************************************************************************ BRC Mouse E-mail News No. 186 ************************************************************************ RIKEN BioResource Research Center (BRC) is pleased to update you with the latest information. ======= Contents ======================================================= - Mouse of the Month "Transcriptional rhythm control of the clock gene Bmal1" - Today's tool for functional analysis - Our office will be closed on Monday, October 23rd - User publications - Our publication - Newly deposited mouse strains ======================================================================== +----------------------------------------------------------------------- | Mouse of the Month +----------------------------------------------------------------------- Transcriptional rhythm control of the clock gene Bmal1 C57BL/6J-Arntl<em1Yshtn> (RBRC11753) C57BL/6J-Arntl<em2Yshtn> (RBRC11754) Depositor: Hikari Yoshitane, Ph.D. (Tokyo Metropolitan Institute of Medical Science) https://mus.brc.riken.jp/en/mouse_of_month/oct_2023_mm Mouse of the Month archive https://mus.brc.riken.jp/en/mouse_of_month +----------------------------------------------------------------------- | Today's tool for functional analysis +----------------------------------------------------------------------- The clock gene Bmal1(Arntl) floxed mice RBRC11399 B6.Cg-Arntl<tm1Shbi> The clock gene Bmal1(Arntl) luminescent reporter mice RBRC09717 C57BL/6J-Tg(Arntl-cat,-luc*SLG)1Shige The clock gene Per1 luminescent reporter mice RBRC09608 C57BL/6-Tg(Per1-luc)Chron The clock genes Bmal1(Arntl) and Per1 luminescent reporter mice RBRC02670 C57BL/6J-Tg(Per1-VLUC,Bmal1-FLUC)CZ205-4Obs https://mus.brc.riken.jp/en/todays_tool_and_model +----------------------------------------------------------------------- | Our office will be closed on Monday, October 23rd +----------------------------------------------------------------------- Our office will be closed for the establishment anniversary on Monday, October 23rd. Thank you for your understanding. +----------------------------------------------------------------------- | User publications +----------------------------------------------------------------------- The following result has been newly reported by users. We are honored to introduce new publications to the science community. Therefore, we look forward to receiving your publications too. https://rrc.nbrp.jp/references/register RBRC01926 B6;129S4-Vamp7<tm1Aha> Xu H, Oses-Prieto JA, Khvotchev M, Jain S, Liang J, Burlingame A, Edwards RH. Adaptor protein AP-3 produces synaptic vesicles that release at high frequency by recruiting phospholipid flippase ATP8A1. Nat Neurosci. 2023 Sep 18. doi: 10.1038/s41593-023-01434-0. https://doi.org/10.1038/s41593-023-01434-0 RBRC06334 Morrice N, Vainio S, Mikkola K, van Aalten L, Gallagher JR, Ashford MLJ, McNeilly AD, McCrimmon RJ, Grosfeld A, Serradas P, Koffert J, Pearson ER, Nuutila P, Sutherland C. Metformin increases the uptake of glucose into the gut from the circulation in high-fat diet-fed male mice, which is enhanced by a reduction in whole-body Slc2a2 expression. Mol Metab. 2023 Sep 16;101807. doi: 10.1016/j.molmet.2023.101807. https://doi.org/10.1016/j.molmet.2023.101807 RBRC01195 B6.129S6-Grin2a<tm1Nak>/NakRbrc Su T, Lu Y, Fu C, Geng Y, Chen Y. GluN2A mediates ketamine-induced rapid antidepressant-like responses. Nat Neurosci. 2023 Sep 14. doi: 10.1038/s41593-023-01436-y. https://doi.org/10.1038/s41593-023-01436-y RBRC06410 B6.Cg-Nfkbiz<tm1.1Muta> Taylor TC, Coleman BM, Arunkumar SP, Dey I, Dillon JT, Ponde NO, Poholek AC, Schwartz DM, McGeachy MJ, Conti HR, Gaffen SL. IκBζ is an essential mediator of immunity to oropharyngeal candidiasis. Cell Host Microbe. 2023 Sep 11;S1931-3128(23)00341-4. doi: 10.1016/j.chom.2023.08.016. https://doi.org/10.1016/j.chom.2023.08.016 RBRC09921 C57BL/6N-Trp53<em1Rbrc> Enomoto Y, Katsura H, Fujimura T, Ogata A, Baba S, Yamaoka A, Kihara M, Abe T, Nishimura O, Kadota M, Hazama D, Tanaka Y, Maniwa Y, Nagano T, Morimoto M. Autocrine TGF-β-positive feedback in profibrotic AT2-lineage cells plays a crucial role in non-inflammatory lung fibrogenesis. Nat Commun. 2023 Aug 31;14(1):4956. doi: 10.1038/s41467-023-40617-y. https://doi.org/10.1038/s41467-023-40617-y +----------------------------------------------------------------------- | Our publication +----------------------------------------------------------------------- Nakashiba T, Ogoh K, Iwano S, Sugiyama T, Mizuno-Iijima S, Nakashima K, Mizuno S, Sugiyama F, Yoshiki A, Miyawaki A, Abe K. Development of two mouse strains conditionally expressing bright luciferases with distinct emission spectra as new tools for in vivo imaging. Lab Animal. doi: 10.1038/s41684-023-01238-6. https://doi.org/10.1038/s41684-023-01238-6 +----------------------------------------------------------------------- | Newly deposited mouse strains +----------------------------------------------------------------------- Dr. Hiroki Kokubo, Hiroshima University RBRC12023 B6-Sfrp5<tm1.1(cre)Kkb> RBRC12024 B6-Sfrp5<em1.1(ERT2/cre)Kkb> RBRC12025 B6-Sfrp5<em2.1(dre)Kkb> Dr. Kazushi Aoto, Hamamatsu University School of Medicine RBRC12079 STOCK Foxc2<tm1.1(cre/ERT2)Aot> Dr. Koichi Ojima, National Agriculture and Food Research Organization RBRC12081 B6-Myh7<em1Smur> RBRC12082 B6-Myh1<em1Tnsh> Dr. Junya Ito, Azabu University RBRC12083 C57BL/6J-Slc30a3<em1Itj> Dr. Tsukasa Ohmori, Jichi Medical University RBRC12089 C57BL/6-F9<tm1.1(hF9_R338L)Tsuka> Dr. Ichiro Taniuchi, RIKEN IMS RBRC12103 B6N;129(Cg)-Gt(ROSA)26Sor<tm2.1(CAG-scFV-AirID)Tani> https://mus.brc.riken.jp/en/mailnews/kitaku_list/20230920_k __________________________________________________________________ *We hope you find the contents of this message of interest. However, if you would prefer to unsubscribe from future e-mails, please send an e-mail to animal.brc@riken.jp. *If you have any questions or comments, please send an e-mail to animal.brc@riken.jp. *Content is subject to change without notice. *All Rights Reserved. __________________________________________________________________ RIKEN BioResource Research Center Experimental Animal Division 3-1-1 Koyadai, Tsukuba-shi Ibaraki, 305-0074 Japan animal.brc@riken.jp https://mus.brc.riken.jp/en/ __________________________________________________________________ 2023.10.13.