BRC Mouse E-mail News No. 179

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BRC Mouse E-mail News No. 179
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RIKEN BioResource Research Center (BRC) is pleased to update you with the 
latest information.

======= Contents =======================================================
- IMGC2023
- The 70th Annual Meeting of the Japanese Association for Laboratory Animal Science
- Mouse of the Month 
  "Gal4/UAS expression system-dependent gene recombination and cell imaging mice"
- Today's tool for functional analysis
- User publications
- Newly deposited mouse strains
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| IMGC2023 
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The IMGC2023 will be held at Tsukuba International Congress center in a 
hybrid format from March 28th through 31st, 2023.

 https://www.imgc36.org


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| The 70th Annual Meeting of the Japanese Association for Laboratory Animal Science 
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The 70th Annual Meeting of the Japanese Association for Laboratory Animal Science 
will be held at Tsukuba International Congress center from May 24th through 26th, 2023.

 https://cfmeeting.com/jalas70/en/index.html


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| Mouse of the Month
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Gal4/UAS expression system-dependent gene recombination and cell imaging mice
 RBRC11716 Crl:CD1(ICR)-Tg(UAS-cre/T2A/miRFP670)216Staka

Depositor: Satoru Takahashi, M.D., Ph.D. & Masaharu Yoshihara, M.D., Ph.D.
           University of Tsukuba

 https://mus.brc.riken.jp/en/mouse_of_month/feb_2023_mm

Mouse of the Month archive
 https://mus.brc.riken.jp/en/mouse_of_month


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| Today's tool for functional analysis
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Notch signaling fluorescent reporter mice
RBRC06137 ICR.Cg-Tg(TP1-venus)/YsaRbrc

A transcriptional co-activator in the Notch signaling Maml1 KO mice
RBRC10002 B6.Cg-Maml1<tm1Mkit>

Notch2 floxed mice
RBRC09647 B6;Cg-Notch2<tm1.1Hhi>

 https://mus.brc.riken.jp/en/todays_tool_and_model


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| User publications
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 The following result has been newly reported by users. We are
honored to introduce new publications to the science community.
Therefore, we look forward to receiving your publications too.
https://rrc.nbrp.jp/references/register

RBRC06342 C57BL/6-App<tm1(NL)Tcs>
Wang J, Chen P, Hu B, Cai F, Xu Q, Pan S, Wu Y, Song W.
Distinct effects of SDC3 and FGFRL1 on selective neurodegeneration in AD and PD.
FASEB J2023 Feb;37(2):e22773. doi: 10.1096/fj.202201359R.
https://doi.org/10.1096/fj.202201359R

RBRC04364 B6.Cg-Aqp4<tm1.1(GFP)Mysi>/5Rbrc
Nicosia M, Lee J, Beavers A, Kish D, Farr Gw, McGuirk PR, Pelletier MF, 
Lathia JD, Fairchild RL, Valujskikh A.
Water channel Aquaporin 4 is required for T cell receptor mediated 
lymphocyte activation.
Journal of Leukocyte Biology. doi: 10.1093/jleuko/qiad010.
https://doi.org/10.1093/jleuko/qiad010

RBRC01492 B6.Cg-Tg(DBH-cre)9-9Koba/KobaRbrc
Higashikuni Y, Liu W, Numata G, Tanaka K, Fukuda D, Tanaka Y, Hirata Y, 
Imamura T, Takimoto E, Komuro I, Sata M.
NLRP3 Inflammasome Activation Through Heart-Brain Interaction Initiates 
Cardiac Inflammation and Hypertrophy During Pressure Overload.
Circulation. 2023 Jan 24;147(4):338-355. doi: 10.1161/CIRCULATIONAHA.122.060860.
https://doi.org/10.1161/CIRCULATIONAHA.122.060860

RBRC01235 STOCK Ptpro<tm1Shs>/Rbrc
Shintani T, Suzuki R, Takeuchi Y, Shirasawa T, Noda M.
Deletion or inhibition of PTPRO prevents ectopic fat accumulation and 
induces healthy obesity with markedly reduced systemic inflammation.
Life Sci. 2023 Jan 15;313:121292. doi: 10.1016/j.lfs.2022.121292.
https://doi.org/10.1016/j.lfs.2022.121292

RBRC06402 B6;129P2-Cdkn1c<tm2.1Kei>
Lozano-Ureña A, Lázaro-Carot L, Jiménez-Villalba E, 
Montalbán-Loro R, Mateos-White I, Duart-Abadía P, Martínez-Gurrea I, 
Nakayama KI, Fariñas I, Kirstein M, Gil-Sanz C, Ferrón SR.
IGF2 interacts with the imprinted gene Cdkn1c to promote terminal differentiation of 
neural stem cells.
Development. 2023 Jan 1;150(1):dev200563. doi: 10.1242/dev.200563.
https://doi.org/10.1242/dev.200563

RBRC03743 B6D2-Tg(CAG/Su9-DsRed2,Acr3-EGFP)RBGS002Osb
Wang Z, Wei H, Wu Z, Zhang X, Sun Y, Gao L, Zhang W, Su YQ, Zhang M.
The oocyte cumulus complex regulates mouse sperm migration in the oviduct.
Commun Biol. 2022 Dec 3;5(1):1327. doi: 10.1038/s42003-022-04287-8. 
https://doi.org/10.1038/s42003-022-04287-8


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| Newly deposited mouse strains
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Dr. Koichi Ikuta, Kyoto University
RBRC11886 B6.Cg-Il15<tm1.1Iku>
RBRC11887 B6.Cg-Il15<tm2Iku>

 https://mus.brc.riken.jp/en/mailnews/kitaku_list/20230120_k


__________________________________________________________________
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__________________________________________________________________
RIKEN BioResource Research Center
Experimental Animal Division
3-1-1 Koyadai, Tsukuba-shi
Ibaraki, 305-0074 Japan
animal.brc@riken.jp
https://mus.brc.riken.jp/en/
__________________________________________________________________
2023.02.16.


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