************************************************************************ RIKEN BioResource Research Center Mouse E-mail News No. 174 ************************************************************************ RIKEN BioResource Research Center (BRC) is pleased to update you with the latest information. ======= Contents ======================================================= - NBRP Mouse & Rat News - Today's model for human disease - User publications - Newly deposited mouse strains ======================================================================== +----------------------------------------------------------------------- | NBRP Mouse & Rat News +----------------------------------------------------------------------- In recent years, with development of gene engineering technologies, there has been a rapid increase in development and collection of useful resources, which are common or associated with mice and rats. Therefore, NBRP-Mouse and NBRP-Rat have collaborated to launch "NBRP Mouse & Rat News" to introduce related resources on the latest topics. We hope this will help you in your search for resources. Functional analysis tools for GAD isoforms Mouse resources RBRC11364 B6-Gad1<tm1(tetO)Ksak> RBRC11365 B6;Cg-Gad1<tm1.1(tTA2)Kftnk> Rat resources NBRP rat No.:0906 LE-Gad1<em15Yyan> NBRP rat No.:0907 LE-Gad2<em24Yyan> Depositor:Yuchio Yanagawa, M.D., Ph.D, Gunma University https://mus.brc.riken.jp/en/mouse_and_rat/sep_2022_mr NBRP Mouse & Rat News archive https://mus.brc.riken.jp/en/mouse_and_rat +----------------------------------------------------------------------- | Today's model for human disease +----------------------------------------------------------------------- Skin melanoma model mice RBRC00694 B6.Cg-Tg(KRT14-Kitl)1Takk/TakkRbrc Atopic dermatitis model mice RBRC06233 DS/Shi-Trpv3<Nh>/Shi RBRC06234 B6.DS-Trpv3<Nh>/Shi RBRC06235 C.DS-Trpv3<Nh>/Shi IL4 KO mice RBRC04920 B6;129S2-Il4<tm1Kopf> RBRC04921 C;129S2-Il4<tm1Kopf> RBRC05130 D1;129S2-Il4<tm1Kopf> https://mus.brc.riken.jp/en/todays_tool_and_model +----------------------------------------------------------------------- | User publications +----------------------------------------------------------------------- The following result has been newly reported by users. We are honored to introduce new publications to the science community. Therefore, we look forward to receiving your publications too. https://rrc.nbrp.jp/references/register RBRC09798 B6.Cg-Ano5<tm1.2Naga> Li X, Wang L, Wang H, Qin A, Qin X. Ano5 modulates calcium signaling during bone homeostasis in gnathodiaphyseal dysplasia. NPJ Genom Med. 2022 Aug 18;7(1):48. doi: 10.1038/s41525-022-00312-1. https://doi.org/10.1038/s41525-022-00312-1 RBRC02142 B6.129S2-Pdcd1<tm1Hon>/HonRbrc Gao Y, Song B, Aoki S, Ito K. Conjugation of human serum albumin and flucloxacillin provokes specific immune response in HLA-B<*>57:01 transgenic mice. Immunol Lett. 2022 Aug 10;6705. doi: 10.1016/j.imlet.2022.08.002. https://doi.org/10.1016/j.imlet.2022.08.002 RBRC01361 B6.Cg-Trp53<tm1Sia>/Rbrc Kanatsu-Shinohara M, Naoki H, Tanaka T, Tatehana M, Kikkawa T, Osumi N, Shinohara T. Regulation of male germline transmission patterns by the Trp53-Cdkn1a pathway. Stem Cell Reports. 2022 Aug 1;S2213-6711(22)00366-6. doi: 10.1016/j.stemcr.2022.07.007. https://doi.org/10.1016/j.stemcr.2022.07.007 RBRC04841 B6N.129P2-Bhlhe40<tm1Homy> Hirata H, Kamohara A, Murayama M, Nishioka K, Honda H, Urano Y, Soejima H, Oki S, Kukita T, Kawano S, Mawatari M, Kukita A. A novel role of helix-loop-helix transcriptional factor Bhlhe40 in osteoclast activation. J Cell Physiol. 2022 Jul 31. doi: 10.1002/jcp.30844. https://doi.org/10.1002/jcp.30844 RBRC02192 B6.129-Mapk14<tm1.2Otsu> Luo Q, Schnöder L, Hao W, Litzenburger K, Decker Y, Tomic I, Menger MD, Liu Y, Fassbender K. p38α-MAPK-deficient myeloid cells ameliorate symptoms and pathology of APP-transgenic Alzheimer's disease mice. Aging Cell. 2022 Aug;21(8):e13679. doi: 10.1111/acel.13679. https://doi.org/10.1111/acel.13679 RBRC06344 C57BL/6-App<tm3(NL-G-F)Tcs> Qiao Y, Gast G, Su X, Saito T, Saido TC, Holmes TC, Xu X. Hippocampal neural circuit connectivity alterations in an Alzheimer's disease mouse model revealed by monosynaptic rabies virus tracing. Neurobiol Dis. 2022 Jul 14;172:105820. doi: 10.1016/j.nbd.2022.105820. https://doi.org/10.1016/j.nbd.2022.105820 RBRC00398 B6.129P2-Mmp2<tm1Ito>/ItoRbrc Bormann T, Maus R, Stolper J, Tort Tarrés M, Brandenberger C, Wedekind D, Jonigk D, Welte T, Gauldie J, Kolb M, Maus UA. Role of matrix metalloprotease-2 and MMP-9 in experimental lung fibrosis in mice. Respir Res. 2022 Jul 8;23(1):180. doi: 10.1186/s12931-022-02105-7. https://doi.org/10.1186/s12931-022-02105-7 +----------------------------------------------------------------------- | Newly deposited mouse strains +----------------------------------------------------------------------- Dr. Hiroshi Hamada, RIKEN BDR RBRC11733 B6-Tg(Nodal NDE-5HT6/GCaMP6,5HT6/mCherry)35Hmd RBRC11734 B6-Tg(Nodal NDE-5HT6/GCaMP6,RGECO1)130AHmd RBRC11735 B6-Tg(Nodal NDE-5HT6/Pvalb,lacZ)21AHmd RBRC11736 B6-Tg(Cfap53,lacZ)23Hmd RBRC11737 B6-Cfap53<em1Hmd> RBRC11738 B6-Cfap53<em2Hmd> RBRC11739 B6-Tg(Cfap53/Venus)66Hmd RBRC11740 B6;129-Dnah11<tm1(Venus)Hmd> RBRC11741 B6-Dnah9<em1Hmd> RBRC11742 B6-Ttc25<em1Hmd> RBRC11743 B6;129-Dnah9<tm1(Venus)Hmd> RBRC11744 B6-Bicc1<em1Hmd> RBRC11745 B6C3-Tg(Foxj1-cre)1Hmd RBRC11746 STOCK Tg(Foxj1-cre/ERT2)1Hmd RBRC11747 STOCK Tg(Cluap1/Venus)24Hmd RBRC11748 B6-Cluap1<em1Hmd> RBRC11749 B6-Cluap1<em2Hmd> RBRC11750 B6-Cfap45<em1Hmd> RBRC11751 B6;129-Tg(NDE-hsp-Lefty2,lacZ)14Hmd RBRC11752 B6;129-Tg(NDE-hsp-Nodal,lacZ)36Hmd RBRC11777 STOCK Tg(Sfrp1-cre/ERT2)1Hmd RBRC11778 B6-Tg((NDE)4-hsp-dsVenus-Dand5_3'UTR)5Hmd RBRC11779 B6-Dand5<em1Hmd> RBRC11780 B6-Dand5<em2Hmd> RBRC11781 STOCK Wnt5b<tm1Hmd> RBRC11782 B6-Tppp3<em1Hmd> RBRC11783 STOCK Tg(Pitx2c-Pitx2 ASE-Pitx2c,lacZ)39Hmd RBRC11784 STOCK Tg(Pitx2c-Pitx2 ASE-Pitx2c,lacZ)55Hmd RBRC11785 STOCK Dchs1<em2Hmd> Dr. Atsu Aiba, The University of Tokyo RBRC11786 B6.129-Sema3f<tm1Atai> https://mus.brc.riken.jp/en/mailnews/kitaku_list/20220819_k __________________________________________________________________ *We hope you find the contents of this message of interest. However, if you would prefer to unsubscribe from future e-mails, please send an e-mail to animal.brc@riken.jp. *If you have any questions or comments, please send an e-mail to animal.brc@riken.jp. *Content is subject to change without notice. *All Rights Reserved. __________________________________________________________________ RIKEN BioResource Research Center Experimental Animal Division 3-1-1 Koyadai, Tsukuba-shi Ibaraki, 305-0074 Japan animal.brc@riken.jp https://mus.brc.riken.jp/en/ __________________________________________________________________ 2022.09.13.