{"id":6665,"date":"2006-06-01T15:38:10","date_gmt":"2006-06-01T06:38:10","guid":{"rendered":"http:\/\/mus.brc.riken.jp:7301\/?page_id=6665"},"modified":"2022-07-08T13:28:10","modified_gmt":"2022-07-08T04:28:10","slug":"jun_2006_mm","status":"publish","type":"page","link":"http:\/\/mus.brc.riken.jp\/ja\/mouse_of_month\/jun_2006_mm","title":{"rendered":"Cre Transgenic Mouse Series_1"},"content":{"rendered":"\n\n\n
\"RIKEN<\/td>\nJune 2006<\/span>
\nMouse of the Month<\/span><\/a>\n <\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n\n\n
\n Cre Transgenic Mouse Series_1<\/span>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
Cre recombinase is a 38 kDa enzyme derived from the bacteriophage P1 which specifically recognizes 34 bp loxP sites. Cre has been shown to effectively mediate the excision of DNA flanked by loxP sites. Cre-loxP system is a very useful tool for time-space-specific knock-out the genes which can not be investigated in adults because of their embryonic lethality in conventional gene-targetting.\n<\/div>\n

 <\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\"mn0606_0101\"
\nBRC No. 01153 Six3-Cre mouse<\/span><\/td>\n		Six3-Cre<\/b><\/span><\/td>\nPromoter<\/b><\/td>\n:<\/b><\/td>\nSine oculis-related homeobox 3<\/td>\n<\/tr>\n
Application<\/b><\/td>\n:<\/b><\/td>\nNeurobiology<\/td>\n<\/tr>\n
Expression<\/b><\/td>\n:<\/b><\/td>\ndeveloping retina and ventral forebrain<\/td>\n<\/tr>\n
Depositor<\/b><\/td>\n:<\/b><\/td>\nDr. Yasuhide Furuta
\n(Univ. of Texas)<\/td>\n<\/tr>\n
BRC No. 01153 TgN(Six3 Cre)22Frt<\/a><\/td>\n<\/tr>\n
BRC No. 01154 TgN(Six3 Cre)69Frt<\/a><\/td>\n<\/tr>\n
<\/td>\n<\/tr>\n
\"mn0606_0102\"
\nBRC No. 01297 DBH-Cre mouse<\/span><\/td>\n		DBH-Cre<\/b><\/span><\/td>\nPromoter<\/b><\/td>\n:<\/b><\/td>\nDopamin beta hydroxylase<\/td>\n<\/tr>\n
Application<\/b><\/td>\n:<\/b><\/td>\nNeurobiology<\/td>\n<\/tr>\n
Expression<\/b><\/td>\n:<\/b><\/td>\ntypical noradrenergic and adrenergic cell groups, transient catecholaminergic cell types<\/td>\n<\/tr>\n
Depositor<\/b><\/td>\n:<\/b><\/td>\nDr. Kazuto Kobayashi
\n(Fukushima Medical Univ.)<\/td>\n<\/tr>\n
BRC No. 01297 DBH-Cre\/6-8<\/a><\/td>\n<\/tr>\n
BRC No. 01492 DBH-Cre\/9-9<\/a><\/td>\n<\/tr>\n
<\/td>\n<\/tr>\n
\"mn0606_0103\"
\nBRC No. 01342 Emx1-Cre mouse<\/span><\/td>\n		Emx1-Cre<\/b><\/span><\/td>\nPromoter<\/b><\/td>\n:<\/b><\/td>\nEmpty spiracles homolog 1<\/td>\n<\/tr>\n
Application<\/b><\/td>\n:<\/b><\/td>\nNeurobiology<\/td>\n<\/tr>\n
Expression<\/b><\/td>\n:<\/b><\/td>\ndorsal telencephalon, neocortex, hippocampus, and olfactory bulb<\/td>\n<\/tr>\n
Depositor<\/b><\/td>\n:<\/b><\/td>\nDr. Shigeyoshi Itohara
\n(RIKEN BSI)<\/td>\n<\/tr>\n
BRC No. 00808 Emx1-Cre<\/a><\/td>\n<\/tr>\n
BRC No. 01342 Emx1-Cre Tg1<\/a><\/td>\n<\/tr>\n
BRC No. 01343 Emx1-Cre Tg2<\/a><\/td>\n<\/tr>\n
BRC No. 01344 Emx1-Cre Tg3<\/a><\/td>\n<\/tr>\n
BRC No. 01345 Emx1-Cre KI \u0394neo<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

June 2006 Mouse of the Month Cre Transgenic Mouse Series_1 Cre recombinase is a 38 kDa enzyme derived from the bacteriophage P1 which specifically recognizes 34 bp loxP sites. Cre has been shown to ef […]<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":198,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_seopress_robots_follow":"","_seopress_robots_imageindex":"","_seopress_robots_snippet":"","_seopress_robots_primary_cat":"","_seopress_robots_breadcrumbs":"","_seopress_robots_freeze_modified_date":"","_seopress_robots_custom_modified_date":"","_seopress_robots_canonical":"","_seopress_social_fb_title":"","_seopress_social_fb_desc":"","_seopress_social_fb_img":"","_seopress_social_fb_img_attachment_id":0,"_seopress_social_fb_img_width":0,"_seopress_social_fb_img_height":0,"_seopress_social_twitter_title":"","_seopress_social_twitter_desc":"","_seopress_social_twitter_img":"","_seopress_social_twitter_img_attachment_id":0,"_seopress_social_twitter_img_width":0,"_seopress_social_twitter_img_height":0,"_seopress_redirections_value":"","_seopress_redirections_enabled":"","_seopress_redirections_enabled_regex":"","_seopress_redirections_logged_status":"both","_seopress_redirections_param":"","_seopress_redirections_type":301,"_seopress_analysis_target_kw":"","footnotes":"","_wp_rev_ctl_limit":""},"class_list":["post-6665","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/6665","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/comments?post=6665"}],"version-history":[{"count":10,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/6665\/revisions"}],"predecessor-version":[{"id":19103,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/6665\/revisions\/19103"}],"up":[{"embeddable":true,"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/198"}],"wp:attachment":[{"href":"http:\/\/mus.brc.riken.jp\/ja\/wp-json\/wp\/v2\/media?parent=6665"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}