads to Autophagy Up-regulation in
the Skeletal Muscle. Anesthesiology.

RBRC00897  B6.Cg-Aicda<tm1Hon>/HonRbrc
Kato M, Tsuji-Kawahara S, Kawasaki Y, Kinoshita S, Chikaishi T,
Takamura S, Fujisawa M, Kawada A, Miyazawa M. Class Switch Recombination
and Somatic Hypermutation of Virus-Neutralizing Antibodies Are Not
Essential for Control of Friend Retrovirus Infection. J. Virol. ;89:

RBRC01059  NC/NgaRbrc
Knitlova J, Hajkova V, Voska L, Elsterova J, Obrova B, Melkova Z.
Development of Eczema Vaccinatum in Atopic Mouse Models and Efficacy of
MVA Vaccination against Lethal Poxviral Infection. PLoS One. ;9:e114374.

RBRC01345  B6.129P2-Emx1<tm1.1(cre)Ito>/ItoRbrc  «Emx1-Cre KI Δneo»
Sato T, Ishikawa M, Mochizuki M, Ohta M, Ohkura M, Nakai J, Takamatsu N,
Yoshioka K. JSAP1/JIP3 and JLP regulate kinesin-1-dependent axonal
transport to prevent neuronal degeneration. Cell Death Differ. doi:

RBRC01420  B6;129P2-Irf7<tm1Ttg>/TtgRbrc  «IRF-7-KO, IRF7»
Temizoz B, Kuroda E, Ohata K, Jonai N, Ozasa K, Kobiyama K, Aoshi T,
Ishii KJ. TLR9 and STING agonists synergistically induce innate and
adaptive type II IFN. Eur J Immunol. doi: 10.1002/eji.201445132.

RBRC02228  ICR.Cg-Tg(TOPGAL)/YsaRbrc  «TOP-GAL»
Murata T, Ishitsuka Y, Karouji K, Kaneda H, Toki H, Nakai Y, Makino S,
Fukumura R, Kotaki H, Wakana S, Noda T, Gondo Y. β-CateninC429S mice
exhibit sterility consequent to spatiotemporally sustained Wnt
signalling in the internal genitalia. Sci Rep. ;4:6959.

RBRC02298  C.129S2(B6)-Il3<tm1Glli>/Rbrc  «C.Cg-Il3<tm1Glli>»
Motomura Y, Morita H, Moro K, Nakae S, Artis D, Endo TA, Kuroki Y,
Ohara O, Koyasu S, Kubo M. Basophil-derived interleukin-4 controls the
function of natural helper cells, a member of ILC2s, in lung
inflammation. Immunity.;40:758-71.

RBRC02370  B6.129-Grn<tm1Mni>
Hosokawa M, Arai T, Masuda-Suzukake M, Kondo H, Matsuwaki T,
Nishihara M, Hasegawa M, Akiyama H. Progranulin Reduction Is Associated
With Increased Tau Phosphorylation in P301L Tau Transgenic Mice.
J Neuropathol Exp Neurol.;74:158-65.

RBRC02759  B6.Cg-Atg7<tm1Tchi>/TchiRbrc
Walter KM, Schonenberger MJ, Trotzmuller M, Horn M, Elsasser HP,
Moser AB, Lucas MS, Schwarz T, Gerber PA, Faust PL, Moch H, Kofeler HC,
Krek W, Kovacs WJ. Hif-2α promotes degradation of Mammalian peroxisomes
by selective autophagy. Cell Metab.;20:882-97.

RBRC02759  B6.Cg-Atg7<tm1Tchi>/TchiRbrc
Song ZH, Yu HY, Wang P, Mao GK, Liu WX, Li MN, Wang HN, Shang YL, Liu C,
Xu ZL, Sun QY, Li W. Germ cell-specific Atg7 knockout results in primary
ovarian insufficiency in female mice. Cell Death Dis. ;6:e1589.

|  Newly deposited mouse strains

  The following mice have been newly deposited with RIKEN BRC and will
be available shortly after rederivation.
  We appreciate the contributions of the depositors to the science

Dr. Tasuku Honjo, Graduate School of Medicine, Kyoto University
  RBRC06296    CAJcl.Cg-Aicda<tm2.1Hon>
  RBRC06297    CAJcl.Cg-Aicda<tm1Hon>
  RBRC06298    CAnPt.Cg-Aicda<tm2.1Hon>
  RBRC06299    CAnPt.Cg-Aicda<tm1Hon>
  RBRC06300    CAnPt.Cg-Aicda<tm1Hon>/+

Dr. Syogo Endou, Tokyo Metropolitan Institute of Gerontology
  RBRC06468    C57BL/6J-Ppp1r17<tm1Nkz>

Dr. Kazuo Kinoshita, Research Institute, Shiga Medical Center
  RBRC06514    STOCK Dock5<Gt(AN0268)Wtsi>/Shigm

Dr. Kyoji Ikeda, National Center for Geriatrics and Gerontology
  RBRC06522    B6.Cg-Cthrc1<tm1.1Suna>
  RBRC06523    B6.Cg-Cthrc1<tm1.2Suna>
  RBRC06524    C57BL/6-Tg(CAG-Cthrc1)1Suna
  RBRC06525    C57BL/6-Tg(CAG-Cthrc1)100Suna

Dr. Kou-ichi Jishage, Chugai Pharmaceutical Co.,Ltd.
  RBRC06533    C57BL/6N-Tifab<tm1Csk>
  RBRC06534    B6;129S6-Fcrl6<tm1Csk>

Dr. Tamio Ohno, Nagoya University
  RBRC06535    C3.NSY-(D11Nds3-D11Mit261)

Dr. Haruhiko Koseki, RIKEN Center for Integrative Medical Sciences (IMS)
  RBRC06537    B6.Cg-Cdkal1<tm1.1Hko>
  RBRC06538    B6.Cg-Lhx3<tm1.1Hko>

|  Newly available mouse strains

  The following mice have recently been rederived into our barrier
facility and are now available for distribution.

  RBRC03556    B6.129-Dmd<tm1Mok>
  RBRC03559    129.Cg-Pax7<tm2Pgr>
  RBRC06134    C57BL/6-Tg(Oog1*3.9-AcGFP)B
  RBRC06249    B6.129-Ret<tm1Mat>
  RBRC06331    B6;129-Dtx4<Gt(431E3)Cmhd>
  RBRC06336    NOD.Cg-Prkdc<scid> E2f1<tm1Meg>
  RBRC06339    ICR.Cg-Tg(Olfr1507-cre)1Hsak
  RBRC06352    B6.129S4-Asf1a<Gt(S7-4B1)Sor>/Skmz
  RBRC06386    B6.Cg-Tg(Nepro-venus)1Tets
  RBRC06393    B6;129P2-Fbxw7<tm1Kei>
  RBRC06410    B6.Cg-Nfkbiz<tm1.1Muta>
  RBRC06412    B6;129-Wtap<Gt(OST200529)Lex>

|  Mouse strains for freeze preservation

  Since a sufficient number of frozen stocks have been preserved, live
mice of the following strains will be discontinued soon.
It will take more than 3 months to recover live mice from frozen stock.
Therefore, please inform us as soon as possible if you plan to use the
mice and request them alive.

  RBRC02132    B6.Cg-Tg(Hils-EGFP)2Htan
  RBRC05945    ICR.Cg-Pax6<tm1Ued>

*We hope you find the contents of this message of interest.
 However, if you would prefer to unsubscribe from future e-mails, please
 send an e-mail to

*If you have any questions or comments, please send an e-mail to

*Content is subject to change without notice.

*All Rights Reserved.
RIKEN BioResource Center
Experimental Animal Division
3-1-1 Koyadai, Tsukuba-shi
Ibaraki, 305-0074 Japan