************************************************************************ RIKEN BioResource Research Center Mouse E-mail News No. 154 ************************************************************************ RIKEN BioResource Research Center (BRC) is pleased to update you with the latest information. ======= Contents ======================================================= - Today's model for human disease - User publications - Our publication - Newly deposited mouse strains ======================================================================== +----------------------------------------------------------------------- | Today's model for human disease +----------------------------------------------------------------------- Vitamin D receptor VDR KO mice RBRC05885 B6.Cg-Vdr<tm1Ska> A kind of GPCR GPRC5B KO mice RBRC10166 B6.Cg-Gprc5b<tm1Yhir> ACAM(CLMP) Tg mice controlled by adipocyte P2 promoter RBRC06443 C57BL/6-Tg(Fabp4-Clmp)4Jwada RBRC06444 C57BL/6-Tg(Fabp4-Clmp)11Jwada RBRC06445 C57BL/6-Tg(Fabp4-Clmp)22Jwada Phosphatidylcholine biosynthetic enzyme Pemt KO mice RBRC06436 C57BL/6-Pemt<tm1> Today's model for human disease https://mus.brc.riken.jp/en/todays_tool_and_model +----------------------------------------------------------------------- | User publications +----------------------------------------------------------------------- The following result has been newly reported by users. We are honored to introduce new publications to the science community. Therefore, we look forward to receiving your publications too. RBRC06344 C57BL/6-App<tm3(NL-G-F)Tcs> Biechele G, Franzmeier N, Blume T, Ewers M, Luque JM, Eckenweber F, Sacher C, Beyer L, Ruch-Rubinstein F, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Cumming P, Bartenstein P, Rominger A, Hoglinger GU, Herms J, Brendel M. Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases. J Neuroinflammation. 2020 Dec 14;17(1):374. doi: 10.1186/s12974-020-02046-2. https://doi.org/10.1186/s12974-020-02046-2 RBRC02759 B6.Cg-Atg7<tm1Tchi> Luo P, Yan H, Du J, Chen X, Shao J, Zhang Y, Xu Z, Jin Y, Lin N, Yang B, He Q. PLK1 (polo like kinase 1)-dependent autophagy facilitates gefitinib-induced hepatotoxicity by degrading COX6A1 (cytochrome c oxidase subunit 6A1). Autophagy. 2020 Dec 14;1-17. doi: 10.1080/15548627.2020.1851492. https://doi.org/10.1080/15548627.2020.1851492 RBRC01840 B6.Cg-Grin2d<tm1Mim>/MimRbrc Neupane C, Sharma R, Pai YH, Lee SY, Jeon BH, Kim HW, Stern JE, Park JB. High salt intake recruits tonic activation of NR2D subunit-containing extrasynaptic NMDARs in vasopressin neurons. J Neurosci. 2020 Dec 9;JN-RM-1742-20. doi: 10.1523/JNEUROSCI.1742-20.2020. https://doi.org/10.1523/JNEUROSCI.1742-20.2020 RBRC05843 B6.Cg-Actb<tm1(tetO-ChR2*E123T/T159C)Ahky> RBRC02317 B6.129-Pde10a2<tm1(tTA)Yok> Suzuki E, Momiyama T. M1 muscarinic acetylcholine receptor-mediated inhibition of GABA release from striatal medium spiny neurons onto cholinergic interneurons. Eur J Neurosci. 2020 Dec 3. doi: 10.1111/ejn.15074. https://doi.org/10.1111/ejn.15074 +----------------------------------------------------------------------- | Our publication +----------------------------------------------------------------------- A review article entitled "Substrains matter in phenotyping of C57BL/6 mice" is published online in collaboration with Okayama University of Science. +----------------------------------------------------------------------- | Newly deposited mouse strains +----------------------------------------------------------------------- Dr. Ryoichiro Kageyama, Kyoto University RBRC11188 STOCK Tg(Hes7-Achilles)1Kag Dr. Kenji Tanaka, Keio University RBRC11200 B6.Cg-BDNF<tm1(tetO)Kftnk> Dr. Hiroyuki Morita, Gifu University RBRC11204 C57BL/6-Adipoq<em1(tdTomato)Gifim> https://mus.brc.riken.jp/en/mailnews/kitaku_list/20201221_k __________________________________________________________________ *We hope you find the contents of this message of interest. However, if you would prefer to unsubscribe from future e-mails, please send an e-mail to animal.brc@riken.jp. *If you have any questions or comments, please send an e-mail to animal.brc@riken.jp. *Content is subject to change without notice. *All Rights Reserved. __________________________________________________________________ RIKEN BioResource Research Center Experimental Animal Division 3-1-1 Koyadai, Tsukuba-shi Ibaraki, 305-0074 Japan animal.brc@riken.jp https://mus.brc.riken.jp/en/ __________________________________________________________________ 2021.01.20.