************************************************************************ BRC Mouse E-mail News No. 189 ************************************************************************ Thank you very much for your ongoing support of our activities and for following our webpage and email news. We are gradually shifting from email to web updates for delivering the latest news, available on our webpage and the official BRC X at https://x.com/RIKEN_BRC_en Your kind understanding is appreciated as we make this transition. Stay tuned for the latest from RIKEN BRC Experimental Animal Division. ======= Contents ======================================================= - Mouse of the Month "Visualization of trans homophilic interactions in neurons using a novel probe" - BRC Current Technology "Fertilization using spermatocytes overcomes azoospermia caused by meiotic arrest" "Establishment of nuclear transferred ES cells from wild-derived mouse leukocytes" - Today's model for human disease - User publications - Newly deposited mouse strains ======================================================================== +----------------------------------------------------------------------- | Mouse of the Month +----------------------------------------------------------------------- Visualization of trans homophilic interactions in neurons using a novel probe B6;TT2-Pcdhg<tm(floxed neo)Tyag> Tg(Gt(ROSA)26Sor-CAG-PcdhgB2-FRET)#Tyag/TyagRbrc (RBRC11902) Depositor: Takeshi Yagi, Ph.D. (Osaka University) https://mus.brc.riken.jp/en/mouse_of_month/mar_2024_mm Mouse of the Month archive https://mus.brc.riken.jp/en/mouse_of_month +----------------------------------------------------------------------- | BRC Current Technology +----------------------------------------------------------------------- 20. Fertilization using spermatocytes overcomes azoospermia caused by meiotic arrest https://mus.brc.riken.jp/en/current_tech/mar_2024 19. Establishment of nuclear transferred ES cells from wild-derived mouse leukocytes https://mus.brc.riken.jp/en/current_tech/feb_2024 BRC Current Technology archive https://mus.brc.riken.jp/en/current_tech +----------------------------------------------------------------------- | Today's model for human disease +----------------------------------------------------------------------- Sensory neurons Cre-driver mice RBRC10246 B6.129P2-Avil<tm2(cre)Faw> Homeobox gene Vsx2 Cre-driver mice RBRC09714 B6(C3)-Vsx2<tm1.1(cre/ERT2)Tfur> Homeobox gene Vsx2 Cre-driver mice RBRC06574 B6.Cg-Tg(Chx10-cre/ERT2)G7Tfur Homeobox gene Vsx2 Cre-driver mice RBRC05564 B6.Cg-Tg(Chx10-cre)G5Tfur https://mus.brc.riken.jp/en/todays_tool_and_model +----------------------------------------------------------------------- | User publications +----------------------------------------------------------------------- The following result has been newly reported by users. We are honored to introduce new publications to the science community. Therefore, we look forward to receiving your publications too. https://rrc.nbrp.jp/references/register RBRC06344 C57BL/6-App<tm3(NL-G-F)Tcs> Abdelhamid M, Jung C, Zhou C, Inoue R, Chen Y, Yoshiki Sento, Hida H, Michikawa M. Potential Therapeutic Effects of Bifidobacterium breve MCC1274 on Alzheimer’s Disease Pathologies in AppNL-G-F Mice. Nutrients. 2024, 16(4), 538. doi: 10.3390/nu16040538. https://doi.org/10.3390/nu16040538 RBRC01346 C57BL/6-Prkdc<scid>/Rbrc Zhou W, Kawashima S, Ishino T, Kawase K, Ueda Y, Yamashita K, Watanabe T, Kawazu M, Dansako H, Suzuki Y, Nishikawa H, Inozume T, Nagasaki J, Togashi Y. Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment. Cell Rep. 2024 Feb 27;43(2):113797. doi: 10.1016/j.celrep.2024.113797. https://doi.org/10.1016/j.celrep.2024.113797 RBRC00144 B6.SJL-Ptprc<a>/Rbrc Yanagi M, Ikegami I, Kamekura R, Sato T, Sato T, Kamiya S, Murayama K, Jitsukawa S, Ito F, Yorozu A, Kihara M, Abe T, Takaki H, Kawata K, Shigehara K, Miyajima S, Nishikiori H, Sato A, Tohse N, Takano KI, Chiba H, Ichimiya S. Bob1 maintains T follicular helper cells for long-term humoral immunity. Commun Biol. 2024 Feb 15;7(1):185. doi: 10.1038/s42003-024-05827-0. https://doi.org/10.1038/s42003-024-05827-0 RBRC01361 B6.Cg-Trp53<tm1Sia>/Rbrc Tokumasu R, Yasuhara R, Kang S, Funatsu T, Mishima K. Transcription factor FoxO1 regulates myoepithelial cell diversity and growth. Sci Rep. 2024 Jan 11;14(1):1069. doi: 10.1038/s41598-024-51619-1. https://doi.org/10.1038/s41598-024-51619-1 +----------------------------------------------------------------------- | Newly deposited mouse strains +----------------------------------------------------------------------- Dr. Ryoichi Matsuda, The University of Tokyo RBRC12045 B6-Tg(CAG-lacZ/TGA/luc)#Crmat RBRC12046 B6-Tg(CAG-lacZ/TAA/luc)#Crmat RBRC12047 B6-Tg(CAG-lacZ/TAG/luc)#Crmat Dr. Yoshiaki Ito, National University of Singapore RBRC12121 C57BL/6-Iqgap3<tm1.1(tdTomato)Itoy> RBRC12122 C57BL/6-Iqgap3<tm2.1(cre/ERT2)Itoy> Dr. Keiichi Itoi, Tohoku University RBRC12161 C57BL/6N-Avp<tm1.1Ksak> https://mus.brc.riken.jp/en/mailnews/kitaku_list/20240220_k __________________________________________________________________ *We hope you find the contents of this message of interest. However, if you would prefer to unsubscribe from future e-mails, please send an e-mail to animal.brc@riken.jp. *If you have any questions or comments, please send an e-mail to animal.brc@riken.jp. *Content is subject to change without notice. *All Rights Reserved. __________________________________________________________________ RIKEN BioResource Research Center Experimental Animal Division 3-1-1 Koyadai, Tsukuba-shi Ibaraki, 305-0074 Japan animal.brc@riken.jp https://mus.brc.riken.jp/en/ https://x.com/RIKEN_BRC_en __________________________________________________________________ 2024.03.12.
