{"id":6564,"date":"2007-07-31T16:28:08","date_gmt":"2007-07-31T07:28:08","guid":{"rendered":"http:\/\/mus.brc.riken.jp:7301\/?page_id=6564"},"modified":"2022-07-08T14:43:26","modified_gmt":"2022-07-08T05:43:26","slug":"jul_2007_mm","status":"publish","type":"page","link":"http:\/\/mus.brc.riken.jp\/ja\/mouse_of_month\/jul_2007_mm","title":{"rendered":"p38\u03b1 floxed mouse"},"content":{"rendered":"\n\n\n
\"RIKEN<\/td>\nJuly 2007<\/span>
\nMouse of the Month<\/span><\/a>\n <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n
\n p38\u03b1 floxed mouse
\nFor research in stress response pathways<\/span><\/p>\n
\n BRC No. 02192 B6.129-Mapk14<\/a>
\n Research Application : Signal transduction research<\/h5>\n

\"mn0707_0101\"
\n BRC No. 02192 B6.129-Mapk14\n <\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

\u00a0\u00a0Mitogen-activated protein (MAP) kinase cascades are highly conserved signal transduction pathways involved in a variety of physiological events. The MAP kinase family consists of extracellular signal-regulated protein kinase (ERK), c-Jun NH2-terminal protein kinase (JNK), and p38 MAP kinase. p38\u03b1, one of the p38 MAP kinase subfamily, is widely expressed and has an important function in cytokine production and the response to many types of stress. Because p38\u03b1-deficient mice (BRC No. 00361 C57BL\/6-TgH(p38)\/118<\/a>) showed embryonic lethality at midgestation, this strain is useful for the research of p38 MAP kinase pathway in various tissues using Cre-loxP system.\n<\/div>\n

 <\/p>\n\n\n\n\n
Depositor<\/td>\n:<\/td>\n\u00a0Dr. Kinya Otsu
\n(Osaka University)<\/a><\/td>\n<\/tr>\n
References<\/td>\n:<\/td>\nMol Cell Biol<\/i>\u00a02004 Dec;24(24):10611-10620.<\/a>\u00a0
\nJ Biol Chem<\/i>\u00a02002 Oct 4;277(40):37896-903. Epub 2002 Jul 22.<\/a>\u00a0
\nCell<\/i>\u00a02000 Jul 21;102(2):221-231.<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

July 2007 Mouse of the Month p38\u03b1 floxed mouse For research in stress response pathways BRC No. 02192 B6.129-Mapk14 Research Application : Signal transduction research BRC No. 02192 B6.129-Mapk14 &nbs […]<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":198,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_seopress_robots_follow":"","_seopress_robots_imageindex":"","_seopress_robots_snippet":"","_seopress_robots_primary_cat":"","_seopress_robots_breadcrumbs":"","_seopress_robots_freeze_modified_date":"","_seopress_robots_custom_modified_date":"","_seopress_robots_canonical":"","_seopress_social_fb_title":"","_seopress_social_fb_desc":"","_seopress_social_fb_img":"","_seopress_social_fb_img_attachment_id":0,"_seopress_social_fb_img_width":0,"_seopress_social_fb_img_height":0,"_seopress_social_twitter_title":"","_seopress_social_twitter_desc":"","_seopress_social_twitter_img":"","_seopress_social_twitter_img_attachment_id":0,"_seopress_social_twitter_img_width":0,"_seopress_social_twitter_img_height":0,"_seopress_redirections_value":"","_seopress_redirections_enabled":"","_seopress_redirections_enabled_regex":"","_seopress_redirections_logged_status":"both","_seopress_redirections_param":"","_seopress_redirections_type":301,"_seopress_analysis_target_kw":"","footnotes":"","_wp_rev_ctl_limit":""},"class_list":["post-6564","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/6564","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/comments?post=6564"}],"version-history":[{"count":8,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/6564\/revisions"}],"predecessor-version":[{"id":19130,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/6564\/revisions\/19130"}],"up":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/198"}],"wp:attachment":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/media?parent=6564"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}