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RIKEN BioResource Center Mouse E-mail News No. 132

RIKEN BioResource Center Mouse E-mail News No. 132

RIKEN BioResource Center (BRC) is pleased to update you with the latest

======= Contents ===============================================
- Special topic: Mouse of the Month
  "Whole-body in vivo monitoring using human IL6-luciferase transgenic mice"
- The Fifth RIKEN BRC-Nanjing University MARC Mouse Resource Workshop 2016
- User publications
- Newly deposited mouse strains

| Special topic: Mouse of the Month May 2016

Whole-body in vivo monitoring using human IL6-luciferase transgenic mice
  RBRC09487 B6.Cg-Tg(IL6-luc)Mym Tyr<c-Brd>

Depositor: Masayuki Yamamoto, M.D., Ph.D.
           Department of Medical Biochemistry
           Tohoku University Graduate School of Medicine

Mouse of the Month archive

| The Fifth RIKEN BRC-Nanjing University MARC Mouse Resource Workshop 2016

The 5th RIKEN BRC-Nanjing University MARC Mouse Resource Workshop 2016 
will be held at RIKEN BioResource Center from July 25 to 27. The workshop
will focus on Biological Imaging of Disease Models, which has become increasingly 
important for biomedical science.

  Place: RIKEN BioResource Center
  Date: July 25-27, 2016
  Official Language: English
  Registration Fee: Free
  Application Deadline: July 15

| User publications

The following result has been newly reported by users. We are
honored to introduce new publications to the science community.
Therefore, we look forward to receiving your publications too.

RBRC00144 C57BL/6-Ly5.1
Tanaka Y, Nagashima H, Bando K, Lu L, Ozaki A, Morita Y, 
Fukumoto S, Ishii N, Sugawara S. Oral CD103-CD11b+ classical 
dendritic cells present sublingual antigen and induce Foxp3+ 
regulatory T cells in draining lymph nodes. Mucosal Immunol. 
doi: 10.1038/mi.2016.46, 2016.

RBRC01071 Floxed RBP-J
M Taketo, M Sonoshita, Y Sakai, K Kawada, Y Itatani. 
WO 2014185550.

RBRC01099 ERAI mice [ER stress-activated indicator (ERAI)]
Bhootada Y, Kotla P, Zolotukhin S, Gorbatyuk O, Bebok Z, 
Athar M, Gorbatyuk M. Limited ATF4 Expression in Degenerating 
Retinas with Ongoing ER Stress Promotes Photoreceptor Survival 
in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa. 
PLoS One.;11(5):e0154779, 2016.

RBRC01294 CAT-Rho-K DN/3-1
Otsu K, Ida-Yonemochi H, Fujiwara N, Harada H. The Semaphorin 
4D-RhoA-Akt Signal Cascade Regulates Enamel Matrix Secretion 
in Coordination with Cell Polarization During Ameloblast 
Differentiation. J. Bone Miner Res., doi: 10.1002/jbmr.2876., 2016.

RBRC01348 ICR.Cg-Trp53<tm1Sia>/Rbrc [ICR-p53+/-]
Maruzuru Y, Koyanagi N, Takemura N, Uematsu S, Matsubara D, 
Suzuki Y, Arii J, Kato A, Kawaguchi Y. p53 is a Host Cell 
Regulator during Herpes Simplex Encephalitis. J. Virol. 
pii: JVI.00846-16, 2016.

RBRC01390 B6.129P2-Nfe2l2<tm1Mym>/MymRbrc [Nrf2 KO mouse/C57BL6J]
Suzuki R, Nakamura Y, Chiba S, Mizuno T, Abe K, Horii Y, 
Nagashima H, Tanita T, Yamauchi K. Mitigation of tight 
junction protein dysfunction in lung microvascular 
endothelial cells with pitavastatin. Pulm Pharmacol Ther., 
doi: 10.1016/j.pupt.2016.04.003, 2016.

RBRC01420 B6;129P2-Irf7<tm1Ttg>/TtgRbrc [IRF-7-KO, IRF7, C57BL/6J]
Puthia M, Ambite I, Cafaro C, Butler D, Huang Y, Lutay N, 
Rydström G, Gullstrand B, Swaminathan B, Nadeem A, Nilsson B, 
Svanborg C. IRF7 inhibition prevents destructive innate 
immunity-A target for nonantibiotic therapy of bacterial 
infections. Sci Transl Med.;8(336):336ra59, 2016.

RBRC01828 B6.Cg-Tg(CAG-Cre)CZ-MO2Osb [CAG-cre]
Naganuma T, Takagi S, Kanetake T, Kitamura T, Hattori S, 
Miyakawa T, Sassa T, Kihara A. Disruption of the Sjögren-Larsson 
Syndrome Gene Aldh3a2 in Mice Increases Keratinocyte Growth and 
Retards Skin Barrier Recovery. J. Biol. Chem.;291(22):11676-88, 2016.

RBRC01834 C57BL/6-Tg(CAG-flpe)36Ito/ItoRbrc [B6-Tg(CAG-FLPe)36]
Sugimoto M, Shimizu Y, Zhao S, Ukon N, Nishijima K, Wakabayashi M, 
Yoshioka T, Higashino K, Numata Y, Okuda T, Tamaki N, Hanamatsu H, 
Igarashi Y, Kuge Y. Characterization of the role of sphingomyelin 
synthase 2 in glucose metabolism in whole-body and peripheral 
tissues in mice. Biochim Biophys Acta. ;1861(8 Pt A):688-702, 2016.

RBRC01834 C57BL/6-Tg(CAG-flpe)36Ito/ItoRbrc [B6-Tg(CAG-FLPe)36]
Nagamachi A, Nakata Y, Ueda T, Yamasaki N, Ebihara Y, Tsuji K, 
Honda Z, Takubo K, Suda T, Oda H, Inaba T, Honda H. 
Acquired deficiency of A20 results in rapid apoptosis, systemic 
inflammation, and abnormal hematopoietic stem cell function. 
PLoS One.;9(1):e87425, 2014.

RBRC02370 B6;129-Grn<tm1> [Progranulin KO mouse]
Anja Stundl, Die Rolle des Wachstumsfaktors Progranulin in 
der Progression der Atherosklerose: eine in vivo - Studie 
im Mausmodell. Dissertation, LMU München: Medizinische Fakultät, 2016

RBRC03706 DS/Shi
Okamoto K, Koda M, Okamoto T, Onoyama T, Miyoshi K, Kishina M, 
Kato J, Tokunaga S, Sugihara TA, Hara Y, Hino K, Murawaki Y. 
A Series of microRNA in the Chromosome 14q32.2 Maternally 
Imprinted Region Related to Progression of Non-Alcoholic 
Fatty Liver Disease in a Mouse Model. PLoS One.;11(5):e0154676, 2016.

| Newly deposited mouse strains

Dr. Akira ISHIKAWA, Nagoya University
RBRC09659 C57BL/6JJcl-Fap<em1Fjw>
RBRC09660 B6.Cg-Pbwg1/24Nga

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