BRC Mouse E-mail News No. 180

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BRC Mouse E-mail News No. 180
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RIKEN BioResource Research Center (BRC) is pleased to update you with the 
latest information.

======= Contents =======================================================
- IMGC2023
- The 70th Annual Meeting of the Japanese Association for Laboratory Animal Science
- Today's model for human disease
- User publications
- Newly deposited mouse strains
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| IMGC2023 
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The IMGC2023 will be held at Tsukuba International Congress Center in a 
hybrid format from March 28th through 31st, 2023.
It is our great pleasure to invite you to visit our RIKEN BRC booth No.8 
during the conference.

 https://www.imgc36.org


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| The 70th Annual Meeting of the Japanese Association for Laboratory Animal Science 
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The 70th Annual Meeting of the Japanese Association for Laboratory Animal Science 
will be held at Tsukuba International Congress center from May 24th through 26th, 2023.

 https://cfmeeting.com/jalas70/en/index.html


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| Today's model for human disease
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Nasu-Hakola disease responsible gene Tyrobp(DAP12) KO mice
RBRC11704 B6.129P2-Tyrobp<tm1Ttk>

NGLY1 deficiency responsible gene Ngly1 KO mice
RBRC11332 JF1/Ms-Ngly1<em1Ta>

Fgf9 spontaneous mutant mice
RBRC09906 B6;B6D2-Fgf9<Eks>

Vimentin phosphorylated Site amino acid substitution mice
RBRC11719 B6.129S-Vim<tm1Sibg>

 https://mus.brc.riken.jp/en/todays_tool_and_model


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| User publications
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 The following result has been newly reported by users. We are
honored to introduce new publications to the science community.
Therefore, we look forward to receiving your publications too.
https://rrc.nbrp.jp/references/register

RBRC06344 C57BL/6-App<tm3(NL-G-F)Tcs>
RBRC03390 B6;129-Apoe<tm>/3SfuRbrc
RBRC03418 B6;129-Apoe<tm(APOE4)Sfu>/SfuRbrc
Honda K, Saito Y, Saito H, Toyoda M, Abe R, Saito T, Saido TC, Michikawa M, 
Taru H, Sobu Y, Hata S, Nakaya T, Suzuki T.
Accumulation of amyloid-β in the brain of mouse models of Alzheimer's disease 
is modified by altered gene expression in the presence of human apoE isoforms during aging.
Neurobiol Aging. 2023 Mar;123:63-74. doi: 10.1016/j.neurobiolaging.2022.12.003. 
https://doi.org/10.1016/j.neurobiolaging.2022.12.003

RBRC01347 B6.Cg-Tg(CAG-floxed neo-DT)03Osb
Matsuyama K, Takai S, Shigemura N, Nakatomi M, Kawamoto T, Kataoka S, Toyono T, Seta Y.
Ascl1-expressing cell differentiation in initially developed taste buds and taste organoids.
Cell Tissue Res. 2023 Feb 13. doi: 10.1007/s00441-023-03756-8. 
https://doi.org/10.1007/s00441-023-03756-8

RBRC05508 B6;129S4-Dnajc10<tm1Tiw>
Jeong H, Hong EH, Ahn JH, Cho J, Jeong JH, Kim CW, Yoon BI, Koo JH, Park YY, 
Yang YM, Iwawaki T, Vallance BA, Chang SY, Ko HJ.
ERdj5 protects goblet cells from endoplasmic reticulum stress-mediated apoptosis 
under inflammatory conditions.
Exp Mol Med. 2023 Feb 9. doi: 10.1038/s12276-023-00945-x. 
https://doi.org/10.1038/s12276-023-00945-x

RBRC04841 B6N.129P2-Bhlhe40<tm1Homy>
Wu Y, Wang H, Huo Y, Yan B, Honda H, Liu W, Yang J.
DIFFERENTIATED EMBRYONIC CHONDROCYTE EXPRESSED GENE-1 IS A CENTRAL SIGNALING COMPONENT 
IN THE DEVELOPMENT OF COLLAGEN-INDUCED RHEUMATOID ARTHRITIS.
J Biol Chem. 2023 Feb 3;102982. doi: 10.1016/j.jbc.2023.102982.
https://doi.org/10.1016/j.jbc.2023.102982

RBRC01346 C57BL/6-Prkdc<scid>/Rbrc
Ishino T, Kawashima S, Tanji E, Ueno T, Ueda Y, Ogasawara S, Sato K, Mano H, 
Ishihara S, Kato N, Kawazu M, Togashi Y.
Somatic mutations can induce a noninflamed tumour microenvironment via their 
original gene functions, despite deriving neoantigens.
Br J Cancer. 2023 Feb 2. doi: 10.1038/s41416-023-02165-6.
https://doi.org/10.1038/s41416-023-02165-6


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| Newly deposited mouse strains
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Dr. Kimiko Shimizu, Tokyo Medical and Dental University
RBRC11844 B6.Cg-Tg(TRE-Scop/Phlpp1)1Shimk

Dr. Takeshi Sakurai, University of Tsukuba
RBRC11845 B6.Cg-Tg(HCRT-EGFP)E2Stak

Dr. Hiroyuki Yaginuma, Fukushima Medical University
RBRC11903 C57BL/6J-Foxp1<em1Kmuk>
RBRC11904 C57BL/6J-Foxp1<em2Kmuk>
RBRC11905 C57BL/6J-Foxp1<em3Kmuk>

Dr. Shusaku Uchida, Kyoto University
RBRC11907 B6-Tg(Camk2a-Kdm5c/HA)#Kshu

Dr. Tomohiko Murakami, Osaka University
RBRC11909 C57BL/6J-Plxnb2<em1Tomu>
RBRC11910 D1;B6-Sema4d<em1Tomu>

 https://mus.brc.riken.jp/en/mailnews/kitaku_list/20230220_k


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__________________________________________________________________
RIKEN BioResource Research Center
Experimental Animal Division
3-1-1 Koyadai, Tsukuba-shi
Ibaraki, 305-0074 Japan
animal.brc@riken.jp
https://mus.brc.riken.jp/en/
__________________________________________________________________
2023.03.16.


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