{"id":21086,"date":"2026-08-04T14:40:00","date_gmt":"2026-08-04T05:40:00","guid":{"rendered":"http:\/\/mus.brc.riken.jp\/ja\/?page_id=21086"},"modified":"2026-08-04T14:40:00","modified_gmt":"2026-08-04T05:40:00","slug":"aug_2026_mm","status":"publish","type":"page","link":"http:\/\/mus.brc.riken.jp\/ja\/mouse_of_month\/aug_2026_mm","title":{"rendered":"\u30ab\u30eb\u30b7\u30c8\u30cb\u30f3\u53d7\u5bb9\u4f53Cre\u30c9\u30e9\u30a4\u30d0\u30fc\u30de\u30a6\u30b9"},"content":{"rendered":"\n\n\n\n\n\n\n
\"RIKEN<\/td>\nAugust 2026<\/span>
\nMouse of the Month<\/span><\/a><\/td>\n<\/tr>\n<\/thead>\n
\n

\u30ab\u30eb\u30b7\u30c8\u30cb\u30f3\u53d7\u5bb9\u4f53Cre\u30c9\u30e9\u30a4\u30d0\u30fc\u30de\u30a6\u30b9<\/p>\n

C57BL\/6-Tg(Calcr-cre)1Oyak (RBRC11708)<\/a>
\n<\/h5>\n

\"\u5b50\u80b2\u3066\u884c\u52d5\u306e\u795e\u7d4c\u6a5f\u69cb\"<\/a>\n <\/p>\n<\/td>\n<\/td>\n<\/tr>\n<\/tbody>\n

\u5bc4\u8a17\u8005\u306e\u9ed2\u7530\u516c\u7f8e\u5148\u751f\u3089\u306f\u30012013\u5e74\u306b\u3001\u30de\u30a6\u30b9\u306e\u5b50\u80b2\u3066\u884c\u52d5\u306b\u5fc5\u9808\u306e\u8133\u9818\u57df\u3068\u3057\u3066\u3001\u5185\u5074\u8996\u7d22\u524d\u91ce\u4e2d\u592e\u90e8\uff08Medial preoptic area; MPOA\uff09\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002MPOA\u306e\u6a5f\u80fd\u304c\u4f4e\u4e0b\u3059\u308b\u3068\u3001\u5b50\u80b2\u3066\u610f\u6b32\u304c\u9ad8\u3044\u3001\u51fa\u7523\u30fb\u5b50\u80b2\u3066\u7d4c\u9a13\u306e\u3042\u308b\u6bcd\u89aa\u30de\u30a6\u30b9\u3067\u3042\u3063\u3066\u3082\u3001\u5b50\u80b2\u3066\u3092\u3057\u306a\u304f\u306a\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059[1]\u3002\u3053\u306e\u6642\u70b9\u3067\u306f\u3001MPOA\u306b\u306f7\u7a2e\u985e\u4ee5\u4e0a\u306e\u795e\u7d4c\u7d30\u80de\u96c6\u56e3\u304c\u5b58\u5728\u3059\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u3069\u306e\u7d30\u80de\u96c6\u56e3\u304c\u5b50\u80b2\u3066\u884c\u52d5\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u62c5\u3046\u306e\u304b\u306f\u5206\u304b\u3063\u3066\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u305d\u306e\u5f8c\u30012021\u5e74\u306b\u3001\u30ab\u30eb\u30b7\u30c8\u30cb\u30f3\u53d7\u5bb9\u4f53\uff08Calcr\uff09\u3068\u305d\u306e\u30ea\u30ac\u30f3\u30c9\u3067\u3042\u308b\u30a2\u30df\u30ea\u30f3\u304c\u3001MPOA\u5185\u306e\u7570\u306a\u308b\u795e\u7d4c\u7d30\u80de\u96c6\u56e3\u3067\u767a\u73fe\u3057\u3001\u7279\u306b\u6bcd\u30de\u30a6\u30b9\u306b\u304a\u3044\u3066\u305d\u306e\u767a\u73fe\u304c\u4ea2\u9032\u3059\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002Calcr\u3068\u30a2\u30df\u30ea\u30f3\u306f\u3001\u3044\u305a\u308c\u3082\u51fa\u7523\u5f8c\u306b\u767a\u73fe\u304c\u8457\u3057\u304f\u4e0a\u6607\u3057\u307e\u3059[2,3]\u3002\u3055\u3089\u306b\u30012025\u5e74\u306b\u306f\u3001\u795e\u7d4c\u7d30\u80de\u96c6\u56e3\u306e\u6d3b\u52d5\u3092\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u3067\u8a08\u6e2c\u30fb\u89e3\u6790\u3059\u308b\u751f\u4f53\u5185\u30d5\u30a1\u30a4\u30d0\u30fc\u30d5\u30a9\u30c8\u30e1\u30c8\u30ea\u30fc\u6cd5\u3092\u7528\u3044\u3066\u3001\u89aa\u548c\u7684\u793e\u4f1a\u884c\u52d5\u4e2d\u306eMPOA Calcr\u967d\u6027\u30cb\u30e5\u30fc\u30ed\u30f3\u306e\u6d3b\u52d5\u3092\u89e3\u6790\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u53d7\u52d5\u7684\u306a\u63a5\u89e6\u6642\u3084\u975e\u793e\u4f1a\u7684\u306a\u5bfe\u8c61\u3068\u306e\u63a5\u89e6\u6642\u306b\u306fCalcr\u967d\u6027\u30cb\u30e5\u30fc\u30ed\u30f3\u306f\u6d3b\u6027\u5316\u305b\u305a\u3001\u4ed6\u306e\u6210\u4f53\u96cc\u30de\u30a6\u30b9\u3068\u306e\u80fd\u52d5\u7684\u306a\u63a5\u89e6\u6642\u3084\u5b50\u30de\u30a6\u30b9\u306e\u56de\u53ce\u6642\u3068\u3044\u3063\u305f\u3001\u81ea\u767a\u7684\u306a\u52d5\u6a5f\u306b\u57fa\u3065\u304f\u4ed6\u8005\u3078\u306e\u884c\u52d5\u306b\u304a\u3044\u3066\u3001\u9078\u629e\u7684\u306b\u6d3b\u6027\u5316\u3059\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f[4]\u3002
\n\u7406\u7814BRC\u304b\u3089\u306f\u3001\u30de\u30a6\u30b9\u30ab\u30eb\u30b7\u30c8\u30cb\u30f3\u53d7\u5bb9\u4f53(Calcr)\u907a\u4f1d\u5b50\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\u306e\u4e0b\u6d41\u306b\u3001Cre\u7d44\u307f\u63db\u3048\u9175\u7d20\u907a\u4f1d\u5b50\u3092\u6301\u3064Cre\u30c9\u30e9\u30a4\u30d0\u30fc\u30de\u30a6\u30b9(RBRC11708: C57BL\/6-Tg(Calcr-cre)1Oyak)\u3092\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059\u3002\u30de\u30a6\u30b9\u3067\u660e\u3089\u304b\u306b\u306a\u308a\u3064\u3064\u3042\u308bMPOA\u3067\u306eCalcr\u306e\u6a5f\u80fd\u304c\u3001\u30d2\u30c8\u306b\u304a\u3044\u3066\u3082\u4fdd\u5b58\u3055\u308c\u3066\u3044\u308b\u304b\u304c\u4eca\u5f8c\u660e\u3089\u304b\u306b\u306a\u308b\u3053\u3068\u3067\u3001\u30d2\u30c8\u306b\u304a\u3051\u308b\u7d30\u80de\u30fb\u5206\u5b50\u30ec\u30d9\u30eb\u3067\u306e\u7406\u89e3\u304c\u9032\u307f\u3001\u5c06\u6765\u7684\u306b\u306f\u80b2\u5150\u884c\u52d5\u3084\u793e\u4f1a\u884c\u52d5\u306e\u7406\u89e3\u3001\u3055\u3089\u306b\u306f\u95a2\u9023\u3059\u308b\u75be\u60a3\u306e\u7814\u7a76\u3084\u533b\u7642\u3078\u306e\u5fdc\u7528\u306b\u3064\u306a\u304c\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002\n <\/td>\n<\/tr>\n<\/tfoot>\n<\/table>\n

 <\/p>\n\n\n\n\n\n\n\n\n\n\n
Keywords<\/td>\n:<\/td>\n\u30ab\u30eb\u30b7\u30c8\u30cb\u30f3\u53d7\u5bb9\u4f53\u3001\u5185\u5074\u8996\u7d22\u524d\u91ce\u4e2d\u592e\u90e8\u3001\u6bcd\u6027\u884c\u52d5\u3001\u990a\u80b2\u884c\u52d5\u3001\u793e\u4f1a\u7684\u63a5\u89e6<\/td>\n<\/tr>\n
Depositor<\/td>\n:<\/td>\n\u9ed2\u7530\u516c\u7f8e\u5148\u751f (\u5bc4\u8a17\u5f53\u6642\u30fb\u7406\u5316\u5b66\u7814\u7a76\u6240)<\/td>\n<\/tr>\n
Strain name<\/td>\n:<\/td>\nC57BL\/6-Tg(Calcr-cre)1Oyak<\/td>\n<\/tr>\n
RBRC No.<\/td>\n:<\/td>\nRBRC11708<\/td>\n<\/tr>\n
References<\/td>\n:<\/td>\n[1]<\/td>\nTsuneoka Y, Maruyama T, Yoshida S, Nishimori K, Kato T, Numan M, Kuroda KO.
\nFunctional, anatomical, and neurochemical differentiation of medial preoptic area subregions in relation to maternal behavior in the mouse.
\nJ Comp Neurol. 2013 May 1;521(7):1633-63.<\/a>\n <\/td>\n<\/tr>\n
[2]<\/td>\nYoshihara C, Tokita K, Maruyama T, Kaneko M, Tsuneoka Y, Fukumitsu K, Miyazawa E, Shinozuka K, Huang AJ, Nishimori K, McHugh TJ, Tanaka M, Itohara S, Touhara K, Miyamichi K, Kuroda KO.
\nCalcitonin receptor signaling in the medial preoptic area enables risk-taking maternal care.
\nCell Rep. 2021 Jun 1;35(9):109204.<\/a>\n <\/td>\n<\/tr>\n
[3]<\/td>\n\u5371\u967a\u3092\u5192\u3057\u3066\u5b50\u3092\u52a9\u3051\u308b\u89aa\u306e\uff0d\u5b50\u80b2\u3066\u306b\u5fc5\u9808\u306e\u8133\u5185\u5206\u5b50\u795e\u7d4c\u56de\u8def\u3092\u540c\u5b9a\uff0d
\n2021\u5e746\u67082\u65e5\u7406\u5316\u5b66\u7814\u7a76\u6240\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9<\/a>\n <\/td>\n<\/tr>\n
[4]<\/td>\nFukumitsu K, Yoshihara C, Huang AJ, McHugh TJ, Kuroda KO.
\nIn vivo recording from calcitonin receptor-expressing neurons in the medial preoptic area during affiliative social behaviors.
\nNeurosci Res. 2025 Jul:216:104878.<\/a>\n <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n\n\n\n
August 2026
\nSaori Mizuno, Ph.D.
\nContact: Experimental Animal Division, RIKEN BioResource Research Center (animal.brc@riken.jp)<\/a>
\nAll materials contained on this site may not be reproduced, distributed, displayed, published or broadcast without the prior permission of the owner of that content.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":19,"featured_media":0,"parent":198,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_seopress_robots_follow":"","_seopress_robots_imageindex":"","_seopress_robots_snippet":"","_seopress_robots_primary_cat":"","_seopress_robots_breadcrumbs":"","_seopress_robots_freeze_modified_date":"","_seopress_robots_custom_modified_date":"","_seopress_robots_canonical":"","_seopress_social_fb_title":"","_seopress_social_fb_desc":"","_seopress_social_fb_img":"","_seopress_social_fb_img_attachment_id":0,"_seopress_social_fb_img_width":0,"_seopress_social_fb_img_height":0,"_seopress_social_twitter_title":"","_seopress_social_twitter_desc":"","_seopress_social_twitter_img":"","_seopress_social_twitter_img_attachment_id":0,"_seopress_social_twitter_img_width":0,"_seopress_social_twitter_img_height":0,"_seopress_redirections_value":"","_seopress_redirections_enabled":"","_seopress_redirections_enabled_regex":"","_seopress_redirections_logged_status":"","_seopress_redirections_param":"","_seopress_redirections_type":0,"_seopress_analysis_target_kw":"","footnotes":"","_wp_rev_ctl_limit":""},"class_list":["post-21086","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/21086","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/comments?post=21086"}],"version-history":[{"count":1,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/21086\/revisions"}],"predecessor-version":[{"id":21087,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/21086\/revisions\/21087"}],"up":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/198"}],"wp:attachment":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/media?parent=21086"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}