RIKEN BioResource Research Center Mouse E-mail News No. 168

RIKEN BioResource Research Center Mouse E-mail News No. 168

RIKEN BioResource Research Center (BRC) is pleased to update you with the 
latest information.

======= Contents =======================================================
- Delays in resource shipments to Europe
- Special topic: Mouse of the Month
  "A spatiotemporally controllable Cre-driver strain"
- Today's model for human disease
- User publications
- Newly deposited mouse strains

| Delays in resource shipments to Europe

 Due to the current war in Ukraine, shipments of mouse resources to Europe 
are under disruption and deliveries of the resources may experience more 
delays than usual.
Thank you for your understanding and cooperation.
We are continuing to pray for the swift restoration of peace in Ukraine.

| Special topic: Mouse of the Month

A spatiotemporally controllable Cre-driver strain
  RBRC11090 C57BL6/J-Actb<em1(tetO-PA-cre)ttaka>
Depositors: Takeshi Takarada, Ph.D., Tomoka Takao, Ph.D.
           Okayama University 


Mouse of the Month archive

| Today's model for human disease

Infantile-onset leukoencephalopathy model mice
RBRC10267 B6;129-Mlc1<tm1kftnk> (Mlc1-STOPtetO KI)
RBRC10268 B6;129-Mlc1<tm1.1kftnk> (Mlc1-tetO KI)

Early infantile epileptic encephalopathy model mice
RBRC03654 B6;129-Arx<tm(GCG)Kki>/7-1Rbrc

Lissencephaly model mice
RBRC03438 B6;129P2-Arx<tm1Kki>/6Rbrc
RBRC03435 B6;129P2-Arx<tm1Kki>/1Rbrc

Protrudin (Zfyve27) KO mice
RBRC10084 B6.Cg-Zfyve27<tm1Kei>

Today's model for human disease

| User publications

 The following result has been newly reported by users. We are
honored to introduce new publications to the science community.
Therefore, we look forward to receiving your publications too.

RBRC01390 B6.129P2-Nfe2l2<tm1Mym>/MymRbrc
Kim A, Koo JH, Lee JM, Joo MS, Kim TH, Kim H, Jun DW, Kim SG.
NRF2-mediated SIRT3 induction protects hepatocytes from 
ER stress-induced liver injury.
FASEB J.2022 Mar;36(3):e22170. doi: 10.1096/fj.202101470R

RBRC06344 C57BL/6-App<tm3(NL-G-F)Tcs>
Xie Z, Meng J, Kong W, Wu Z, Lan F, Narengaowa, Hayashi Y, 
Yang Q, Bai Z, Nakanishi H, Qing H, Ni J.
Microglial cathepsin E plays a role in neuroinflammation 
and amyloid β production in Alzheimer's disease.
Aging Cell. 2022 Feb 19;e13565. doi: 10.1111/acel.13565.

Nagel F, Schaefer AK, Gonçalves IF, Acar E, Oszwald A, Kaiser P, Kain R, 
Trescher K, Eilenberg WH, Brostjan C, Santer D, Kiss A, Podesser BK.
The expression and role of tenascin C in abdominal aortic aneurysm 
formation and progression.
Interact Cardiovasc Thorac Surg. 2022 Feb 8;ivac018. doi: 10.1093/icvts/ivac018.

RBRC04395 B6;129-Siglec1<tm1(HBEGF)Mtka>
Chalot M, Barroca V, Devanand S, Hoffschir F, Roméo PH, Moreno SG.
Deleterious effect of bone marrow-resident macrophages on 
hematopoietic stem cells in response to total body irradiation.
Blood Adv. 2022 Jan 31;bloodadvances.2021005983. doi: 10.1182/bloodadvances.2021005983.

RBRC03654 B6;129-Arx<tm(GCG)Kki>/7-1Rbrc
Drongitis D, Caterino M, Verrillo L, Santonicola P, Costanzo M, 
Poeta L, Attianese B, Barra A, Terrone G, Lioi MB, Paladino S, 
Di Schiavi E, Costa V, Ruoppolo M, Miano MG.
Deregulation of microtubule organization and RNA metabolism in 
Arx models for Lissencephaly and developmental epileptic encephalopathy.
Hum Mol Genet. 2022 Jan 31;ddac028. doi: 10.1093/hmg/ddac028.

| Newly deposited mouse strains

Dr. Haruhiko Bito, The University of Tokyo
RBRC11575 C57BL/6N-Gt(ROSA)26Sor<tm1(CAG-G-CaMP9a,-R-CaMP2)Hbto>

Dr. Takahisa Furukawa, Osaka University
RBRC11590 C57BL/6-Cyfip2<tm1c(EUCOMM)Wtsi>/Tfur
RBRC11591 B6-Peli3<em1Tfur>

Dr. Toru Nakano, Osaka University
RBRC11596 B6;129Ola-Ddc<em1(hKO1)Nkn>

Dr. Kazuto Kobayashi, Fukushima Medical University
RBRC11597 C57BL/6J-Tg(Th-GFP-IR84a/IR8a)2-1Koba

Dr. Junichi Fujii, Yamagata University
RBRC11601 C57BL/6J-Cndp2<em1Jufu>
RBRC11603 C57BL/6J-Prdx4<em1Jufu>

Dr. Atsushi Hoshino, Kyoto Prefectural University of Medicine
RBRC11605 B6.Cg-Keap1<em1Iha>/Ahosh


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