{"id":6653,"date":"2006-07-01T14:23:58","date_gmt":"2006-07-01T05:23:58","guid":{"rendered":"http:\/\/mus.brc.riken.jp:7301\/?page_id=6653"},"modified":"2022-07-08T13:29:12","modified_gmt":"2022-07-08T04:29:12","slug":"jul_2006_mm","status":"publish","type":"page","link":"http:\/\/mus.brc.riken.jp\/ja\/mouse_of_month\/jul_2006_mm","title":{"rendered":"Cre Transgenic Mouse Series_2"},"content":{"rendered":"\n\n\n
\"RIKEN<\/td>\nJuly 2006<\/span>
\nMouse of the Month<\/span><\/a>\n <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n\n\n
\n Cre Transgenic Mouse Series_2<\/span>\n<\/td>\n<\/tr>\n
Cre recombinase is a 38 kDa enzyme derived from the bacteriophage P1 which specifically recognizes 34 bp loxP sites. Cre has been shown to effectively mediate the excision of DNA flanked by loxP sites. Cre-loxP system is a very useful tool for time-space-specific knock-out the genes which can not be investigated in adults because of their embryonic lethality in conventional gene-targetting.<\/td>\n<\/tr>\n
\"mn0607_0101\"
\nP7 seminiferous tubules.
\nBlue, recombined spermatogonia.<\/td>\n		\n\n\n\n\n\n\n\n\n\n\n\n
\n
Ngn3-Cre<\/b><\/span><\/h5>\n<\/td>\n<\/tr>\n
Promoter<\/b><\/td>\n:<\/b><\/td>\nNeurogenin 3<\/td>\n<\/tr>\n
Application<\/b><\/td>\n:<\/b><\/td>\nDevelopmental Biology<\/td>\n<\/tr>\n
Expression<\/b><\/td>\n:<\/b><\/td>\nSpermatogenesis (spermatogonia) Pancreatic\/enteric endocrine precursors<\/td>\n<\/tr>\n
Depositor<\/b><\/td>\n:<\/b><\/td>\nDr. Shosei Yoshida (Kyoto University)<\/td>\n<\/tr>\n
References<\/b><\/td>\n:<\/b><\/td>\nDev. Biol. 269, 447 (2004)<\/a>
\nDevelopment 133, 1495 (2006)<\/a><\/td>\n<\/tr>\n
BRC No. 01456 ngn3\/Cre transgenic mouse<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n
<\/td>\n<\/tr>\n
\"mn0607_0102\"<\/td>\n\n\n\n\n\n\n\n\n\n\n\n
\n
Olig2-CreER*<\/sup><\/b><\/span><\/h5>\n<\/td>\n<\/tr>\n
Promoter<\/b><\/td>\n:<\/b><\/td>\nOlig2<\/td>\n<\/tr>\n
Application<\/b><\/td>\n:<\/b><\/td>\nNeurobiology<\/td>\n<\/tr>\n
Expression<\/b><\/td>\n:<\/b><\/td>\nMotoneuron and Oligodendrocyte progenitors<\/td>\n<\/tr>\n
Depositor<\/b><\/td>\n:<\/b><\/td>\nDr. Hirohide Takebayashi (National Institute for Physiological Sciences)<\/td>\n<\/tr>\n
References<\/b><\/td>\n:<\/b><\/td>\nCurr. Biol.12, 1157 (2002)<\/a>
\nDev. Biol. 293, 358 (2006)<\/a><\/td>\n<\/tr>\n
BRC No. 01507 Olig2-CreER knock in mouse<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n
\u00a0*<\/sup>CreER is tamoxifen-inducible Cre recombinase\/Estrogen receptor fusion protein.To See other Cre transgenic mice<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

July 2006 Mouse of the Month Cre Transgenic Mouse Series_2 Cre recombinase is a 38 kDa enzyme derived from the bacteriophage P1 which specifically recognizes 34 bp loxP sites. Cre has been shown to ef […]<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":198,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_seopress_robots_follow":"","_seopress_robots_imageindex":"","_seopress_robots_snippet":"","_seopress_robots_primary_cat":"","_seopress_robots_breadcrumbs":"","_seopress_robots_freeze_modified_date":"","_seopress_robots_custom_modified_date":"","_seopress_robots_canonical":"","_seopress_social_fb_title":"","_seopress_social_fb_desc":"","_seopress_social_fb_img":"","_seopress_social_fb_img_attachment_id":0,"_seopress_social_fb_img_width":0,"_seopress_social_fb_img_height":0,"_seopress_social_twitter_title":"","_seopress_social_twitter_desc":"","_seopress_social_twitter_img":"","_seopress_social_twitter_img_attachment_id":0,"_seopress_social_twitter_img_width":0,"_seopress_social_twitter_img_height":0,"_seopress_redirections_value":"","_seopress_redirections_enabled":"","_seopress_redirections_enabled_regex":"","_seopress_redirections_logged_status":"both","_seopress_redirections_param":"","_seopress_redirections_type":301,"_seopress_analysis_target_kw":"","footnotes":"","_wp_rev_ctl_limit":""},"class_list":["post-6653","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/6653","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/comments?post=6653"}],"version-history":[{"count":12,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/6653\/revisions"}],"predecessor-version":[{"id":19104,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/6653\/revisions\/19104"}],"up":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/198"}],"wp:attachment":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/media?parent=6653"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}