TOP > Mouse of the Month archive

Mouse of the Month archive

2026

Apr 2026
The Crhbp Gene involved in REM Sleep


2025

Apr 2025
Induction of chromoanasynthesis using Recql5 mutant mice


2024

Dec 2024
In vivo BioID mice for analyzing protein-protein interactions


Apr 2024
The relationship between CD103-positive DCs and oral tolerance


Mar 2024
Visualization of trans homophilic interactions in neurons using a novel probe


Jan 2024
A novel luminescent Tg strain expressing emerald luciferase


2023

Oct 2023
Transcriptional rhythm control of the clock gene Bmal1


Sep 2023
Oxytocin Receptor (Oxtr) functional analysis tools


Jul 2023
A fluorescent reporter strain for sexing at the preimplantation embryos

May 2023
Neuronal imaging in vivo with a novel calcium indicator G-CaMP9a

Feb 2023
Gal4/UAS expression system-dependent
gene recombination and cell imaging mice

Jan 2023
Cre driver mice for B cell lineage

2022

Nov 2022
RASopathies (RAS/MAPK syndromes) model mice

Oct 2022
Cre driver mice for germ cell lineage

Aug 2022
Oxytocin neuron Cre-driver mice

Jun 2022
A key gene in cancer research Meflin(Islr) functional analysis tools

Apr 2022
TRiCK (TRiple Coloured germ layer Knock-in) mouse

Mar 2022
A spatiotemporally controllable Cre-driver strain

Feb 2022
A novel protein knockdown technology: auxin-inducible degron (AID) 2 system

2021

Nov 2021
A model mouse strain for 22q11.2 deletion syndrome with a 3.0-Mb deletion

Oct 2021
A novel vanishing white matter disease model; toy mice

Sep 2021
Induction of hibernation-like state in mice

Aug 2021
Gata3 otic vesicle enhancer
for Gata3 inner ear-specific expression

May 2021
Cas9 Tg mice to realize efficient genome editing mouse production

Mar 2021
A novel Down syndrome mouse model by chromosome engineering technique

Feb 2021
Ucp1 in vivo imaging mice

2020

Dec 2020
Kaede mice for in vivo monitoring of cell migration

Nov 2020
A key transcription factor for innate immunity: IRF3

Mar 2020
Pyroptosis executor: gasdermin D (GSDMD)

Feb 2020
A novel hairless mouse strain for in vivo imaging

2019

Dec 2019
Glycinergic neuron Cre-driver mice

Nov 2019
A novel GLUT1DS model strain by ENU mutagenesis

Oct 2019
3xFLAG-dCas9 expressing mice for enChIP analysis

Aug 2019
PHF6: a conductor of HSC self-renewal

Jul 2019
Multifunctional transcriptional factor; Heat shock transcription factor 1 (HSF1)

Jun 2019
Haemophilia B model mice

Apr 2019
Unusual pain perception phenotype in Zfhx2-deficient mice

Mar 2019
Long-sleep mouse model induced by Sik3 splice mutation

Feb 2019
iRFP transgenic mice for in vivo imaging

Jan 2019
Bcl6 reporter mice for immune memory research

2018

Dec 2018
Bicistronic Insulin1-Cre knock-in mice

Nov 2018
Autism spectrum disorder (ASD) model mice

Oct 2018
Green-to-red fluorescent-convertible Cre-reporter mice

2017

Sep 2017
RAQP4, the main subset of the aquaporin water channel family in the brain

Aug 2017
Transcranial imaging of intracellular Ca2+ in astrocytes and neurons

Jun 2017
A tool for understanding endogenous sphingolipid synthesis

Apr 2017
Regulatory function of nuclear protein IκB-ζ in inflammatory responses

Mar 2017
Identifying pheromone circuits in mice

Feb 2017
Cell type-specific expression of photoconvertible fluorescent protein KikGR

2016

Oct 2016
Autophagy monitoring congenic strains

Oct 2016
Atg7 deletion in various tissues

Sep 2016
A new CreERT2 line for studying PDGFRα-expressing cells in vivo

Aug 2016
Monitoring cell replacement and migration in vivo with Kaede

Jun 2016
Essential role of condensins I and II for early embryonic divisions in mice

May 2016
Impaired female fertility in Tinagl1 deficient mice

Apr 2016
Impaired female fertility in Tinagl1 deficient mice

Mar 2016
A knock-in mouse strain with R124H human TGFBI mutationC

Feb 2016
Activation of NF-κB pathway and suppression of cell death through linear polyubiquitination activity of LUBAC

Jan 2016
Tracking and depletion of XCR1-positive dendritic cells

2015

Dec 2015
Estimating germline mutation rate in laboratory mouse

Nov 2015
A tool for olfactory sensory neuron-specific mosaic analysis

Oct 2015
A tool for olfactory sensory neuron-specific mosaic analysis

Sep 2015
One-step generation of multiple transgenic mouse lines

Aug 2015
Multiple roles of Tetraspanin-interacting protein IGSF8

Jul 2015
SIP1 expression patterns in the brain

Jun 2015
Genetic tool for controlled G-CaMP7 expression in vivo

May 2015
A key factor for epigenetic inheritance of DNA methylation

Apr 2015
Mouse model of human 15q11–13 duplication

Feb 2015
Sirt1 overexpression in neural and vascular endothelial cells

Jan 2015
Clarifying the role of Fbxw7 in cancer

2014

Dec 2014
CXCL12-abundant reticular cells as a microenvironmental niche in bone marrow

Nov 2014
C429S mutation in the mouse β-catenin gene leads to infertility

Oct 2014
A model mouse strain for Dravet syndrome

Sep 2014
App knock-in mouse strains: new models for Alzheimer’s disease

Aug 2014
Cell signaling of stress response via ASK1

Jul 2014
Visualizing the neuronal activity-regulated gene Arc

Jun 2014
Conditional ablation of HMGB1 in mice

May 2014
Acquired A20 (Tnfaip3) deficiency in mice

Apr 2014
Targeted disruption of exon 52 in the dystrophin gene

Mar 2014
Novel ROSA26 Cre-reporter knock-in C57BL/6N mice

Jan 2014
Fluorescent labeling of GABAergic neurons in the GAD67-GFP knock-in mouse

2013

Dec 2013
New reporter line for optogenetic stimulation at high frequencies

Nov 2013
Skin abnormalities in mice lacking CD109

Oct 2013
Lymphotoxin signaling in thymic organogenesis

Sep 2013
Altered barrier integrity and enhanced sensitization by filaggrin deficiency

Aug 2013
Visualizing primordial germ cell development in mice

Jul 2013
Cre-mediated recombination in villus epithelial cells of the intestine

Jun 2013
A tool for the conditional deletion of the transcriptional repressor Bcl6

May 2013
Regulating gene expression in photoreceptor precursor cells

Apr 2013
Expanding the repertoire of optogenetic control

Mar 2013
Cre reporter mouse expressing nuclear-localized beta-galactosidase

Feb 2013
Multifunctional Rosa26 reporter mouse strain

Jan 2013
Monitoring endoplasmic reticulum stress in mice

2012

Dec 2012
CD169+ macrophages in immune regulation

Nov 2012
Metabolic impact of glucagon deficiency

Oct 2012
A tool for the generation of germline-competent iPS cells

Sep 2012
Critical roles of TRAF6

Aug 2012
Lethal anemia and chronic polyarthritis caused by undigested mammalian DNA

Jul 2012
PD-1 deficiency and autoimmunity

Jun 2012
Atg7 deletion in various tissues

May 2012
Renin-angiotensin system in hypertension

Apr 2012
Nrf2 in stress response and cancer development

Mar 2012
Autophagy monitoring congenic strains

Feb 2012
Green congenic mouse strains

Jan 2012
A gene for central respiratory regulation

2011

Dec 2011
Neurodegeneration via endoplasmic reticulum stress

Nov 2011
Hairless Congenics for Dermatology Studies

Oct 2011
Visualizing Histone H2A Variants in Chromatin

Sep 2011
TRPM1, a causative molecule for night blindness in retinal ON bipolar cells

Aug 2011
GP2 on M Cells for the Mucosal Immune Response

Jul 2011
A Systemic Inflammation Model:Unc93B1 with a D34A mutation

Jun 2011
A Dnmt1 knock-out mouse for epigenetic studies

May 2011
Detecting Autophagy in the Heart

Apr 2011
A Conditional Lung Injury Model

Mar 2011
Visualizing neuronal activity

2010

Jul 2010
A model for retinitis pigmentosa (RP)

Jun 2010
A model for psychiatric disorder


2009
Oct 2009
Dopamine receptor knockout mice
 Sep 2009
Sox2: An essential factor for maintaining neural stem cell
 Aug 2009
Visualizing the Wnt signal pathway
 Jul 2009
Atg5: An essential molecule of autophagy
Jun 2009
C57BL/6-Ly5 Antigen (Ptprc) Congenic Strains
 May 2009
The only one strain for study of NF-kB/RelA subunit in vivo
 Apr 2009
A Japanese wild-derived inbred strain for functional genomics
 Mar 2009
Fucci mice for visualizing cell-cycle in vivo
Feb 2009
The Tsix/Xist-deficient Strains
 Jan 2009
BALB/c Hbb Congenic Strains

2008
Aug 2008
Delphilin KO Mouse		 Jul 2008
Lck-p19Arf Transgenic Mouse		 Jun 2008
Drs KO Mouse		 May 2008
TH-GFP Transgenic Mouse
Apr 2008
PRAT4A KO Mouse		 Mar 2008
Disc1 Mutant Mouse		 Feb 2008
T-bet Transgenic Mouse		 Jan 2008
mDomino KO Mouse

2007
Dec 2007
Nanog-GFP Transgenic Mouse
 Nov 2007
EGFP-Akt Transgenic Mouse
 Oct 2007
Dmp1-HBEGF Transgenic Mouse

 Sep 2007
Gdf5Rgsc451 Mouse
Aug 2007
K14-AhR-CA transgenic mice
 Jul 2007
p38α floxed mouse
 Jun 2007
Card15/Nod2 KO mouse
 May 2007
Lefty & Noda
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Apr 2007
Kf-1 Knock-out Mouse
 Mar 2007
ERAI transgenic mouse
 Feb 2007
FLPe transgenic mouse
 Jan 2007
RECS1 knockout mouse

2006
Dec 2006
Mitfmi-bw mutant mouse
 Nov 2006
MFG-E8 KO mouse
 Oct 2006
p27 KO mouse
 Sep 2006
Thy1-SpH transgenic mouse
Aug 2006
Semaphorin III/D gene targeting mice
 Jul 2006
Cre Transgenic Mouse Series_2
 Jun 2006
Cre Transgenic Mouse Series_1

 May 2006
A model for bipolar disorder
Apr 2006
Heparin-binding EGF-like growth factor (HB-EGF)-deficient mouse
 Jan 2006
A Model for Hyperlipidemia SHL: Spontaneous Mutation in the Apolipoprotein E gene

2005
Dec 2005
A Model for Type 2 Hyper-IgM Syndrome
 Nov 2005
SMXA-RI Strains 		Oct 2005
Nrf2 & Keap1
 Sep 2005
Visualization of Primordial Germ Cells in Vivo
Jun 2005
Analysis of Rho/Rho-kinase singnaling pathway
 Jun 2005
A Model for Tumor Biology: p53 KO mouse
 May 2005
A Model for Impaired Cytokine Secretion
 Apr 2005
A Model for Congenital Alopecia


 

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