{"id":18519,"date":"2021-11-01T10:12:12","date_gmt":"2021-11-01T01:12:12","guid":{"rendered":"http:\/\/mus.brc.riken.jp\/ja\/?page_id=18519"},"modified":"2021-11-01T10:18:03","modified_gmt":"2021-11-01T01:18:03","slug":"nov_2021_mm","status":"publish","type":"page","link":"http:\/\/mus.brc.riken.jp\/ja\/mouse_of_month\/nov_2021_mm","title":{"rendered":"3.0-Mb\u6b20\u5931\u3092\u518d\u73fe\u3057\u305f22q11.2\u6b20\u5931\u75c7\u5019\u7fa4\u30e2\u30c7\u30eb\u30de\u30a6\u30b9"},"content":{"rendered":"\n\n\n
\"RIKEN<\/td>\nNovember 2021<\/span>
\nMouse of the Month<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n
\n

3.0-Mb\u6b20\u5931\u3092\u518d\u73fe\u3057\u305f22q11.2\u6b20\u5931\u75c7\u5019\u7fa4\u30e2\u30c7\u30eb\u30de\u30a6\u30b9<\/span><\/p>\n

\nC57BL\/6N-Del(16Pi4ka-Hira)Atai (RBRC11066)<\/a>
\n<\/h5>\n

\n\"3.0-Mb\u6b20\u5931\u306e\u6982\u8981\"<\/a><\/p>\n

Courtesy of Atsu Aiba, Ph.D.<\/p>\n

22q11.2\u6b20\u5931\u75c7\u5019\u7fa43.0-Mb\u6b20\u5931\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u306e\u6982\u8981\u3002\u3053\u306e\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u3067\u306f22q11.2\u6b20\u5931\u75c7\u5019\u7fa4\u306e\u60a3\u8005\u3067\u898b\u3089\u308c\u308b3.0-Mb\u9818\u57df\u306e\u6b20\u5931\uff08\u9752\u8272\u306e\u7bc4\u56f2\uff09\u306b\u76f8\u5f53\u3059\u308b\u6b20\u5931\uff08\u8d64\u8272\u306e\u7bc4\u56f2\uff09\u3092\u518d\u73fe\u3057\u3066\u3044\u308b\u3002\n<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n
22q11.2\u6b20\u5931\u75c7\u5019\u7fa4\u306f\u30d2\u30c822\u756a\u67d3\u8272\u4f53\u9577\u7897(q)11.2\u9818\u57df\u306b\u5fae\u7d30\u6b20\u5931\u304c\u8a8d\u3081\u3089\u308c\u308b\u67d3\u8272\u4f53\u75be\u60a3\u3067\u3059\u30024,000\uff5e5,000\u4eba\u306b\uff11\u4eba\u306e\u983b\u5ea6\u3067\u767a\u75c7\u3059\u308b\u3068\u8a00\u308f\u308c\u3001\u305d\u306e\u3046\u3061\u6700\u3082\u4e3b\u8981\u306a\u30bf\u30a4\u30d7\u306f\u3001\u7279\u5b9a\u306e3.0Mb\u9818\u57df\u306e\u6b20\u5931\u3067\u3059\u3002\u3053\u306e\u9818\u57df\u306b\u306f\u300145\u500b\u306e\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0\u907a\u4f1d\u5b50\u304c\u5b58\u5728\u3057\u3001\u30de\u30a6\u30b916\u756a\u67d3\u8272\u4f53\u9577\u8155A13\u9818\u57df(Pi4ka<\/i>–Hira<\/i>\u9593)\u306b\u30b7\u30f3\u30c6\u30cb\u30fc\u3092\u6301\u3063\u305f\u307e\u307e\u4fdd\u5b58\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4eca\u56de\u3054\u7d39\u4ecb\u3059\u308b\u65b0\u898f22q11.2\u6b20\u5931\u75c7\u5019\u7fa4\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u306f\u3001\u3053\u306e3.0Mb\u9818\u57df\u6b20\u5931\u3092\u3001CRISPR\/Cas9\u30b7\u30b9\u30c6\u30e0\u3092\u7528\u3044\u305f\u30b2\u30ce\u30e0\u7de8\u96c6\u6cd5\u306b\u3088\u3063\u3066\u518d\u73fe\u3057\u305f\u7cfb\u7d71\u3067\u3059 (RBRC11066: Del(3.0Mb)\/+\u30de\u30a6\u30b9)\u3002
\n22q11.2\u6b20\u5931\u75c7\u5019\u7fa4\u3067\u306f\u3001\u5148\u5929\u6027\u5fc3\u75be\u60a3\u3001\u7279\u5fb4\u7684\u9854\u8c8c\u3092\u5408\u4f75\u3057\u3001\u80f8\u817a\u4f4e\u5f62\u6210\u30fb\u7121\u5f62\u6210\u306b\u3088\u308b\u514d\u75ab\u4f4e\u4e0b\u3001\u53e3\u84cb\u88c2\u30fb\u8edf\u53e3\u84cb\u9589\u9396\u4e0d\u5168\u3001\u9f3b\u58f0\u3001\u4f4e\u30ab\u30eb\u30b7\u30a6\u30e0\u8840\u75c7\u306a\u3069\u304c\u898b\u3089\u308c\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u5b9f\u969b\u306bDel(3.0Mb)\/+\u30de\u30a6\u30b9\u306e\u7d44\u7e54\u5b66\u7684\u89e3\u6790\u3092\u884c\u3063\u305f\u3068\u3053\u308d\u3001\u60a3\u8005\u3067\u898b\u3089\u308c\u308b\u3001\u5927\u52d5\u8108\u5f13\u96e2\u65ad\u3001\u53f3\u9396\u9aa8\u4e0b\u52d5\u8108\u8d77\u59cb\u7570\u5e38\u3001\u80f8\u817a\u4f4e\u5f62\u6210\u304c\u89b3\u5bdf\u3055\u308c\u307e\u3057\u305f\u3002
\n\u307e\u305f\u300122q11.2\u6b20\u5931\u75c7\u5019\u7fa4\u3067\u306f\u3001\u524d\u8ff0\u306e\u591a\u69d8\u306a\u81e8\u5e8a\u75c7\u72b6\u306b\u52a0\u3048\u3066\u3001\u7d71\u5408\u5931\u8abf\u75c7\u3001\u77e5\u7684\u969c\u5bb3\u306a\u3069\u3055\u307e\u3056\u307e\u306a\u7cbe\u795e\u75be\u60a3\u3084\u767a\u9054\u969c\u5bb3\u306e\u767a\u75c7\u30ea\u30b9\u30af\u3092\u9ad8\u3081\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u5b9f\u969b\u306bDel(3.0Mb)\/+\u30de\u30a6\u30b9\u306e\u884c\u52d5\u89e3\u6790\u3092\u884c\u3063\u305f\u3068\u3053\u308d\u3001\u30aa\u30fc\u30d7\u30f3\u30d5\u30a3\u30fc\u30eb\u30c9\u8a66\u9a13\u3068Y\u5b57\u578b\u8ff7\u8def\u8a66\u9a13\u306b\u304a\u3051\u308b\u6d3b\u52d5\u91cf\u30fb\u63a2\u7d22\u884c\u52d5\u306e\u4f4e\u4e0b\u3001\u793e\u4f1a\u7684\u76f8\u4e92\u4f5c\u7528\u8a66\u9a13\u306b\u304a\u3051\u308b\u65b0\u5947\u306e\u30de\u30a6\u30b9\u3068\u306e\u63a5\u89e6\u6642\u9593\u306e\u6e1b\u5c11\u3001\u6050\u6016\u6761\u4ef6\u4ed8\u3051\u8a18\u61b6\u5b66\u7fd2\u8a66\u9a13\u306b\u304a\u3051\u308b\u8a18\u61b6\u529b\u306e\u4f4e\u4e0b\u3001\u30d7\u30ec\u30d1\u30eb\u30b9\u6291\u5236\u306e\u4f4e\u4e0b\u30fb\u8996\u899a\u8a98\u767a\u96fb\u4f4d\u306e\u632f\u5e45\u4f4e\u4e0b\u3068\u3044\u3063\u305f\u7d71\u5408\u5931\u8abf\u75c7\u69d8\u306e\u8868\u73fe\u578b\u3092\u793a\u3057\u307e\u3057\u305f\u3002
\n\u7cbe\u795e\u75be\u60a3\u306e\u591a\u304f\u306f\u3001\u7f79\u60a3\u983b\u5ea6\u304c\u9ad8\u3044\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u9069\u3057\u305f\u52d5\u7269\u30e2\u30c7\u30eb\u304c\u5341\u5206\u5b58\u5728\u305b\u305a\u3001\u767a\u75c7\u30e1\u30ab\u30cb\u30ba\u30e0\u306e\u89e3\u660e\u3068\u3001\u305d\u308c\u306b\u57fa\u3065\u304f\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u304c\u78ba\u7acb\u3057\u3066\u3044\u306a\u3044\u306e\u304c\u73fe\u72b6\u3067\u3059\u3002\u4eca\u56de\u306eDel(3.0Mb)\/+\u30de\u30a6\u30b9\u306f\u3001\u7d71\u5408\u5931\u8abf\u75c7\u3092\u306f\u3058\u3081\u3068\u3059\u308b22q11.2\u6b20\u5931\u75c7\u5019\u7fa4\u3068\u95a2\u9023\u3059\u308b\u7cbe\u795e\u75be\u60a3\u306e\u7814\u7a76\u306b\u8ca2\u732e\u3059\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n\n\n\n
Depositor<\/td>\n:<\/td>\n\u9957\u5834 \u7be4 \u5148\u751f
\u6771\u4eac\u5927\u5b66\n<\/td>\n<\/tr>\n
Strain name<\/td>\n:<\/td>\nC57BL\/6N-Del(16Pi4ka-Hira)Atai\n<\/td>\n<\/tr>\n
RBRC No.<\/td>\n:<\/td>\nRBRC11066<\/td>\n<\/tr>\n
Reference<\/td>\n:<\/td>\n[1]<\/td>\nSaito R, Koebis M, Nagai T, Shimizu K, Liao J, Wulaer B, Sugaya Y, Nagahama K, Uesaka N, Kushima I, Mori D, Maruyama K, Nakao K, Kurihara H, Yamada K, Kano M, Fukada Y, Ozaki N, Aiba A.
\nComprehensive analysis of a novel mouse model of the 22q11.2 deletion syndrome: a model with the most common 3.0-Mb deletion at the human 22q11.2 locus.
\nTransl Psychiatry.<\/em> 2020 Feb 5;10(1):35.<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n
November 2021
\nSaori Mizuno, Ph.D.
\nContact: Experimental Animal Division, RIKEN BioResource Research Center (animal.brc@riken.jp)<\/a>
\nAll materials contained on this site may not be reproduced, distributed, displayed, published or broadcast without the prior permission of the owner of that content.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

November 2021 Mouse of the Month 3.0-Mb\u6b20\u5931\u3092\u518d\u73fe\u3057\u305f22q11.2\u6b20\u5931\u75c7\u5019\u7fa4\u30e2\u30c7\u30eb\u30de\u30a6\u30b9 C57BL\/6N-Del(16Pi4ka-Hira)Atai (RBRC11066) Courtesy of Atsu Aiba, Ph.D. 22q11.2\u6b20\u5931\u75c7\u5019\u7fa43.0-Mb\u6b20\u5931\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u306e\u6982\u8981\u3002\u3053\u306e\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u3067\u306f22q11.2\u6b20\u5931\u75c7\u5019\u7fa4\u306e\u60a3\u8005\u3067\u898b\u3089\u308c\u308b3.0 […]<\/p>\n","protected":false},"author":19,"featured_media":0,"parent":198,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_seopress_robots_follow":"","_seopress_robots_imageindex":"","_seopress_robots_snippet":"","_seopress_robots_primary_cat":"","_seopress_robots_breadcrumbs":"","_seopress_robots_freeze_modified_date":"","_seopress_robots_custom_modified_date":"","_seopress_robots_canonical":"","_seopress_social_fb_title":"","_seopress_social_fb_desc":"","_seopress_social_fb_img":"","_seopress_social_fb_img_attachment_id":0,"_seopress_social_fb_img_width":0,"_seopress_social_fb_img_height":0,"_seopress_social_twitter_title":"","_seopress_social_twitter_desc":"","_seopress_social_twitter_img":"","_seopress_social_twitter_img_attachment_id":0,"_seopress_social_twitter_img_width":0,"_seopress_social_twitter_img_height":0,"_seopress_redirections_value":"","_seopress_redirections_enabled":"","_seopress_redirections_enabled_regex":"","_seopress_redirections_logged_status":"","_seopress_redirections_param":"","_seopress_redirections_type":301,"_seopress_analysis_target_kw":"","footnotes":"","_wp_rev_ctl_limit":""},"class_list":["post-18519","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/18519","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/comments?post=18519"}],"version-history":[{"count":4,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/18519\/revisions"}],"predecessor-version":[{"id":18762,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/18519\/revisions\/18762"}],"up":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/198"}],"wp:attachment":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/media?parent=18519"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}