{"id":11828,"date":"2014-11-25T11:20:20","date_gmt":"2014-11-25T02:20:20","guid":{"rendered":"http:\/\/mus0.mus.rbrc.jp\/?page_id=11828"},"modified":"2021-01-29T14:12:45","modified_gmt":"2021-01-29T05:12:45","slug":"nov_2014","status":"publish","type":"page","link":"http:\/\/mus.brc.riken.jp\/ja\/current_tech\/nov_2014","title":{"rendered":"BRC Current Technology November 2014"},"content":{"rendered":"<table style=\"max-width:700px;border:0px;\">\n<tbody>\n<tr>\n<td style=\"text-align: center; white-space: nowrap; position:absolute;border:0px;background-color:#fff;\">\n<img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/2013\/05\/brc_logo2.png\" alt=\"RIKEN BRC\"\/><\/td>\n<td style=\"text-align:center;border:0px;background-color:#fff;\"><a href=\"\/ja\/current_tech\" style=\"text-decoration: none;\"><br \/>\n<span style=\"color:#000000; font-size: 25pt; line-height: 130%; font-weight: bold;\">BRC Current Technology<\/span><br \/>\n<span style=\"color:#0000ff; font-size: 25pt; line-height: 130%; font-weight: bold;\">November 2014<\/span><\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"text-align: center;border:0px;background-color:#fff;\" colspan=\"2\">\n<h1 style=\"color: #0000ff;\">9. \u751f\u6b96\u7d30\u80de\u3092\u7528\u3044\u305f\u6838\u79fb\u690d<\/h1>\n<h2>\u767a\u751f\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u7814\u7a76\u3078\u306e\u5fdc\u7528<\/h2>\n<div style=\"text-align:center;\">\n<a href=\"\/ja\/wp-content\/uploads\/2014\/11\/current_tech_14111.png\"><img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/2014\/11\/current_tech_14111.png\" alt=\"dna methylation\" width=\"550\" height=\"\" \/><\/a>\n<\/div>\n<\/td>\n<\/tr>\n<tr>\n<td style=\"border:0px;background-color:#fff; white-space: normal; text-indent: 1em;\" colspan=\"2\">\u9664\u6838\uff08\u67d3\u8272\u4f53\u9664\u53bb\uff09\u5375\u5b50\u3078\u306e\u6838\u79fb\u690d\u306f\u3001\u30c9\u30ca\u30fc\u7d30\u80de\u306e\u907a\u4f1d\u60c5\u5831\u3092\u6301\u3064\u80da\u3092\u4f5c\u51fa\u3059\u308b\u6280\u8853\u3067\u3042\u308b\u3002\u6838\u79fb\u690d\u306b\u3088\u3063\u3066\u3001\u30c9\u30ca\u30fc\u6838\u306e\u30b2\u30ce\u30e0\u306f\u5927\u898f\u6a21\u306a\u518d\u30d7\u30ed\u30b0\u30e9\u30e0\u5316\uff08\u521d\u671f\u5316\uff09\u3092\u9032\u884c\u3055\u305b\u3001\u53d7\u7cbe\u5375\u30b2\u30ce\u30e0\u3068\u540c\u7b49\u306e\u5168\u80fd\u6027(totipotency)\u3092\u7372\u5f97\u3059\u308b\u3002\u3057\u304b\u3057\u3001\u751f\u6b96\u7d30\u80de\u306e\u767a\u751f\u904e\u7a0b\u3067\u30b2\u30ce\u30e0\u306b\u8a18\u9332\u3055\u308c\u305f\u4e00\u90e8\u306e\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u8a18\u61b6\u3001\u4f8b\u3048\u3070\u7247\u89aa\u6027\u8a18\u61b6\uff08\u30b2\u30ce\u30e0\u5237\u8fbc\u307f\uff09\u306f\u3001\u518d\u30d7\u30ed\u30b0\u30e9\u30e0\u5316\u3055\u308c\u305a\u306b\u518d\u69cb\u7bc9\u80da\u306b\u5f15\u304d\u7d99\u304c\u308c\u308b\u3002\u3053\u306e\u73fe\u8c61\u3092\u5229\u7528\u3057\u3066\u3001\u3055\u307e\u3056\u307e\u306a\u767a\u751f\u6bb5\u968e\u306e\u751f\u6b96\u7d30\u80de\u3092\u30c9\u30ca\u30fc\u7d30\u80de\u3068\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u3053\u308c\u3089\u306e\u30c9\u30ca\u30fc\u30b2\u30ce\u30e0\u306e\u8a18\u61b6\u304c\u5236\u5fa1\u3057\u3066\u3044\u308b\u80da\u3084\u80ce\u4ed4\u3092\u4f5c\u51fa\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3002\u3053\u308c\u3089\u306e\u80da\u3084\u80ce\u4ed4\u304b\u3089\u306f\u3001DNA\u30e1\u30c1\u30eb\u5316\u60c5\u5831\u306e\u307f\u306a\u3089\u305a\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u30d1\u30bf\u30fc\u30f3\u306e\u60c5\u5831\u3082\u5f97\u3089\u308c\u3001\u3057\u304b\u3082\u5358\u4e00\u30b2\u30ce\u30e0\u306b\u304a\u3051\u308b\u8907\u6570\u907a\u4f1d\u5b50\u306e\u52d5\u614b\u3092\u8abf\u3079\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3002\u3053\u306e\u3088\u3046\u306b\u3057\u3066\u5f97\u3089\u308c\u305f\u60c5\u5831\u306b\u3088\u3063\u3066\u3001\u521d\u671f\u59cb\u539f\u751f\u6b96\u7d30\u80de\uff08\u6700\u521d\u306b\u73fe\u308c\u308b\u751f\u6b96\u7d30\u80de\uff09\u306b\u304a\u3051\u308b\u80ce\u4ed4\u7d30\u80de\u7531\u6765\u306e\u30b2\u30ce\u30e0\u5237\u8fbc\u307f\u306e\u6d88\u53bb[1]\u3001\u524d\u7cbe\u539f\u7d30\u80de\u306b\u304a\u3051\u308b\u7236\u65b9\u30b2\u30ce\u30e0\u5237\u8fbc\u307f\u306e\u6210\u7acb[2]\u3001\u767a\u80b2\u5375\u5b50\u306b\u304a\u3051\u308b\u5237\u8fbc\u307f\u578bX\u67d3\u8272\u4f53\u4e0d\u6d3b\u5316\u306e\u30a4\u30f3\u30d7\u30ea\u30f3\u30c8\u306e\u6210\u7acb[3]\u306e\u7406\u89e3\u3092\u6df1\u3081\u308b\u3053\u3068\u304c\u53ef\u80fd\u3067\u3042\u308b\u3002\u6838\u79fb\u690d\u6280\u8853\u306f\u3001\u30af\u30ed\u30fc\u30f3\u52d5\u7269\u306e\u4f5c\u51fa\u3068\u3044\u3046\u5b9f\u7528\u7684\u306a\u5074\u9762\u306e\u307f\u306a\u3089\u305a\u3001\u767a\u751f\u904e\u7a0b\u306b\u304a\u3051\u308b\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u7814\u7a76\u306b\u3082\u5927\u3044\u306b\u5f79\u7acb\u3063\u3066\u3044\u308b\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<table style=\"max-width:700px;\">\n<tbody>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\">[1]<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11934847\" target=\"_blank\" rel=\"noopener noreferrer\">Lee J, Inoue K, Ono R, Ogonuki N, Kohda T, Kaneko-Ishino T, Ogura A, Ishino F.<br \/>\nDevelopment 129:1807-1817, 2002.<\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\">[2]<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25232016\" target=\"_blank\" rel=\"noopener noreferrer\">Kamimura S, Hatanaka Y, Hirasawa R, Matsumoto K, Oikawa M, Lee J, Matoba S, Mizutani E, Ogonuki N, Inoue K, Kohda T, Ishino F, Ogura A. Biol Reprod\u00a091:120,\u00a02014.<\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\">[3]<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\"><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24172050\" target=\"_blank\" rel=\"noopener noreferrer\">Oikawa M, Inoue K, Shiura H, Matoba S, Kamimura S, Hirose M, Mekada K, Yoshiki A, Tanaka S, Abe K, Ishino F, Ogura A. Epigenetics 9:204-211, 2014.<br \/>\n<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>BRC Current Technology November 2014 9. \u751f\u6b96\u7d30\u80de\u3092\u7528\u3044\u305f\u6838\u79fb\u690d \u767a\u751f\u30a8\u30d4\u30b8\u30a7\u30cd\u30c6\u30a3\u30af\u30b9\u7814\u7a76\u3078\u306e\u5fdc\u7528 \u9664\u6838\uff08\u67d3\u8272\u4f53\u9664\u53bb\uff09\u5375\u5b50\u3078\u306e\u6838\u79fb\u690d\u306f\u3001\u30c9\u30ca\u30fc\u7d30\u80de\u306e\u907a\u4f1d\u60c5\u5831\u3092\u6301\u3064\u80da\u3092\u4f5c\u51fa\u3059\u308b\u6280\u8853\u3067\u3042\u308b\u3002\u6838\u79fb\u690d\u306b\u3088\u3063\u3066\u3001\u30c9\u30ca\u30fc\u6838\u306e\u30b2\u30ce\u30e0\u306f\u5927\u898f\u6a21\u306a\u518d\u30d7\u30ed\u30b0\u30e9\u30e0\u5316\uff08\u521d\u671f\u5316\uff09\u3092\u9032\u884c\u3055\u305b\u3001\u53d7\u7cbe\u5375\u30b2\u30ce\u30e0\u3068\u540c\u7b49\u306e\u5168\u80fd\u6027(totipotency)\u3092\u7372\u5f97\u3059\u308b\u3002\u3057\u304b\u3057\u3001\u751f\u6b96\u7d30\u80de\u306e\u767a\u751f\u904e\u7a0b\u3067\u30b2\u30ce [&hellip;]<\/p>\n","protected":false},"author":19,"featured_media":0,"parent":3268,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_seopress_robots_follow":"","_seopress_robots_imageindex":"","_seopress_robots_snippet":"","_seopress_robots_primary_cat":"","_seopress_robots_breadcrumbs":"","_seopress_robots_freeze_modified_date":"","_seopress_robots_custom_modified_date":"","_seopress_robots_canonical":"","_seopress_social_fb_title":"","_seopress_social_fb_desc":"","_seopress_social_fb_img":"","_seopress_social_fb_img_attachment_id":0,"_seopress_social_fb_img_width":0,"_seopress_social_fb_img_height":0,"_seopress_social_twitter_title":"","_seopress_social_twitter_desc":"","_seopress_social_twitter_img":"","_seopress_social_twitter_img_attachment_id":0,"_seopress_social_twitter_img_width":0,"_seopress_social_twitter_img_height":0,"_seopress_redirections_value":"","_seopress_redirections_enabled":"","_seopress_redirections_enabled_regex":"","_seopress_redirections_logged_status":"","_seopress_redirections_param":"","_seopress_redirections_type":301,"_seopress_analysis_target_kw":"","footnotes":"","_wp_rev_ctl_limit":""},"class_list":["post-11828","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/11828","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/comments?post=11828"}],"version-history":[{"count":20,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/11828\/revisions"}],"predecessor-version":[{"id":17898,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/11828\/revisions\/17898"}],"up":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/3268"}],"wp:attachment":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/media?parent=11828"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}