Strain Information | |
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Image | |
BRC No. | RBRC00805 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6;129S-Hoxc<tm1Nogu>/NoguRbrc |
Former Common name | Hox C cluster Knockout mice |
H-2 Haplotype | |
ES Cell line | |
Background strain | C57BL/6NJcl |
Appearance | black [a/a B/B C/C] |
Strain development | Developed by Dr. Hirofumi Suemori, Meiji Institute of Health Science in 1996. |
Strain description | B6;129S-Hoxc<tm1Nogu>. Hoxc gene deficient mice. Homozygous mutant mice are embryonic lethal. |
Colony maintenance | backcross to C57BL/6N (Heterozygote x C57BL/6NJcl) |
References | Dev Biol., 220, 333-342 (2000). 10753520 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP15loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter puropuromycin acyltransferase (Streptomyces alboniger)15puro |
Ordering Information | |
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Donor DNA | mouse homeo box C cluster genomic DNA, PEF1a (elongation factor 1a promoter), Phage P1 loxP, Streptomyces alboniger puromycin-resistance gene |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Del. Biol., 220, 333-342 (2000). |
Depositor | Hirofumi Suemori (Kanagawa Academy of Science and Technology) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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Schorderet P, Duboule D. Structural and functional differences in the long non-coding RNA hotair in mouse and human. PLoS Genet 7(5) e1002071(2011) 21637793 Tschopp P, Fraudeau N, Béna F, Duboule D. Reshuffling genomic landscapes to study the regulatory evolution of Hox gene clusters. Proc Natl Acad Sci U S A 108(26) 10632-7(2011) 21670281 |