{"id":19506,"date":"2023-02-03T10:04:37","date_gmt":"2023-02-03T01:04:37","guid":{"rendered":"http:\/\/mus.brc.riken.jp\/ja\/?page_id=19506"},"modified":"2023-08-31T15:14:26","modified_gmt":"2023-08-31T06:14:26","slug":"feb_2023_mm","status":"publish","type":"page","link":"http:\/\/mus.brc.riken.jp\/ja\/mouse_of_month\/feb_2023_mm","title":{"rendered":"Gal4\/UAS\u767a\u73fe\u30b7\u30b9\u30c6\u30e0\u4f9d\u5b58\u7684\u306a\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u3068\u7d30\u80de\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u304c\u53ef\u80fd\u306a\u30de\u30a6\u30b9"},"content":{"rendered":"<table style=\"max-width:700px;\">\n<tbody>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: center; white-space: nowrap;\"  valign=\"middle\"><img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/2013\/05\/brc_logo2.png\" alt=\"RIKEN BRC\" width=\"36px\" height=\"74px\"\/><\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: center; valign=middle\"><a href=\"\/ja\/mouse_of_month#2023\" style=\"text-decoration: none;\"><span style=\"color:#0000ff; font-style: italic; font-family: Times New Roman; font-size: 25pt; line-height: 130%; font-weight: bold;\">February 2023<\/span><br \/>\n<span style=\"color:#000000; font-style: italic; font-family: Times New Roman; font-size: 25pt; line-height: 130%; font-weight: bold;\">Mouse of the Month<\/span><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"max-width:700px;\">\n<tbody>\n<tr>\n<td style=\"background-color: #ffffff; border: 0px; text-align: center;\">\n<p style=\"text-align:center;\"><span style=\"font-size: x-large; font-weight : bold; line-height: 130%;\">Gal4\/UAS\u767a\u73fe\u30b7\u30b9\u30c6\u30e0\u4f9d\u5b58\u7684\u306a<br \/>\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u3068\u7d30\u80de\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u304c\u53ef\u80fd\u306a\u30de\u30a6\u30b9<br \/>\n<\/span>\n    <\/p>\n<h5 style=\"text-align: center;\"><a href=\"https:\/\/brc.riken.jp\/mus\/RBRC11716\">Crl:CD1(ICR)-Tg(UAS-cre\/T2A\/miRFP670)216Staka (RBRC11716)<\/a><br \/>\n     <\/h5>\n<p style=\"text-align: center;\">\n      <a href=\"\/ja\/wp-content\/uploads\/2023\/02\/MMfig_202302.png\"><img decoding=\"async\" src=\"\/ja\/wp-content\/uploads\/2023\/02\/MMfig_202302\" alt=\"Notch1\u30b7\u30b0\u30ca\u30eb\u306e\u53ef\u8996\u5316\" width=\"600px\" height=\"\" \/><\/a>\n    <\/p>\n<p style=\"text-align:left; font-weight: bold;\">Notch1\u30b7\u30b0\u30ca\u30eb\u306fCre\u30ea\u30b3\u30f3\u30d3\u30ca\u30fc\u30bc\u3068miRFP670\u306e\u767a\u73fe\uff08\u3068\u3082\u306b\u9032\u884c\u4e2d\u306e\u30b7\u30b0\u30ca\u30eb\uff09\u3092\u8a98\u5c0e\u3059\u308b\u3002R26GRR\u30de\u30a6\u30b9\uff08RBRC04874\uff09\u3068\u7d44\u307f\u5408\u308f\u305b\u308b\u3068\u3001Cre\u30ea\u30b3\u30f3\u30d3\u30ca\u30fc\u30bc\u306b\u3088\u3063\u3066\u904e\u53bb\u306eNotch1\u30b7\u30b0\u30ca\u30eb\u304ctDsRed\u3067\u6a19\u8b58\u3055\u308c\u308b\uff08\u4e0a\u6bb5\uff09\u3002\u6d77\u99ac\u3084\u7db2\u819c\u3092\u542b\u3080\u795e\u7d4c\u7d44\u7e54\u306f\u3001Notch1\u30b7\u30b0\u30ca\u30eb\u3092\u53d7\u3051\u3064\u3064\u767a\u751f\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u308b\u3002UC2i\u30de\u30a6\u30b9\u3092\u542b\u3080\u4e0a\u8a18\u30de\u30a6\u30b9\u7cfb\u3067\u3001\u6d77\u99ac\u306b\u304a\u3051\u308b\u904e\u53bb\u306e\u3001\u305d\u3057\u3066\u3001\u767a\u751f\u4e2d\u306e\u7db2\u819c\u306b\u304a\u3051\u308b\u9032\u884c\u4e2d\u306eNotch1\u30b7\u30b0\u30ca\u30eb\u306e\u53ef\u8996\u5316\u306b\u6210\u529f\u3057\u305f\uff08\u4e0b\u6bb5\uff09\u3002\n    <\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"max-width:700px;\">\n<tbody>\n<tr>\n<td style=\"border: 5px; background-color: #ffffff; text-align: left; white-space: normal; text-indent: 1em;\" valign=\"top\">Gal4\/UAS\u767a\u73fe\u30b7\u30b9\u30c6\u30e0\u306f\u3001\u9175\u6bcd\u7531\u6765\u306e\u8ee2\u5199\u56e0\u5b50Gal4\u3068\u3001\u305d\u306e\u30a8\u30f3\u30cf\u30f3\u30b5\u30fc\u914d\u5217\u3067\u3042\u308bUAS\u306e\u7d50\u5408\u3092\u5229\u7528\u3057\u305f\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u8a98\u5c0e\u30b7\u30b9\u30c6\u30e0\u3067\u3059\u3002\u30b7\u30e7\u30a6\u30b8\u30e7\u30a6\u30d0\u30a8\u306a\u3069\u3067\u306f\u3088\u304f\u5229\u7528\u3055\u308c\u3066\u3044\u308b\u5b9f\u9a13\u7cfb\u3067\u3059\u3002\u4eca\u56de\u3054\u7d39\u4ecb\u3059\u308bUC2i\u30de\u30a6\u30b9(RBRC11716)\u306f\u3001<u>U<\/u>AS-<u>C<\/u>re-T<u>2<\/u>A-m<u>i<\/u>RFP670\u30c8\u30e9\u30f3\u30b9\u30b8\u30fc\u30f3\u306e\u633f\u5165\u306b\u3088\u308a\u3001Gal4\u4f9d\u5b58\u7684\u306bCre\u7d44\u307f\u63db\u3048\u9175\u7d20\u3068\u8fd1\u8d64\u5916\u86cd\u5149\u30bf\u30f3\u30d1\u30af\u8ceamiRFP670\u3092\u767a\u73fe\u3059\u308b\u30c8\u30e9\u30f3\u30b9\u30b8\u30a7\u30cb\u30c3\u30af\u30de\u30a6\u30b9\u3067\u3059\u3002Gal4\u306e\u767a\u73fe\u3092\u5236\u5fa1\u3059\u308b\u3053\u3068\u3067\u3001Cre\/loxP\u30b7\u30b9\u30c6\u30e0\u3092\u4ecb\u3057\u305f\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u3068\u3001\u975e\u4fb5\u8972\u7684\u306a<i>in vivo<\/i>\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u304c\u53ef\u80fd\u3067\u3059\u3002\u5b9f\u969b\u306b\u5bc4\u8a17\u8005\u306e\u9ad8\u6a4b\u5148\u751f\u3001\u5409\u539f\u5148\u751f\u3089\u306f\u3001UC2i\u30de\u30a6\u30b9\u3068\u3001Cre\u86cd\u5149\u30ec\u30dd\u30fc\u30bf\u30fcR26GRR\u30de\u30a6\u30b9(RBRC04874)\u3001\u7d30\u80de\u5185\u30c9\u30e1\u30a4\u30f3\u304cGal4\u306b\u7f6e\u63db\u3057\u305fNotch1\u53d7\u5bb9\u4f53\u3092\u767a\u73fe\u3059\u308b\u30c8\u30e9\u30f3\u30b9\u30b8\u30a7\u30cb\u30c3\u30af\u30de\u30a6\u30b9\u306e3\u3064\u3092\u639b\u3051\u5408\u308f\u305b\u3066\u3001\u4fee\u98feNotch1\u53d7\u5bb9\u4f53\u306b\u5185\u5728\u6027Notch1\u30ea\u30ac\u30f3\u30c9\u304c\u7d50\u5408\u3059\u308b\u3068\u3001Gal4\u304c\u7d30\u80de\u819c\u304b\u3089\u5207\u65ad\u3055\u308c\u3001Cre\u7d44\u307f\u63db\u3048\u9175\u7d20\u3068miRFP670\u3092\u767a\u73fe\u3059\u308b\u3053\u3068\u3092\u78ba\u8a8d\u3057\u3066\u3044\u307e\u3059\u3002\u52a0\u3048\u3066\u3001Cre\u30ec\u30dd\u30fc\u30bf\u30fc\u306b\u3088\u308b\u86cd\u5149\u767a\u73fe\u3068miRFP670\u306b\u3088\u308b\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u306b\u3088\u308a\u3001\u9032\u884c\u4e2d\u3068\u904e\u53bb\u306eNotch1\u30b7\u30b0\u30ca\u30eb\u306e\u7d30\u80de\u30ec\u30d9\u30eb\u3067\u306e\u53ef\u8996\u5316\u3092\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<br \/>\n\u3053\u308c\u307e\u3067\u3001\u7d30\u80de\u52d5\u614b\u306e\u89e3\u6790\u3068\u3044\u3046\u9762\u3067\u306f\u3001Cre\u7d44\u307f\u63db\u3048\u9175\u7d20\u3084\u86cd\u5149\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3001\u8ee2\u5199\u56e0\u5b50\u767a\u73fe\u306e\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u306b\u5229\u7528\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001UC2i\u30de\u30a6\u30b9\u306f\u3001\u69d8\u3005\u306aGal4\u767a\u73fe\u30de\u30a6\u30b9\u3068\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u9593\u76f8\u4e92\u4f5c\u7528\u3092\u53ef\u8996\u5316\u3059\u308b\u3053\u3068\u3082\u3067\u304d\u307e\u3059\u3002\u4eca\u5f8c\u3001\u767a\u751f\u751f\u7269\u5b66\u5206\u91ce\u3092\u306f\u3058\u3081\u3001\u5e45\u5e83\u3044\u5206\u91ce\u3067\u306e\u5fdc\u7528\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002\n   <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<table style=\"max-width:700px;\">\n<tbody>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: right; white-space: nowrap;\" valign=\"top\">Keywords<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: center; white-space: nowrap;\" valign=\"top\">:<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" colspan=\"2\" valign=\"top\">Gal4\/UAS\u3001Cre\/loxP\u3001miRFP670\u3001<i>in vivo<\/i>\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u9593\u76f8\u4e92\u4f5c\u7528<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: right; white-space: nowrap;\" valign=\"top\">Depositor<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: center; white-space: nowrap;\" valign=\"top\">:<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left; font-weight: bold;\" colspan=\"2\" valign=\"top\">\u9ad8\u6a4b \u667a \u5148\u751f\u30fb\u5409\u539f \u96c5\u5927 \u5148\u751f<br \/>\u7b51\u6ce2\u5927\u5b66<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: right; white-space: nowrap;\" valign=\"top\">Strain name<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: center; white-space: nowrap;\" valign=\"top\">:<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left; font-weight: bold;\" colspan=\"2\" valign=\"top\">Crl:CD1(ICR)-Tg(UAS-cre\/T2A\/miRFP670)216Staka<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: right; white-space: nowrap;\" valign=\"top\">RBRC No.<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: center; white-space: nowrap;\" valign=\"top\">:<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" colspan=\"2\" valign=\"top\">RBRC11716<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: right; white-space: nowrap;\" valign=\"top\">Reference<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: center; white-space: nowrap;\" valign=\"top\">:<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\" valign=\"top\">Yoshihara M, Nishino T, Sambe N, Nayakama T, Radtke F, Mizuno S, Takahashi S.<br \/>\nGeneration of a Gal4-dependent gene recombination and illuminating mouse.<br \/>\n<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35444103\"><em>Exp Anim<\/em>. 2022 Aug 5;71(3):385-390.<\/a>\n   <\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: right; white-space: nowrap;\" valign=\"top\">Related strain<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: center; white-space: nowrap;\" valign=\"top\">:<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left; font-weight: bold;\" colspan=\"2\" valign=\"top\">C57BL\/6N-Gt(ROSA)26Sor&lt;tm1(CAG-EGFP\/DsRed)Utr&gt;\/Rbrc (RBRC04874)<\/td>\n<\/tr>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: right; white-space: nowrap;\" valign=\"top\">Related archives<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: center; white-space: nowrap;\" valign=\"top\">:<\/td>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left; font-weight: bold;\" colspan=\"2\" valign=\"top\"><a href=\"\/ja\/mouse_of_month\/Oct_2018_mm\">Mouse of the Month October 2018<\/a><br \/><a href=\"\/ja\/mouse_of_month\/mar_2014_mm\">Mouse of the Month March 2014<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<table class=\"w7\" frame=\"hsides\" cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td style=\"border: 0px; background-color: #ffffff; text-align: left;\">February 2023<br \/>\nSaori Mizuno, Ph.D.<br \/>\nContact: <a href=\"mailto:animal.brc@riken.jp\">Experimental Animal Division, RIKEN BioResource Research Center (animal.brc@riken.jp)<\/a><br \/>\nAll materials contained on this site may not be reproduced, distributed, displayed, published or broadcast without the prior permission of the owner of that content.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>February 2023 Mouse of the Month Gal4\/UAS\u767a\u73fe\u30b7\u30b9\u30c6\u30e0\u4f9d\u5b58\u7684\u306a\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u3068\u7d30\u80de\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u304c\u53ef\u80fd\u306a\u30de\u30a6\u30b9 Crl:CD1(ICR)-Tg(UAS-cre\/T2A\/miRFP670)216Staka (RBRC11716) Notch1\u30b7\u30b0\u30ca\u30eb\u306fCre\u30ea\u30b3\u30f3\u30d3\u30ca\u30fc\u30bc\u3068miRFP670\u306e\u767a\u73fe\uff08\u3068\u3082\u306b\u9032\u884c\u4e2d\u306e\u30b7\u30b0\u30ca\u30eb\uff09\u3092\u8a98\u5c0e\u3059\u308b\u3002R26GRR\u30de\u30a6\u30b9\uff08RBRC0 [&hellip;]<\/p>\n","protected":false},"author":19,"featured_media":0,"parent":198,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_seopress_robots_follow":"","_seopress_robots_imageindex":"","_seopress_robots_snippet":"","_seopress_robots_primary_cat":"","_seopress_robots_breadcrumbs":"","_seopress_robots_freeze_modified_date":"","_seopress_robots_custom_modified_date":"","_seopress_robots_canonical":"","_seopress_social_fb_title":"","_seopress_social_fb_desc":"","_seopress_social_fb_img":"","_seopress_social_fb_img_attachment_id":0,"_seopress_social_fb_img_width":0,"_seopress_social_fb_img_height":0,"_seopress_social_twitter_title":"","_seopress_social_twitter_desc":"","_seopress_social_twitter_img":"","_seopress_social_twitter_img_attachment_id":0,"_seopress_social_twitter_img_width":0,"_seopress_social_twitter_img_height":0,"_seopress_redirections_value":"","_seopress_redirections_enabled":"","_seopress_redirections_enabled_regex":"","_seopress_redirections_logged_status":"both","_seopress_redirections_param":"","_seopress_redirections_type":301,"_seopress_analysis_target_kw":"","footnotes":"","_wp_rev_ctl_limit":""},"class_list":["post-19506","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/19506","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/comments?post=19506"}],"version-history":[{"count":2,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/19506\/revisions"}],"predecessor-version":[{"id":19828,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/19506\/revisions\/19828"}],"up":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/198"}],"wp:attachment":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/media?parent=19506"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}