RIKEN BioResource Research Center Mouse E-mail News No. 154

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RIKEN BioResource Research Center Mouse E-mail News No. 154
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RIKEN BioResource Research Center (BRC) is pleased to update you with the 
latest information.

======= Contents =======================================================
- Today's model for human disease
- User publications
- Our publication
- Newly deposited mouse strains
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| Today's model for human disease
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Vitamin D receptor VDR KO mice
RBRC05885 B6.Cg-Vdr<tm1Ska>

A kind of GPCR GPRC5B KO mice
RBRC10166 B6.Cg-Gprc5b<tm1Yhir>

ACAM(CLMP) Tg mice controlled by adipocyte P2 promoter 
RBRC06443 C57BL/6-Tg(Fabp4-Clmp)4Jwada
RBRC06444 C57BL/6-Tg(Fabp4-Clmp)11Jwada
RBRC06445 C57BL/6-Tg(Fabp4-Clmp)22Jwada

Phosphatidylcholine biosynthetic enzyme Pemt KO mice
RBRC06436 C57BL/6-Pemt<tm1>

Today's model for human disease
 https://mus.brc.riken.jp/en/todays_tool_and_model


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| User publications
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 The following result has been newly reported by users. We are
honored to introduce new publications to the science community.
Therefore, we look forward to receiving your publications too.

RBRC06344 C57BL/6-App<tm3(NL-G-F)Tcs>
Biechele G, Franzmeier N, Blume T, Ewers M, Luque JM, Eckenweber F, Sacher C, 
Beyer L, Ruch-Rubinstein F, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, 
Cumming P, Bartenstein P, Rominger A, Hoglinger GU, Herms J, Brendel M.
Glial activation is moderated by sex in response to amyloidosis but not to 
tau pathology in mouse models of neurodegenerative diseases.
J Neuroinflammation. 2020 Dec 14;17(1):374. doi: 10.1186/s12974-020-02046-2.
https://doi.org/10.1186/s12974-020-02046-2

RBRC02759 B6.Cg-Atg7<tm1Tchi>
Luo P, Yan H, Du J, Chen X, Shao J, Zhang Y, Xu Z, Jin Y, Lin N, Yang B, He Q.
PLK1 (polo like kinase 1)-dependent autophagy facilitates gefitinib-induced 
hepatotoxicity by degrading COX6A1 (cytochrome c oxidase subunit 6A1).
Autophagy. 2020 Dec 14;1-17. doi: 10.1080/15548627.2020.1851492.
https://doi.org/10.1080/15548627.2020.1851492

RBRC01840 B6.Cg-Grin2d<tm1Mim>/MimRbrc
Neupane C, Sharma R, Pai YH, Lee SY, Jeon BH, Kim HW, Stern JE, Park JB.
High salt intake recruits tonic activation of NR2D subunit-containing 
extrasynaptic NMDARs in vasopressin neurons.
J Neurosci. 2020 Dec 9;JN-RM-1742-20. doi: 10.1523/JNEUROSCI.1742-20.2020.
https://doi.org/10.1523/JNEUROSCI.1742-20.2020

RBRC05843 B6.Cg-Actb<tm1(tetO-ChR2*E123T/T159C)Ahky>
RBRC02317 B6.129-Pde10a2<tm1(tTA)Yok>
Suzuki E, Momiyama T.
M1 muscarinic acetylcholine receptor-mediated inhibition of GABA release 
from striatal medium spiny neurons onto cholinergic interneurons.
Eur J Neurosci. 2020 Dec 3. doi: 10.1111/ejn.15074.
https://doi.org/10.1111/ejn.15074

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| Our publication
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A review article entitled "Substrains matter in phenotyping of C57BL/6 mice" 
is published online in collaboration with Okayama University of Science.


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| Newly deposited mouse strains
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Dr. Ryoichiro Kageyama, Kyoto University
RBRC11188 STOCK Tg(Hes7-Achilles)1Kag

Dr. Kenji Tanaka, Keio University
RBRC11200 B6.Cg-BDNF<tm1(tetO)Kftnk>

Dr. Hiroyuki Morita, Gifu University
RBRC11204 C57BL/6-Adipoq<em1(tdTomato)Gifim>

https://mus.brc.riken.jp/en/mailnews/kitaku_list/20201221_k


__________________________________________________________________
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*Content is subject to change without notice.
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__________________________________________________________________
RIKEN BioResource Research Center
Experimental Animal Division
3-1-1 Koyadai, Tsukuba-shi
Ibaraki, 305-0074 Japan
animal@brc.riken.jp
https://mus.brc.riken.jp/en/
__________________________________________________________________
2021.01.20.


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