************************************************************************ RIKEN BioResource Research Center Mouse E-mail News No. 166 ************************************************************************ RIKEN BioResource Research Center (BRC) is pleased to update you with the latest information. ======= Contents ======================================================= - Today's model for human disease - User publications - Newly deposited mouse strains ======================================================================== +----------------------------------------------------------------------- | Today's model for human disease +----------------------------------------------------------------------- Cloned mice lines derived from antigen-specific CD4+ T cells RBRC10902 C.CD2-Tcra-V10<Df> Tcrb-V5<Df>/Ogu RBRC10903 C.CD2-Tcra-V10<Dp1> Tcrb-V31<Dp1>/Ogu Ca2+-dependent modulator Cys proteases Capn6 gene KO mice RBRC06237 B6.Cg-Capn6<tm1Hiso> RBRC06238 ICR.Cg-Capn6<tm1Hiso> Axon guidance molecule Sema4d gene KO mice RBRC10202 CB17.Cg-Sema4D<tm1In> Sema4D receptor Plxnb1 gene KO mice RBRC10201 CB17.Cg-Plxnb1<tm1Matl> Today's model for human disease https://mus.brc.riken.jp/en/todays_tool_and_model +----------------------------------------------------------------------- | User publications +----------------------------------------------------------------------- The following result has been newly reported by users. We are honored to introduce new publications to the science community. Therefore, we look forward to receiving your publications too. RBRC00897 B6.Cg-Aicda<tm1Hon> (N10)/HonRbrc Luo Y, Zhang X, Chen R, Li R, Liu Y, Zhang J, Liu Q, Si M, Liu J, Wu B, Wang X, Wu S, Zhang Y, Zhang X, Guo D, He X, Pan T, Zhang H. USP10 regulates B cell response to SARS-CoV-2 or HIV-1 nanoparticle vaccines through deubiquitinating AID. Signal Transduct Target Ther. 2022 Jan 4;7(1):7. doi: 10.1038/s41392-021-00858-z. https://doi.org/10.1038/s41392-021-00858-z RBRC00806 GFP-LC3#53 Andrea K. H. Stavoe, Erika L. F. Holzbaur. Live Imaging of Autophagosome Biogenesis and Maturation in Primary Neurons. Neuromethods. 2022 Jan 1;23-40. doi: 10.1007/978-1-0716-1589-8_3. https://doi.org/10.1007/978-1-0716-1589-8_3 RBRC01390 B6.129P2-Nfe2l2<tm1Mym>/MymRbrc Fotini Filippopoulou, George I. Habeos, Vagelis Rinotas, Antonia Sophocleous, Gerasimos P. Sykiotis, Eleni Douni, Dionysios V. Chartoumpekis. Dexamethasone Administration in Mice Leads to Less Body Weight Gain over Time, Lower Serum Glucose, and Higher Insulin Levels Independently of NRF2. Antioxidants. 2021 Dec 21 ;11(1):4. doi: 10.3390/antiox11010004. https://doi.org/10.3390/antiox11010004 RBRC00639 JF1/Msf Matsuzaki H, Miyajima Y, Fukamizu A, Tanimoto K. Orientation of mouse H19 ICR affects imprinted H19 gene expression through promoter methylation-dependent and -independent mechanisms. Commun Biol. 2021 Dec 17;4(1):1410. doi: 10.1038/s42003-021-02939-9. https://doi.org/10.1038/s42003-021-02939-9 RBRC02706 B6.Cg-Tg(FucciS/G2/M)#504Bsi RBRC02707 B6.Cg-Tg(FucciG1)#596Bsi Zotos D, Quast I, Li-Wai-Suen CSN, McKenzie CI, Robinson MJ, Kan A, Smyth GK, Hodgkin PD, Tarlinton DM. The concerted change in the distribution of cell cycle phases and zone composition in germinal centers is regulated by IL-21. Nat Commun. 2021 Dec 9;12(1):7160. doi: 10.1038/s41467-021-27477-0. https://doi.org/10.1038/s41467-021-27477-0 RBRC02332 B6.Cg-Tg(Drd2-YFP)364-5 RBRC03111 C57BL/6J-Tg(mDrd1-YFP)680-1Koba Faruk MO, Tsuboi D, Yamahashi Y, Funahashi Y, Lin YH, Ahammad RU, Hossen E, Amano M, Nishioka T, Tzingounis AV, Yamada K, Nagai T, Kaibuchi K. Muscarinic signaling regulates voltage-gated potassium channel KCNQ2 phosphorylation in the nucleus accumbens via protein kinase C for aversive learning. J Neurochem. 2021 Dec 8. doi: 10.1111/jnc.15555. https://doi.org/10.1111/jnc.15555 RBRC01253 B6;129S4-Gopc<tm1.1Tno>/Rbrc Bizkarguenaga M, Gomez-Santos L, Madrid JF, Sáez FJ, Alonso E. Zona Pellucida sperm-binding protein 3 receptor distribution during Gopc-/- globozoospermic spermatogenesis. Microsc Res Tech. 2021 Dec 6. doi: 10.1002/jemt.24009. https://doi.org/10.1002/jemt.24009 RBRC02290 STOCK Tg(Nanog-GFP,Puro)1Yam Evgeniia Borisova, Ken Nishimura, Yuri An, Miho Takami, Jingyue Li, Dan Song, Mami Matsuo-Takasaki, Dorian Luijkx, Shiho Aizawa, Akihiro Kuno, Eiji Sugihara, Taka-aki Sato, Fumiaki Yumoto, Tohru Terada, Koji Hisatake, Yohei Hayashi. Structurally-discovered KLF4 variants accelerate and stabilize reprogramming to pluripotency. iScience. 2021 Dec 14;103525. doi: 10.1016/j.isci.2021.103525. https://doi.org/10.1016/j.isci.2021.103525 RBRC06344 C57BL/6-App<tm3(NL-G-F)Tcs> Liu X, Zhou Q, Zhang JH, Wang KY, Saito T, Saido TC, Wang X, Gao X, Azuma K. Microglia-Based Sex-Biased Neuropathology in Early-Stage Alzheimer's Disease Model Mice and the Potential Pharmacologic Efficacy of Dioscin. Cells. 2021 Nov 22;10(11):3261. doi: 10.3390/cells10113261. https://doi.org/10.3390/cells10113261 RBRC01151 B6;129S7-Hey1<tm1Kkb>/YsaRbrc RBRC02707 B6.Cg-Tg(FucciG1)#596Bsi Harada Y, Yamada M, Imayoshi I, Kageyama R, Suzuki Y, Kuniya T, Furutachi S, Kawaguchi D, Gotoh Y. Cell cycle arrest determines adult neural stem cell ontogeny by an embryonic Notch-nonoscillatory Hey1 module. Nat Commun. 2021 Nov 12;12(1):6562. doi: 10.1038/s41467-021-26605-0. https://doi.org/10.1038/s41467-021-26605-0 RBRC04895 B6(Cg)-Timd4<tm1Osa> Lee SA, Kim D, Min C, Moon B, Lee J, Moon H, Yang S, Lee CS, Lee G, Park D. Phagocyte Chemoattraction Is Induced through the Mcp-1-Ccr2 Axis during Efferocytosis. Cells. 2021 Nov 10;10(11):3115. doi: 10.3390/cells10113115. https://doi.org/10.3390/cells10113115 +----------------------------------------------------------------------- | Newly deposited mouse strains +----------------------------------------------------------------------- Dr. Tadashi Okamura, Research Institute National Center for Global Health and Medicine RBRC11565 C.Cg-Ace2<em1(ACE2)Okt> Dr. Yoshitaka Fujihara, National Cerebral and Cardiovascular Center RBRC11576 B6D2-Smim8<em1Ncvc> RBRC11577 B6D2-Smim9<em1Ncvc> Dr. Yoko Aoki, Tohoku University RBRC11578 C.Cg-Hras<tm1.1(G12S)Tumg> https://mus.brc.riken.jp/en/mailnews/kitaku_list/20211220_k __________________________________________________________________ *We hope you find the contents of this message of interest. However, if you would prefer to unsubscribe from future e-mails, please send an e-mail to animal.brc@riken.jp. *If you have any questions or comments, please send an e-mail to animal.brc@riken.jp. *Content is subject to change without notice. *All Rights Reserved. __________________________________________________________________ RIKEN BioResource Research Center Experimental Animal Division 3-1-1 Koyadai, Tsukuba-shi Ibaraki, 305-0074 Japan animal.brc@riken.jp https://mus.brc.riken.jp/en/ __________________________________________________________________ 2022.01.26.
