{"id":6418,"date":"2009-04-30T14:37:11","date_gmt":"2009-04-30T05:37:11","guid":{"rendered":"http:\/\/mus.brc.riken.jp:7301\/?page_id=6418"},"modified":"2021-04-08T10:17:51","modified_gmt":"2021-04-08T01:17:51","slug":"apr_2009_mm","status":"publish","type":"page","link":"http:\/\/mus.brc.riken.jp\/en\/mouse_of_month\/apr_2009_mm","title":{"rendered":"Apr 2009  <em>A Japanese wild-derived inbred strain for functional genomics<\/em>"},"content":{"rendered":"<p><a title=\"Mouse of the Month archive\" href=\"\/en\/mouse_of_month\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-large wp-image-6421\" alt=\"mouse_of_month_200904\" src=\"\/en\/wp-content\/uploads\/2009\/04\/mouse_of_month_200904.png\" width=\"501\" height=\"84\" srcset=\"http:\/\/mus.brc.riken.jp\/en\/wp-content\/uploads\/2009\/04\/mouse_of_month_200904.png 501w, http:\/\/mus.brc.riken.jp\/en\/wp-content\/uploads\/2009\/04\/mouse_of_month_200904-150x25.png 150w, http:\/\/mus.brc.riken.jp\/en\/wp-content\/uploads\/2009\/04\/mouse_of_month_200904-400x67.png 400w\" sizes=\"auto, (max-width: 501px) 100vw, 501px\" \/><\/a><\/p>\n<table width=\"700\">\n<tbody>\n<tr>\n<td style=\"background-color: #ffffff; border: 0px;\">\n<h2 style=\"text-align: center;\"><strong><em>A Japanese wild-derived inbred strain for functional genomics<\/em><\/strong><\/h2>\n<h5 style=\"text-align: center;\"><strong><a href=\"https:\/\/brc.riken.jp\/mus\/RBRC00209\" target=\"_blank\" rel=\"noopener noreferrer\">MSM\/MsRbrc RBRC00209<\/a><\/strong><\/h5>\n<h5 style=\"text-align: center;\">Gen:F49 +F56<\/h5>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-6420\" alt=\"mn0904_0101\" src=\"\/en\/wp-content\/uploads\/2009\/04\/mn0904_0101.png\" width=\"340\" height=\"226\" srcset=\"http:\/\/mus.brc.riken.jp\/en\/wp-content\/uploads\/2009\/04\/mn0904_0101.png 340w, http:\/\/mus.brc.riken.jp\/en\/wp-content\/uploads\/2009\/04\/mn0904_0101-150x99.png 150w\" sizes=\"auto, (max-width: 340px) 100vw, 340px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-large wp-image-6422\" alt=\"mn0904_0102\" src=\"\/en\/wp-content\/uploads\/2009\/04\/mn0904_0102.png\" width=\"340\" height=\"252\" srcset=\"http:\/\/mus.brc.riken.jp\/en\/wp-content\/uploads\/2009\/04\/mn0904_0102.png 340w, http:\/\/mus.brc.riken.jp\/en\/wp-content\/uploads\/2009\/04\/mn0904_0102-150x111.png 150w\" sizes=\"auto, (max-width: 340px) 100vw, 340px\" \/><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<div style=\"width: 700px; text-align: left;\">\u00a0\u00a0MSM (RBRC00209) is a wild-derived inbred strain originated from Japanese wild mice,<em>Mus musculus molossinus<\/em>\u00a0[1]. The MSM mice have several unique phenotypes, such as small body size (&lt;15 grams), low incidence of tumor development, and distinct behaviors, making them promising resources for higher brain functions and lifestyle-related diseases by expanding genome diversity. The MSM is especially invaluable for uncovering novel functions of the genome by the availability of the MSM genomic BAC libraries [2], whole genome sequence information [3], microsatellite marker data [4], consomic strains with C57BL\/6 background [5], and germ cell competent ES cells [6]. Thus, the MSM expands the range of the genetic variations of laboratory mouse strains.\n<\/div>\n<p>&nbsp;<\/p>\n<table width=\"700\">\n<tbody>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left; white-space: nowrap;\" valign=\"top\">Depositor<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left; white-space: nowrap;\" valign=\"top\">:<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" colspan=\"2\" valign=\"top\"><a href=\"http:\/\/www.nig.ac.jp\/section\/shiroishi\/shiroishi-e.html\" target=\"_blank\" rel=\"noopener noreferrer\">Professor Toshihiko Shiroishi, Mammalian Genetics Laboratory, National Institute of Genetics, Mishima, Shizuoka-ken 411-8540, Japan.<\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left; white-space: nowrap;\" rowspan=\"6\" valign=\"top\">References<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left; white-space: nowrap;\" rowspan=\"6\" valign=\"top\">:<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\">1.<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\">Moriwaki, K.,\u00a0<em>et al.<\/em>\u00a02009.\u00a0<em><strong>Exp Anim.\u00a0<\/strong><\/em>58:123-134.<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\">2.<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=15574823\" target=\"_blank\" rel=\"noopener noreferrer\">Abe, K.,\u00a0<em>et al.\u00a0<\/em>2004.\u00a0<em><strong>Genome Research.\u00a0<\/strong><\/em>14: 2439-2447.<\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\">3.<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\"><a href=\"http:\/\/molossinus.lab.nig.ac.jp\/msmdb\/\" target=\"_blank\" rel=\"noopener noreferrer\">http:\/\/molossinus.lab.nig.ac.jp\/msmdb\/<\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\">4.<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\"><a href=\"http:\/\/www.shigen.nig.ac.jp\/mouse\/mmdbj\/top.jsp\" target=\"_blank\" rel=\"noopener noreferrer\">http:\/\/www.shigen.nig.ac.jp\/mouse\/mmdbj\/top.jsp<\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\">5.<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=18256237\" target=\"_blank\" rel=\"noopener noreferrer\">Takada, T.,\u00a0<em>et al.\u00a0<\/em>2008.\u00a0<em><strong>Genome Research.\u00a0<\/strong><\/em>18: 500-508.<\/a><br \/>\n<a href=\"http:\/\/molossinus.lab.nig.ac.jp\/phenotype\/index.html\" target=\"_blank\" rel=\"noopener noreferrer\">(http:\/\/molossinus.lab.nig.ac.jp\/phenotype\/index.html)<\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\">6.<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=19082856\" target=\"_blank\" rel=\"noopener noreferrer\">Araki, K.,\u00a0<em>et al.\u00a0<\/em>2009.\u00a0<em><strong>Mamm Genome.\u00a0<\/strong><\/em>20:14-20.<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>A Japanese wild-derived inbred strain for functional genomics MSM\/MsRbrc RBRC00209 Gen:F49 +F56 &nbsp; \u00a0\u00a0MSM (RBRC00209) is a wild-derived inbred strain originated from Japanese wild mice,Mus musculus molossinus\u00a0[1]. The MSM mice have several unique phenotypes, such as small body size (&lt;15 grams), low incidence of tumor development, and distinct behaviors, making them promising resources for higher brain functions and lifestyle-related diseases by expanding genome diversity. The MSM is especially invaluable for uncovering novel functions of the genome by the availability of the MSM genomic BAC libraries [2], whole genome sequence information [3], microsatellite marker data [4], consomic strains with C57BL\/6 background [5], and germ cell competent ES cells [6]. Thus, the MSM expands the range of the genetic variations of laboratory mouse strains. &nbsp; Depositor : Professor Toshihiko Shiroishi, Mammalian Genetics Laboratory, National Institute of Genetics, Mishima, Shizuoka-ken 411-8540, Japan. References : 1. Moriwaki, K.,\u00a0et al.\u00a02009.\u00a0Exp Anim.\u00a058:123-134. 2. Abe, K.,\u00a0et al.\u00a02004.\u00a0Genome Research.\u00a014: 2439-2447. 3. http:\/\/molossinus.lab.nig.ac.jp\/msmdb\/ 4. http:\/\/www.shigen.nig.ac.jp\/mouse\/mmdbj\/top.jsp 5. Takada, T.,\u00a0et al.\u00a02008.\u00a0Genome Research.\u00a018: 500-508. (http:\/\/molossinus.lab.nig.ac.jp\/phenotype\/index.html) 6. Araki, K.,\u00a0et al.\u00a02009.\u00a0Mamm Genome.\u00a020:14-20.<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":198,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":"","_wp_rev_ctl_limit":""},"class_list":["post-6418","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/mus.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/6418","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/mus.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/mus.brc.riken.jp\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/en\/wp-json\/wp\/v2\/comments?post=6418"}],"version-history":[{"count":10,"href":"http:\/\/mus.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/6418\/revisions"}],"predecessor-version":[{"id":18174,"href":"http:\/\/mus.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/6418\/revisions\/18174"}],"up":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/198"}],"wp:attachment":[{"href":"http:\/\/mus.brc.riken.jp\/en\/wp-json\/wp\/v2\/media?parent=6418"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}