Sentinel mouse program
The RIKEN BRC has adopted the sentinel mouse program, a specialized approach with the microisolator cage system. A sentinel mouse cage containing five mice is laid on a microisolator cage rack and small pieces of bedding material from all cages of the rack are collected and placed in the sentinel mouse cage. Two mice from a sentinel cage are subjected to examination quarterly; one is for in-house examination and the other is sent to the ICLAS monitoring center of the Central Institute for Laboratory Animals, Kawasaki, Japan. The health report you receive is a copy of the then-most-recent Health Report guaranteed by a veterinarian at the ICLAS Monitoring Center.
We classify the microorganisms into four classes according to the risk presented to the mouse in Japan. All sentinel mice are tested for class A and B. Sentinel mice kept in the room for immuno-deficient mice are screened for class C as well. Class D contains certain pathogens believed not to exist in the Japanese mouse colony; therefore, mice are examined only at the request and expense of the recipient.
Announcement on monitoring of Hantaan virus and dermatophytes
Health Report 
(BRC facility Health Report in the last year and a half)
Health Reports in RIKEN BRC Cryorecovery Work
Bimonthly Sentinel Health Report
Date 2F 3F 4F
3-A to 3-D 3-1 to 3-8 4-A to 4-C
January, 2021 
4-C :
December, 2020 4-A,B :
November, 2020 3-A,B :
3-C,D :
October, 2020
September, 2020
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December, 2011
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October, 2011
