RIKEN BioResource Research Center Mouse E-mail News No. 174

RIKEN BioResource Research Center Mouse E-mail News No. 174

RIKEN BioResource Research Center (BRC) is pleased to update you with the 
latest information.

======= Contents =======================================================
- NBRP Mouse & Rat News
- Today's model for human disease
- User publications
- Newly deposited mouse strains

| NBRP Mouse & Rat News

In recent years, with development of gene engineering technologies, 
there has been  a rapid increase in development and collection of 
useful resources, which are common or associated with mice and rats. 
Therefore, NBRP-Mouse and NBRP-Rat have collaborated to launch 
"NBRP Mouse & Rat News" to introduce related resources on the latest topics. 
We hope this will help you in your search for resources.

Functional analysis tools for GAD isoforms
Mouse resources
 RBRC11364 B6-Gad1<tm1(tetO)Ksak>
 RBRC11365 B6;Cg-Gad1<tm1.1(tTA2)Kftnk>
Rat resources
 NBRP rat No.:0906 LE-Gad1<em15Yyan>
 NBRP rat No.:0907 LE-Gad2<em24Yyan>

Depositor:Yuchio Yanagawa, M.D., Ph.D,
           Gunma University


NBRP Mouse & Rat News archive

| Today's model for human disease

Skin melanoma model mice
RBRC00694 B6.Cg-Tg(KRT14-Kitl)1Takk/TakkRbrc

Atopic dermatitis model mice
RBRC06233 DS/Shi-Trpv3<Nh>/Shi
RBRC06234 B6.DS-Trpv3<Nh>/Shi
RBRC06235 C.DS-Trpv3<Nh>/Shi

IL4 KO mice
RBRC04920 B6;129S2-Il4<tm1Kopf>
RBRC04921 C;129S2-Il4<tm1Kopf>
RBRC05130 D1;129S2-Il4<tm1Kopf>


| User publications

 The following result has been newly reported by users. We are
honored to introduce new publications to the science community.
Therefore, we look forward to receiving your publications too.

RBRC09798 B6.Cg-Ano5<tm1.2Naga>
Li X, Wang L, Wang H, Qin A, Qin X.
Ano5 modulates calcium signaling during bone homeostasis in gnathodiaphyseal dysplasia.
NPJ Genom Med. 2022 Aug 18;7(1):48. doi: 10.1038/s41525-022-00312-1.

RBRC02142 B6.129S2-Pdcd1<tm1Hon>/HonRbrc
Gao Y, Song B, Aoki S, Ito K.
Conjugation of human serum albumin and flucloxacillin provokes specific immune 
response in HLA-B<*>57:01 transgenic mice.
Immunol Lett. 2022 Aug 10;6705. doi: 10.1016/j.imlet.2022.08.002.

RBRC01361 B6.Cg-Trp53<tm1Sia>/Rbrc
Kanatsu-Shinohara M, Naoki H, Tanaka T, Tatehana M, Kikkawa T, Osumi N, Shinohara T.
Regulation of male germline transmission patterns by the Trp53-Cdkn1a pathway.
Stem Cell Reports. 2022 Aug 1;S2213-6711(22)00366-6. doi: 10.1016/j.stemcr.2022.07.007. 

RBRC04841 B6N.129P2-Bhlhe40<tm1Homy>
Hirata H, Kamohara A, Murayama M, Nishioka K, Honda H, Urano Y, Soejima H, 
Oki S, Kukita T, Kawano S, Mawatari M, Kukita A.
A novel role of helix-loop-helix transcriptional factor Bhlhe40 in osteoclast activation.
J Cell Physiol. 2022 Jul 31. doi: 10.1002/jcp.30844. 

RBRC02192 B6.129-Mapk14<tm1.2Otsu>
Luo Q, Schnöder L, Hao W, Litzenburger K, Decker Y, Tomic I, Menger MD, 
Liu Y, Fassbender K.
p38α-MAPK-deficient myeloid cells ameliorate symptoms and pathology of 
APP-transgenic Alzheimer's disease mice.
Aging Cell. 2022 Aug;21(8):e13679. doi: 10.1111/acel.13679.

RBRC06344 C57BL/6-App<tm3(NL-G-F)Tcs>
Qiao Y, Gast G, Su X, Saito T, Saido TC, Holmes TC, Xu X.
Hippocampal neural circuit connectivity alterations in an Alzheimer's disease 
mouse model revealed by monosynaptic rabies virus tracing.
Neurobiol Dis. 2022 Jul 14;172:105820. doi: 10.1016/j.nbd.2022.105820.

RBRC00398 B6.129P2-Mmp2<tm1Ito>/ItoRbrc
Bormann T, Maus R, Stolper J, Tort Tarrés M, Brandenberger C, Wedekind D, 
Jonigk D, Welte T, Gauldie J, Kolb M, Maus UA.
Role of matrix metalloprotease-2 and MMP-9 in experimental lung fibrosis in mice.
Respir Res. 2022 Jul 8;23(1):180. doi: 10.1186/s12931-022-02105-7. 

| Newly deposited mouse strains

Dr. Hiroshi Hamada, RIKEN BDR
RBRC11733 B6-Tg(Nodal NDE-5HT6/GCaMP6,5HT6/mCherry)35Hmd
RBRC11734 B6-Tg(Nodal NDE-5HT6/GCaMP6,RGECO1)130AHmd
RBRC11735 B6-Tg(Nodal NDE-5HT6/Pvalb,lacZ)21AHmd
RBRC11736 B6-Tg(Cfap53,lacZ)23Hmd
RBRC11737 B6-Cfap53<em1Hmd>
RBRC11738 B6-Cfap53<em2Hmd>
RBRC11739 B6-Tg(Cfap53/Venus)66Hmd
RBRC11740 B6;129-Dnah11<tm1(Venus)Hmd>
RBRC11741 B6-Dnah9<em1Hmd>
RBRC11742 B6-Ttc25<em1Hmd>
RBRC11743 B6;129-Dnah9<tm1(Venus)Hmd>
RBRC11744 B6-Bicc1<em1Hmd>
RBRC11745 B6C3-Tg(Foxj1-cre)1Hmd
RBRC11746 STOCK Tg(Foxj1-cre/ERT2)1Hmd
RBRC11747 STOCK Tg(Cluap1/Venus)24Hmd
RBRC11748 B6-Cluap1<em1Hmd>
RBRC11749 B6-Cluap1<em2Hmd>
RBRC11750 B6-Cfap45<em1Hmd>
RBRC11751 B6;129-Tg(NDE-hsp-Lefty2,lacZ)14Hmd
RBRC11752 B6;129-Tg(NDE-hsp-Nodal,lacZ)36Hmd
RBRC11777 STOCK Tg(Sfrp1-cre/ERT2)1Hmd
RBRC11778 B6-Tg((NDE)4-hsp-dsVenus-Dand5_3'UTR)5Hmd
RBRC11779 B6-Dand5<em1Hmd>
RBRC11780 B6-Dand5<em2Hmd>
RBRC11781 STOCK Wnt5b<tm1Hmd>
RBRC11782 B6-Tppp3<em1Hmd>
RBRC11783 STOCK Tg(Pitx2c-Pitx2 ASE-Pitx2c,lacZ)39Hmd
RBRC11784 STOCK Tg(Pitx2c-Pitx2 ASE-Pitx2c,lacZ)55Hmd
RBRC11785 STOCK Dchs1<em2Hmd>

Dr. Atsu Aiba, The University of Tokyo
RBRC11786 B6.129-Sema3f<tm1Atai>


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RIKEN BioResource Research Center
Experimental Animal Division
3-1-1 Koyadai, Tsukuba-shi
Ibaraki, 305-0074 Japan

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