BRC Moue E-mail News No. 186

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BRC Mouse E-mail News No. 186
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RIKEN BioResource Research Center (BRC) is pleased to update you with the 
latest information.

======= Contents =======================================================
- Mouse of the Month "Transcriptional rhythm control of the clock gene Bmal1"
- Today's tool for functional analysis
- Our office will be closed on Monday, October 23rd
- User publications
- Our publication
- Newly deposited mouse strains
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| Mouse of the Month
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Transcriptional rhythm control of the clock gene Bmal1
 C57BL/6J-Arntl<em1Yshtn> (RBRC11753)
 C57BL/6J-Arntl<em2Yshtn> (RBRC11754)

Depositor: Hikari Yoshitane, Ph.D.
          (Tokyo Metropolitan Institute of Medical Science)

 https://mus.brc.riken.jp/en/mouse_of_month/oct_2023_mm

Mouse of the Month archive
 https://mus.brc.riken.jp/en/mouse_of_month


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| Today's tool for functional analysis
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The clock gene Bmal1(Arntl) floxed mice
RBRC11399 B6.Cg-Arntl<tm1Shbi>

The clock gene Bmal1(Arntl) luminescent reporter mice
RBRC09717 C57BL/6J-Tg(Arntl-cat,-luc*SLG)1Shige

The clock gene Per1 luminescent reporter mice
RBRC09608 C57BL/6-Tg(Per1-luc)Chron

The clock genes Bmal1(Arntl) and Per1 luminescent reporter mice
RBRC02670 C57BL/6J-Tg(Per1-VLUC,Bmal1-FLUC)CZ205-4Obs

 https://mus.brc.riken.jp/en/todays_tool_and_model


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| Our office will be closed on Monday, October 23rd
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 Our office will be closed for the establishment anniversary on Monday, October 23rd.
Thank you for your understanding.


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| User publications
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 The following result has been newly reported by users. We are
honored to introduce new publications to the science community.
Therefore, we look forward to receiving your publications too.
https://rrc.nbrp.jp/references/register

RBRC01926 B6;129S4-Vamp7<tm1Aha>
Xu H, Oses-Prieto JA, Khvotchev M, Jain S, Liang J, Burlingame A, Edwards RH.
Adaptor protein AP-3 produces synaptic vesicles that release at high frequency by recruiting phospholipid flippase ATP8A1.
Nat Neurosci. 2023 Sep 18. doi: 10.1038/s41593-023-01434-0. 
https://doi.org/10.1038/s41593-023-01434-0

RBRC06334
Morrice N, Vainio S, Mikkola K, van Aalten L, Gallagher JR, Ashford MLJ, McNeilly AD, McCrimmon RJ, Grosfeld A, Serradas P, Koffert J, Pearson ER, Nuutila P, Sutherland C.
Metformin increases the uptake of glucose into the gut from the circulation in high-fat diet-fed male mice, which is enhanced by a reduction in whole-body Slc2a2 expression.
Mol Metab. 2023 Sep 16;101807. doi: 10.1016/j.molmet.2023.101807. 
https://doi.org/10.1016/j.molmet.2023.101807

RBRC01195 B6.129S6-Grin2a<tm1Nak>/NakRbrc
Su T, Lu Y, Fu C, Geng Y, Chen Y.
GluN2A mediates ketamine-induced rapid antidepressant-like responses.
Nat Neurosci. 2023 Sep 14. doi: 10.1038/s41593-023-01436-y.
https://doi.org/10.1038/s41593-023-01436-y

RBRC06410 B6.Cg-Nfkbiz<tm1.1Muta>
Taylor TC, Coleman BM, Arunkumar SP, Dey I, Dillon JT, Ponde NO, Poholek AC, Schwartz DM, McGeachy MJ, Conti HR, Gaffen SL.
IκBζ is an essential mediator of immunity to oropharyngeal candidiasis.
Cell Host Microbe. 2023 Sep 11;S1931-3128(23)00341-4. doi: 10.1016/j.chom.2023.08.016.
https://doi.org/10.1016/j.chom.2023.08.016

RBRC09921 C57BL/6N-Trp53<em1Rbrc>
Enomoto Y, Katsura H, Fujimura T, Ogata A, Baba S, Yamaoka A, Kihara M, Abe T, Nishimura O, Kadota M, Hazama D, Tanaka Y, Maniwa Y, Nagano T, Morimoto M.
Autocrine TGF-β-positive feedback in profibrotic AT2-lineage cells plays a crucial role in non-inflammatory lung fibrogenesis.
Nat Commun. 2023 Aug 31;14(1):4956. doi: 10.1038/s41467-023-40617-y.
https://doi.org/10.1038/s41467-023-40617-y


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| Our publication
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Nakashiba T, Ogoh K, Iwano S, Sugiyama T, Mizuno-Iijima S, Nakashima K,  Mizuno S, Sugiyama F, Yoshiki A, Miyawaki A, Abe K.
Development of two mouse strains conditionally expressing bright luciferases with distinct emission spectra as new tools for in vivo imaging.
Lab Animal. doi: 10.1038/s41684-023-01238-6.
https://doi.org/10.1038/s41684-023-01238-6


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| Newly deposited mouse strains
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Dr. Hiroki Kokubo, Hiroshima University
RBRC12023 B6-Sfrp5<tm1.1(cre)Kkb>
RBRC12024 B6-Sfrp5<em1.1(ERT2/cre)Kkb>
RBRC12025 B6-Sfrp5<em2.1(dre)Kkb>

Dr. Kazushi Aoto, Hamamatsu University School of Medicine
RBRC12079 STOCK Foxc2<tm1.1(cre/ERT2)Aot>

Dr. Koichi Ojima, National Agriculture and Food Research Organization
RBRC12081 B6-Myh7<em1Smur>
RBRC12082 B6-Myh1<em1Tnsh>

Dr. Junya Ito, Azabu University
RBRC12083 C57BL/6J-Slc30a3<em1Itj>

Dr. Tsukasa Ohmori, Jichi Medical University
RBRC12089 C57BL/6-F9<tm1.1(hF9_R338L)Tsuka>

Dr. Ichiro Taniuchi, RIKEN IMS
RBRC12103 B6N;129(Cg)-Gt(ROSA)26Sor<tm2.1(CAG-scFV-AirID)Tani>

https://mus.brc.riken.jp/en/mailnews/kitaku_list/20230920_k


__________________________________________________________________
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*Content is subject to change without notice.
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__________________________________________________________________
RIKEN BioResource Research Center
Experimental Animal Division
3-1-1 Koyadai, Tsukuba-shi
Ibaraki, 305-0074 Japan
animal.brc@riken.jp
https://mus.brc.riken.jp/en/
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2023.10.13.


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