************************************************************************ RIKEN BioResource Research Center Mouse E-mail News No. 168 ************************************************************************ RIKEN BioResource Research Center (BRC) is pleased to update you with the latest information. ======= Contents ======================================================= - Delays in resource shipments to Europe - Special topic: Mouse of the Month "A spatiotemporally controllable Cre-driver strain" - Today's model for human disease - User publications - Newly deposited mouse strains ======================================================================== +----------------------------------------------------------------------- | Delays in resource shipments to Europe +----------------------------------------------------------------------- Due to the current war in Ukraine, shipments of mouse resources to Europe are under disruption and deliveries of the resources may experience more delays than usual. Thank you for your understanding and cooperation. We are continuing to pray for the swift restoration of peace in Ukraine. +----------------------------------------------------------------------- | Special topic: Mouse of the Month +----------------------------------------------------------------------- A spatiotemporally controllable Cre-driver strain RBRC11090 C57BL6/J-Actb<em1(tetO-PA-cre)ttaka> Depositors: Takeshi Takarada, Ph.D., Tomoka Takao, Ph.D. Okayama University https://mus.brc.riken.jp/en/mouse_of_month/mar_2022_mm Mouse of the Month archive https://mus.brc.riken.jp/en/mouse_of_month +----------------------------------------------------------------------- | Today's model for human disease +----------------------------------------------------------------------- Infantile-onset leukoencephalopathy model mice RBRC10267 B6;129-Mlc1<tm1kftnk> (Mlc1-STOPtetO KI) RBRC10268 B6;129-Mlc1<tm1.1kftnk> (Mlc1-tetO KI) Early infantile epileptic encephalopathy model mice RBRC03654 B6;129-Arx<tm(GCG)Kki>/7-1Rbrc Lissencephaly model mice RBRC03438 B6;129P2-Arx<tm1Kki>/6Rbrc RBRC03435 B6;129P2-Arx<tm1Kki>/1Rbrc Protrudin (Zfyve27) KO mice RBRC10084 B6.Cg-Zfyve27<tm1Kei> Today's model for human disease https://mus.brc.riken.jp/en/todays_tool_and_model +----------------------------------------------------------------------- | User publications +----------------------------------------------------------------------- The following result has been newly reported by users. We are honored to introduce new publications to the science community. Therefore, we look forward to receiving your publications too. https://rrc.nbrp.jp/references/register RBRC01390 B6.129P2-Nfe2l2<tm1Mym>/MymRbrc Kim A, Koo JH, Lee JM, Joo MS, Kim TH, Kim H, Jun DW, Kim SG. NRF2-mediated SIRT3 induction protects hepatocytes from ER stress-induced liver injury. FASEB J.2022 Mar;36(3):e22170. doi: 10.1096/fj.202101470R https://doi.org/10.1096/fj.202101470R RBRC06344 C57BL/6-App<tm3(NL-G-F)Tcs> MG6(RCB2403) Xie Z, Meng J, Kong W, Wu Z, Lan F, Narengaowa, Hayashi Y, Yang Q, Bai Z, Nakanishi H, Qing H, Ni J. Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer's disease. Aging Cell. 2022 Feb 19;e13565. doi: 10.1111/acel.13565. https://doi.org/10.1111/acel.13565 RBRC00007 Nagel F, Schaefer AK, Gonçalves IF, Acar E, Oszwald A, Kaiser P, Kain R, Trescher K, Eilenberg WH, Brostjan C, Santer D, Kiss A, Podesser BK. The expression and role of tenascin C in abdominal aortic aneurysm formation and progression. Interact Cardiovasc Thorac Surg. 2022 Feb 8;ivac018. doi: 10.1093/icvts/ivac018. https://doi.org/10.1093/icvts/ivac018 RBRC04395 B6;129-Siglec1<tm1(HBEGF)Mtka> Chalot M, Barroca V, Devanand S, Hoffschir F, Roméo PH, Moreno SG. Deleterious effect of bone marrow-resident macrophages on hematopoietic stem cells in response to total body irradiation. Blood Adv. 2022 Jan 31;bloodadvances.2021005983. doi: 10.1182/bloodadvances.2021005983. https://doi.org/10.1182/bloodadvances.2021005983 RBRC03654 B6;129-Arx<tm(GCG)Kki>/7-1Rbrc Drongitis D, Caterino M, Verrillo L, Santonicola P, Costanzo M, Poeta L, Attianese B, Barra A, Terrone G, Lioi MB, Paladino S, Di Schiavi E, Costa V, Ruoppolo M, Miano MG. Deregulation of microtubule organization and RNA metabolism in Arx models for Lissencephaly and developmental epileptic encephalopathy. Hum Mol Genet. 2022 Jan 31;ddac028. doi: 10.1093/hmg/ddac028. https://doi.org/10.1093/hmg/ddac028 +----------------------------------------------------------------------- | Newly deposited mouse strains +----------------------------------------------------------------------- Dr. Haruhiko Bito, The University of Tokyo RBRC11575 C57BL/6N-Gt(ROSA)26Sor<tm1(CAG-G-CaMP9a,-R-CaMP2)Hbto> Dr. Takahisa Furukawa, Osaka University RBRC11590 C57BL/6-Cyfip2<tm1c(EUCOMM)Wtsi>/Tfur RBRC11591 B6-Peli3<em1Tfur> Dr. Toru Nakano, Osaka University RBRC11596 B6;129Ola-Ddc<em1(hKO1)Nkn> Dr. Kazuto Kobayashi, Fukushima Medical University RBRC11597 C57BL/6J-Tg(Th-GFP-IR84a/IR8a)2-1Koba Dr. Junichi Fujii, Yamagata University RBRC11601 C57BL/6J-Cndp2<em1Jufu> RBRC11603 C57BL/6J-Prdx4<em1Jufu> Dr. Atsushi Hoshino, Kyoto Prefectural University of Medicine RBRC11605 B6.Cg-Keap1<em1Iha>/Ahosh https://mus.brc.riken.jp/en/mailnews/kitaku_list/20220218_k __________________________________________________________________ *We hope you find the contents of this message of interest. However, if you would prefer to unsubscribe from future e-mails, please send an e-mail to animal.brc@riken.jp. *If you have any questions or comments, please send an e-mail to animal.brc@riken.jp. *Content is subject to change without notice. *All Rights Reserved. __________________________________________________________________ RIKEN BioResource Research Center Experimental Animal Division 3-1-1 Koyadai, Tsukuba-shi Ibaraki, 305-0074 Japan animal.brc@riken.jp https://mus.brc.riken.jp/en/ __________________________________________________________________ 2022.03.16.