Strain Information | |
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Image | |
BRC No. | RBRC11277 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6N-Pkn1<tm1.1(T778A)Hmuk> |
Former Common name | PKN1[T778A] |
H-2 Haplotype | |
ES Cell line | RENKA [C57BL/6NCrlCrlj] |
Background strain | |
Appearance | |
Strain development | established in 2007. back-crossed to Charles River C57BL/6N more than 10 times. homozygous mutant mice -- leukopenia, splenomegaly |
Strain description | kinase-negative mutant of PKN1 |
Colony maintenance | |
References | Sci. Rep., 7(1):7663 (2017). doi: 10.1038/s41598-017-07936-9. 28794483 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP8loxP |
Ordering Information | |
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Donor DNA | phage P1 loxP site, mouse Pkn1 genomic DNA |
Research application | Cre/loxP system |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Sci Rep. Aug 9;7(1):7663 (2017). doi: 10.1038/s41598-017-07936-9.Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using e-mail. |
Depositor | Hideyuki Mukai (Kobe University) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |