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RIKEN BioResource Research Center Mouse E-mail News No. 152
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RIKEN BioResource Research Center (BRC) is pleased to update you with the
latest information.
======= Contents =======================================================
- Special topic: Mouse of the Month
"A key transcription factor for innate immunity: IRF3"
- BRC Current Technology
"Development of reproductive engineering techniques for wild-derived Spretus mice"
"Generation of chimeric mice with spermatozoa fully derived from embryonic stem cells"
"In vitro fertilization using first-wave sperm from prepubertal males"
- Today's model for human disease
- Today's tool for functional analysis
- Dr. Yuichi Obata, Senior Adviser, received the IMPC Award of Excellence for 2020
- Bioresources for COVID-19 research in RIKEN BRC
- Mouse genomic variation database has been released
- User publications
- Newly deposited mouse strains
========================================================================
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| Special topic: Mouse of the Month
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A key transcription factor for innate immunity: IRF3
RBRC10094 B6.Cg-Irf3<tm2.2Ttg>
RBRC10095 B6.Cg-Irf3<tm2.1Ttg>
Depositor: Tadatsugu Taniguchi, Ph.D. & Hideyuki Yanai, Ph.D.
University of Tokyo
https://mus.brc.riken.jp/en/mouse_of_month/nov_2020_mm
Mouse of the Month archive
https://mus.brc.riken.jp/en/mouse_of_month
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| BRC Current Technology
+-----------------------------------------------------------------------
Development of reproductive engineering techniques for wild-derived Spretus mice
https://mus.brc.riken.jp/en/current_tech/nov_2020
Generation of chimeric mice with spermatozoa fully derived from embryonic stem cells
https://mus.brc.riken.jp/en/current_tech/oct_2020
In vitro fertilization using first-wave sperm from prepubertal males
https://mus.brc.riken.jp/en/current_tech/may_2020
BRC Current Technology archive
https://mus.brc.riken.jp/en/current_tech
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| Today's model for human disease
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Human renin·human angiotensinogen double Tg mice
RBRC01122 hRN 8-12
RBRC01123 hAG 2-5
RBRC02432 (hRN8-12 x hAG2-5)F1
Prolin isomerase Pin1-KO mice
RBRC10368 B6.129P2-Pin1<tm1Tuc>
p53-target gene Tigar-KO mice
RBRC10981 B6.129-Tigar<tm1.2Smat>
Endogenous membrane protein Aqp7-KO mice
RBRC06294 B6;129-Aqp7<tm1Tfun>
Today's model for human disease
https://mus.brc.riken.jp/en/todays_tool_and_model
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| Today's tool for functional analysis
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Pro-inflammatory cytokine IL-6 KO mice
RBRC04918 B6;129S2-Il6<tm1Kopf>
RBRC04919 C;129S2-Il6<tm1Kopf>
RBRC05131 D1;129S2-Il6<tm1Kopf>
IL-6-related inflammatory status in vivo imaging mice
RBRC09487 C57BL/6N-Tyr<c-Brd>-Tg(IL6-Luc)
Human IL-6 expression conditionally controllable mice
RBRC09734 C57BL/6N-Tg(CAG-EGFP,-IL6/mCherry)29Kenw
RBRC09735 C57BL/6N-Tg(CAG-EGFP,-IL6/mCherry)56Kenw
Cre reporter mice showing green-to-red fluorescent conversion
RBRC04874 C57BL/6N-Gt(ROSA)26Sor<tm1(CAG-EGFP/tDsRed)Utr>/Rbrc
Cre reporter mice expressing EGFP signal
RBRC09806 B6.Cg-Tg(CAG-cat,-EGFP)39Miya
Cre reporter mice expressing LacZ signal
RBRC02657 B6.129P2-Gt(ROSA)26Sor<tm1(NLS-lacZ)Ito>
Today's tool for functional analysis
https://mus.brc.riken.jp/en/todays_tool_and_model
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| Dr. Yuichi Obata, Senior Adviser, received the IMPC Award of Excellence 2020
+-----------------------------------------------------------------------
At November 3rd 2020, Dr. Yuichi Obata, Senior Adviser of RIKEN BioResource Center,
received The International Mouse Phenotyping Consortium (IMPC) Award of Excellence
for 2020 for the instrumental in the RIKEN BRC joining the IMPC and importantly bringing
the IMPC to Asia and fostering IMPC activities both in Asia and further afield.
The award was announced in the Annual Fall Meeting 2020 of the Knockout Mouse
Phenotyping Project (KOMP2) & IMPC, which was held in Bethesda, USA (online).
https://web.brc.riken.jp/en/archives/news/20201104_01
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| Bioresources for COVID-19 research in RIKEN BRC
+-----------------------------------------------------------------------
Lists of mouse strains, cell lines and DNA clones useful for COVID-19 R&D
from RIKEN BRC are now available.
https://web.brc.riken.jp/en/archives/news/20201029_02
+-----------------------------------------------------------------------
| Mouse genomic variation database has been released
+-----------------------------------------------------------------------
RIKEN BioResource Research Center have released a mouse genome polymorphism database,
MoG+, mouse genome database with high added value, to promote advanced use of
experimental mice. MoG+ provides visualized mouse genomic variation among inbred mouse
strains established in Japan as well as major classical inbred strains.
MoG+
https://molossinus.brc.riken.jp/mogplus/#JF1
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| User publications
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The following result has been newly reported by users. We are
honored to introduce new publications to the science community.
Therefore, we look forward to receiving your publications too.
RBRC01828 B6.Cg-Tg(CAG-Cre)CZ-MO2Osb
Harada N, Minami Y, Hanada K, Hanaoka R, Kobayashi Y, Izawa T, Sato T,
Kato S, Inui H, Yamaji R.
Relationship between gut environment, feces-to-food ratio,
and androgen deficiency-induced metabolic disorders.
Gut Microbes. 2020 Nov 9;12(1):1817719. doi: 10.1080/19490976.2020.1817719.
https://doi.org/10.1080/19490976.2020.1817719
RBRC05658 B6.Cg-Siglech<tm1.1Ksat>
Konishi H, Okamoto T, Hara Y, Komine O, Tamada H, Maeda M, Osako F, Kobayashi M,
Nishiyama A, Kataoka Y, Takai T, Udagawa N, Jung S, Ozato K, Tamura T, Tsuda M,
Yamanaka K, Ogi T, Sato K, Kiyama H.
Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction.
EMBO J. 2020 Sep 22;e104464. doi: 10.15252/embj.2020104464.
https://doi.org/10.15252/embj.2020104464
RBRC06334
Morrice N, van Aalten L, McNeilly A, McCrimmon RJ, Pearson ER, Langston R, Sutherland C.
Reducing Glut2 throughout the body does not result in cognitive behaviour differences
in aged male mice.
BMC Res Notes. 2020 Sep 16;13(1):438. doi: 10.1186/s13104-020-05276-y.
https://doi.org/10.1186/s13104-020-05276-y
RBRC01939 B6.129X1-Trpv4<tm1Msz>
Weber J, Rajan S, Schremmer C, Chao YK, Krasteva-Christ G, Kannler M, Yildirim AÖ,
Brosien M, Schredelseker J, Weissmann N, Grimm C, Gudermann T, Dietrich A.
TRPV4 channels are essential for alveolar epithelial barrier function as protection
from lung edema.
JCI Insight. 2020 Oct 15;5(20):134464. doi: 10.1172/jci.insight.134464.
https://doi.org/10.1172/jci.insight.134464
RBRC01346 C57BL/6-Prkdc<scid>/Rbrc
Nagasaki J, Togashi Y, Sugawara T, Itami M, Yamauchi N, Yuda J, Sugano M,
Ohara Y, Minami Y, Nakamae H, Hino M, Takeuchi M, Nishikawa H.
The critical role of CD4+ T cells in PD-1 blockade against MHC-II-expressing tumors
such as classic Hodgkin lymphoma.
Blood Adv. 2020 Sep 8;4(17):4069-4082. doi: 10.1182/bloodadvances.2020002098.
https://doi.org/10.1182/bloodadvances.2020002098
RBRC00806 GFP-LC3#53
Miyake T, Sakai N, Tamai A, Sato K, Kamikawa Y, Miyagawa T, Ogura H, Yamamura Y,
Oshima M, Nakagawa S, Sagara A, Shinozaki Y, Toyama T, Kitajima S, Hara A,
Iwata Y, Shimizu M, Furuichi K, Kaneko S, Wada T.
Trehalose ameliorates peritoneal fibrosis by promoting Snail degradation
and inhibiting mesothelial-to-mesenchymal transition in mesothelial cells.
Sci Rep. 2020 Aug 31;10(1):14292. doi: 10.1038/s41598-020-71230-4.
https://doi.org/10.1038/s41598-020-71230-4
RBRC09525 C57BL/6J-Ins1<em1(cre)Utr>
Mostafa D, Yanagiya A, Georgiadou E, Wu Y, Stylianides T, Rutter GA,
Suzuki T, Yamamoto T.
Loss of Β-cell identity and diabetic phenotype in mice caused
by disruption of CNOT3-dependent mRNA deadenylation.
Commun Biol. 2020 Aug 28;3(1):476. doi: 10.1038/s42003-020-01201-y.
https://doi.org/10.1038/s42003-020-01201-y
RBRC02095 B6.B6D2-Tg (Th-EGFP)21-31Koba
Kosaka T, Pignatelli A, Kosaka K.
Heterogeneity of tyrosine hydroxylase expressing neurons
in the main olfactory bulb of the mouse.
Neurosci Res. 2020 Aug;157:15-33. doi: 10.1016/j.neures.2019.10.004.
https://doi.org/10.1016/j.neures.2019.10.004
RBRC05384 B6.Cg-Tg(Prdm14-Venus)1Sait/SaitRbrc
Grosswendt S, Kretzmer H, Smith ZD, Kumar AS, Hetzel S, Wittler L,
Klages S, Timmermann B, Mukherji S, Meissner A.
Epigenetic regulator function through mouse gastrulation.
Nature. 2020 Aug;584(7819):102-108. doi: 10.1038/s41586-020-2552-x.
https://doi.org/10.1038/s41586-020-2552-x
RBRC01345 B6.129P2-Emx1<tm1.1(cre)Ito>/ItoRbrc
Mizusawa A, Watanabe A, Yamada M, Kamei R, Shimomura Y, Kitaura Y.
BDK Deficiency in Cerebral Cortex Neurons Causes Neurological Abnormalities
and Affects Endurance Capacity.
Nutrients. 2020 Jul 29;12(8):2267. doi: 10.3390/nu12082267.
https://doi.org/10.3390/nu12082267
RBRC04895 B6(Cg)-Timd4<tm1Osa>
Min C, Park J, Kim G, Moon H, Lee SA, Kim D, Moon B, Yang S, Lee J,
Kim K, Cho H, Park J, Lee DH, Lee G, Park D.
Tim-4 functions as a scavenger receptor for phagocytosis of exogenous particles.
Cell Death Dis. 2020 Jul 23;11(7):561. doi: 10.1038/s41419-020-02773-7.
https://doi.org/10.1038/s41419-020-02773-7
RBRC01059 NC
Chen MC, Chen CS, Wu YW, Yang YY.
Poly-γ-Glutamate microneedles as transdermal immunomodulators for
ameliorating atopic dermatitis-like skin lesions in Nc/Nga mice.
Acta Biomater. 2020 Sep 15;114:183-192. doi: 10.1016/j.actbio.2020.07.029.
https://doi.org/10.1016/j.actbio.2020.07.029
RBRC05154 B6;129S6-Gt(ROSA)26Sor<tm1.1(CAG-EGFP/TeNT)Imayo>
Inagaki S, Iwata R, Iwamoto M, Imai T.
Widespread Inhibition, Antagonism, and Synergy
in Mouse Olfactory Sensory Neurons In Vivo.
Cell Rep. 2020 Jun 30;31(13):107814. doi: 10.1016/j.celrep.2020.107814.
https://doi.org/10.1016/j.celrep.2020.107814
RBRC00209 MSM/Ms
RBRC03730 B6;129S4-Dnmt3a<tm1Enl>
Yagi M, Kabata M, Tanaka A, Ukai T, Ohta S, Nakabayashi K, Shimizu M,
Hata K, Meissner A, Yamamoto T, Yamada Y.
Identification of distinct loci for de novo DNA methylation
by DNMT3A and DNMT3B during mammalian development.
Nat Commun. 2020 Jun 24;11(1):3199. doi: 10.1038/s41467-020-16989-w.
https://doi.org/10.1038/s41467-020-16989-w
RBRC05663 B6.Cg-Bcl6<tm1.1Mtto>
Chikada H, Ida K, Nishikawa Y, Inagaki Y, Kamiya A.
Liver-specific knockout of Β cell lymphoma 6 suppresses progression
of non-alcoholic steatohepatitis in mice.
Sci Rep. 2020 Jun 16;10(1):9704. doi: 10.1038/s41598-020-66539-z.
https://doi.org/10.1038/s41598-020-66539-z
RBRC02975 B6.129S-Atg5<tm1Myok>
Shen H, Zhu H, Panja D, Gu Q, Li Z.
Autophagy controls the induction and developmental decline of NMDAR-LTD
through endocytic recycling.
Nat Commun. 2020 Jun 12;11(1):2979. doi: 10.1038/s41467-020-16794-5.
https://doi.org/10.1038/s41467-020-16794-5
RBRC02192 B6.129-Mapk14<tm1.2Otsu>
Schnöder L, Gasparoni G, Nordström K, Schottek A, Tomic I,
Christmann A, Schäfer KH, Menger MD, Walter J, Fassbender K, Liu Y.
Neuronal deficiency of p38 α-MAPK ameliorates symptoms
and pathology of APP or Tau-transgenic Alzheimer's mouse models.
FASEB J. 2020 Jul;34(7):9628-9649. doi: 10.1096/fj.201902731RR.
https://doi.org/10.1096/fj.201902731RR
RBRC00445 C57BL/6-Tg(CAG/Acr-EGFP)C3-N01-FJ002Osb
Sanjo H, Yao T, Katagiri K, Sato T, Matsumura T, Komeya M, Yamanaka H,
Yao M, Matsuhisa A, Asayama Y, Ikeda K, Kano K, Aoki J, Arita M, Ogawa T.
Antioxidant vitamins and lysophospholipids are critical for
inducing mouse spermatogenesis under organ culture conditions.
FASEB J. 2020 Jul;34(7):9480-9497. doi: 10.1096/fj.202000245R.
https://doi.org/10.1096/fj.202000245R
RBRC04395 R1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>]
Pirgova G, Chauveau A, MacLean AJ, Cyster JG, Arnon TI.
Marginal zone SIGN-R1+ macrophages are essential for the maturation of
germinal center Β cells in the spleen.
Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):12295-12305. doi: 10.1073/pnas.1921673117.
https://doi.org/10.1073/pnas.1921673117
RBRC02302 B6.129P2-Lyzs<tm1(cre)Ifo>
Sato H, Taketomi Y, Miki Y, Murase R, Yamamoto K, Murakami M.
Secreted Phospholipase PLA2G2D Contributes to Metabolic Health
by Mobilizing ω3 Polyunsaturated Fatty Acids in WAT.
Cell Rep. 2020 May 5;31(5):107579. doi: 10.1016/j.celrep.2020.107579.
https://doi.org/10.1016/j.celrep.2020.107579
RBRC02388 B6.129P2-Ly96<tm1Kmiy>
Wang Y, Luo W, Han J, Khan ZA, Fang Q, Jin Y, Chen X, Zhang Y,
Wang M, Qian J, Huang W, Lum H, Wu G, Liang G.
MD2 activation by direct AGE interaction drives inflammatory diabetic cardiomyopathy.
Nat Commun. 2020 May 1;11(1):2148. doi: 10.1038/s41467-020-15978-3.
https://doi.org/10.1038/s41467-020-15978-3
RBRC04109 B6.129S6-Calca<tm1Hku>
Jiang Y, Yuan Y, Xiong Y, Wang B, Guo Y, Gong P, Zhang L.
Low-intensity pulsed ultrasound improves osseointegration of
dental implant in mice by inducing local neuronal production of αCGRP.
Arch Oral Biol. 2020 Jul;115:104736. doi: 10.1016/j.archoralbio.2020.104736.
https://doi.org/10.1016/j.archoralbio.2020.104736
RBRC06344 C57BL/6-App<tm3(NL-G-F)Tcs>
Susaki EA, Shimizu C, Kuno A, Tainaka K, Li X, Nishi K, Morishima K,
Ono H, Ode KL, Saeki Y, Miyamichi K, Isa K, Yokoyama C, Kitaura H,
Ikemura M, Ushiku T, Shimizu Y, Saito T, Saido TC, Fukayama M, Onoe H,
Touhara K, Isa T, Kakita A, Shibayama M, Ueda HR.
Versatile whole-organ/body staining and imaging based on electrolyte-gel
properties of biological tissues.
Nat Commun. 2020 Apr 27;11(1):1982. doi: 10.1038/s41467-020-15906-5.
https://doi.org/10.1038/s41467-020-15906-5
RBRC05494 B6;129P2-Tnfaip3<tm1Homy>
Montarolo F, Perga S, Tessarolo C, Spadaro M, Martire S, Bertolotto A.
TNFAIP3 Deficiency Affects Monocytes, Monocytes-Derived Cells and Microglia in Mice.
Int J Mol Sci. 2020 Apr 18;21(8):2830. doi: 10.3390/ijms21082830.
https://doi.org/10.3390/ijms21082830
RBRC02705 B6.Cg-Tg(FucciS/G2/M)#492Bsi
Weitzmann A, Naumann R, Dudeck A, Zerjatke T, Gerbaulet A, Roers A.
Mast Cells Occupy Stable Clonal Territories in Adult Steady-State Skin.
J Invest Dermatol. 2020 Apr 18;S0022-202X(20)31380-4. doi: 10.1016/j.jid.2020.03.963.
https://doi.org/10.1016/j.jid.2020.03.963
RBRC00858 B6;129S6-Bcl2l12/Irf3<tm1Ttg>/TtgRbrc
RBRC01420 B6;129P2-Irf7<tm1Ttg>/TtgRbrc
Sin WX, Yeong JP, Lim TJF, Su IH, Connolly JE, Chin KC.
IRF-7 Mediates Type I IFN Responses in Endotoxin-Challenged Mice.
Front Immunol. 2020 Apr 16;11:640. doi: 10.3389/fimmu.2020.00640.
https://doi.org/10.3389/fimmu.2020.00640
RBRC01544 B6.129P2-Sirpa<tm1Nog>/Rbrc
Cham LB, Torrez Dulgeroff LB, Tal MC, Adomati T, Li F, Bhat H, Huang A,
Lang PA, Moreno ME, Rivera JM, Galkina SA, Kosikova G, Stoddart CA,
McCune JM, Myers LM, Weissman IL, Lang KS, Hasenkrug KJ.
Immunotherapeutic Blockade of CD47 Inhibitory Signaling Enhances Innate and
Adaptive Immune Responses to Viral Infection.
Cell Rep. 2020 Apr 14;31(2):107494. doi: 10.1016/j.celrep.2020.03.058.
https://doi.org/10.1016/j.celrep.2020.03.058
RBRC00886 B6;B6C3-Tg(Acro3-EGFP)01Osb
Fukunaga H, Kaminaga K, Sato T, Watanabe R, Ogawa T, Yokoya A, Prise KM.
The Tissue-Sparing Effect of Spatially Fractionated X-rays for Maintaining
Spermatogenesis: A Radiobiological Approach for the Preservation of
Male Fertility after Radiotherapy.
J Clin Med. 2020 Apr 11;9(4):1089. doi: 10.3390/jcm9041089.
https://doi.org/10.3390/jcm9041089
RBRC00144 C57BL/6-Ly5.1
Kuroishi T, Bando K, Bakti RK, Ouchi G, Tanaka Y, Sugawara S.
Migratory dendritic cells in skin-draining lymph nodes have
nickel-binding capabilities.
Sci Rep. 2020 Mar 19;10(1):5050. doi: 10.1038/s41598-020-61875-6.
https://doi.org/10.1038/s41598-020-61875-6
RBRC06355 B6.Cg-Tg(Nes-EGFP)1Yamm
Sawada R, Nakano-Doi A, Matsuyama T, Nakagomi N, Nakagomi T.
CD44 expression in stem cells and niche microglia/macrophages
following ischemic stroke.
Stem Cell Investig. 2020 Mar 10;7:4. doi: 10.21037/sci.2020.02.02.
https://doi.org/10.21037/sci.2020.02.02
RBRC05564 B6.Cg-Tg(Chx10-cre)G5Tfur
Ikegami K, Shigeyoshi Y, Masubuchi S.
Circadian Regulation of IOP Rhythm by Dual Pathways of Glucocorticoids
and the Sympathetic Nervous System.
Invest. Ophthalmol. Vis. Sci. 2020 Mar 9;61(3):26. doi: 10.1167/iovs.61.3.26.
https://doi.org/10.1167/iovs.61.3.26
RBRC06047 B6.Cg-Hes1<tm1Imayo>
Ma Z, Xu J, Wu L, Wang J, Lin Q, Chowdhury FA, Md Mazumder HH,
Hu G, Li X, Du W.
Hes1 deficiency causes hematopoietic stem cell exhaustion.
Stem Cells. 2020 Mar 4. doi: 10.1002/stem.3169.
https://doi.org/10.1002/stem.3169
RBRC01834 C57BL/6-Tg(CAG-flpe)36Ito/ItoRbrc
Wada Y, Kikuchi A, Kaga A, Shimizu N, Ito J, Onuma R, Fujishima F,
Totsune E, Sato R, Niihori T, Shirota M, Funayama R, Sato K,
Nakazawa T, Nakayama K, Aoki Y, Aiba S, Nakagawa K, Kure S.
Metabolic and pathologic profiles of human LSS deficiency recapitulated in mice.
PLoS Genet. 2020 Feb 26;16(2):e1008628. doi: 10.1371/journal.pgen.1008628.
https://doi.org/10.1371/journal.pgen.1008628
RBRC02706 B6.Cg-Tg(FucciS/G2/M)#504Bsi
Han L, Choudhury S, Mich-Basso JD, Ammanamanchi N, Ganapathy B,
Suresh S, Khaladkar M, Singh J, Maehr R, Zuppo DA, Kim J,
Eberwine JH, Wyman SK, Wu YL, Kühn B.
Lamin B2 Levels Regulate Polyploidization of Cardiomyocyte Nuclei
and Myocardial Regeneration.
Dev Cell. 2020 Feb 26. doi: 10.1016/j.devcel.2020.01.030.
https://doi.org/10.1016/j.devcel.2020.01.030
+-----------------------------------------------------------------------
| Newly deposited mouse strains
+-----------------------------------------------------------------------
Dr. Tsuneyasu Kaisho, RIKEN
RBRC10663 B6.Cg-Xcl1<tm1.2Ksho>
RBRC10664 C.Cg-Xcr1<tm4(cre)Ksho>
RBRC10665 C.Cg-Xcr1<tm1Ksho>
RBRC11161 C57BL/6N-Arg1<tm1.1(KikGR)Ksho>
RBRC11162 C57BL/6N-Xcr1<tm5(XCR1)Ksho>
RBRC11163 B6.Cg-Spib<tm1Ksho>
RBRC11164 C.Cg-Spib<tm1Ksho>
Dr. Yoshio Fujitani, Gunma University
RBRC11097 129;B6-Pias4<em1Yfj>
Dr. Daisuke Kitamura, Tokyo University of Science
RBRC11138 B6.Cg-Blnk<tm1Dkit> Ptprc<a>
RBRC11139 B6.Cg-Dnase1l3<tm1Dkit>
RBRC11140 B6.Cg-Dnase1l3<tm1Dkit> Dffb<tm1Osa>
https://mus.brc.riken.jp/en/mailnews/kitaku_list/20201020_k
Dr. Fumihiko Horio, Nagoya University
RBRC11120 A/J-12<SM> Iah1<em1Kobam>
Dr. Takeshi Sakurai, University of Tsukuba
RBRC11137 B6J.B6N-Qrfp<tm2.1(icre)Stak>
https://mus.brc.riken.jp/en/mailnews/kitaku_list/20200924_k
Dr. William Weiss, The University of California, San Francisco
RBRC10904 129.Cg-Tg(Th-MYCN)41WawKkad
Dr. Masahito Ikawa, Osaka University
RBRC11018 B6D2-Hdgfl1<em1Osb>
RBRC11025 B6D2-Tmem97<em1Osb>
RBRC11026 B6D2-Ros1<em1Osb>
RBRC11028 B6D2-Spaca6<em2Osb>
RBRC11029 B6D2-Pithd1<em1Osb>
RBRC11035 B6D2-Fam229b<em1Osb>
RBRC11036 C57BL/6N.Cg-Adam28<em2Osb>
RBRC11038 B6D2-Nell2<em1Osb>
RBRC11044 B6D2-Ovch2<em2Osb>
RBRC11046 B6D2-Tmem95<em1Osb>
RBRC11050 B6D2-4921507P07Rik<em1Osb>
RBRC11051 B6D2-Prss51<em1Osb>
RBRC11052 B6D2-Prss55<em1Osb>
RBRC11053 B6D2-Del(9Pate1-Pate3)1Osb
RBRC11054 B6D2-Allc<em1Osb>
RBRC11063 B6D2-Fscb<em1Osb>
Dr. Mamoru Fukuchi, Takasaki University of Health and Welfare
RBRC11093 C57BL/6-Tg(RP24-310A6/Luc)2MftymMfuku
Dr. Tadashi Matsushita, Nagoya University
RBRC11096 B6.129-Myh9<tm1(R702C)Dash>
Dr. Shingo Komura, Gifu University
RBRC11098 B6.Cg-Scx<tm1.1(EGFP)Skom>
Dr. Kiyotaka Toshimori, Chiba University
RBRC11127 B6.129S2-Eqtn<tm1Ktos>
RBRC11128 B6;Cg-Tg(Eqtn-EGFP)1Ktos
https://mus.brc.riken.jp/en/mailnews/kitaku_list/20200824_k
Dr. Atsu Aiba, The University of Tokyo
RBRC11066 C57BL/6N-Del(16Pi4ka-Hira)Atai
Dr. Hideyo Ohuchi, Okayama University
RBRC11067 B6;B6CB-Fgf10<tm1Ska>
Dr. Takeshi Takarada, Okayama University
RBRC11090 C57BL6/J-Actb<em1(tetO-PA-cre)ttaka>
Dr. Akio Kihara, Hokkaido University
RBRC11099 B6.129-Elovl1<tm1Akih>
RBRC11100 B6.129-Elovl1<tm1.1Akih>
RBRC11101 C57BL/6J-Slc27a4<em1Akih>
RBRC11102 B6.Cg-Nipal4<tm1Akih>
Dr. Yoichiro Iwakura, Tokyo University of Science
RBRC11103 B6-Il17b<em1Yiw>
RBRC11104 B6-Il17d<em1Yiw>
RBRC11105 B6-C1qtnf3<tm1Yiw>
RBRC11106 C.B6-C1qtnf3<tm1Yiw>
RBRC11112 C.129P2-Cxcr4<tm1Yiw>
RBRC11113 D1.129P2-Cxcr4<tm1Yiw>
Dr. Yasuhisa Matsui, Tohoku University
RBRC11114 B6;129P2-Larp7<tm1Ymat>
RBRC11115 B6;129P2-Rest<tm1Ymat>
RBRC11116 B6.129P2-Tg(Ddx4-RFP)#15Ymat
https://mus.brc.riken.jp/en/mailnews/kitaku_list/20200720_k
Dr. Tasuku Tsukamoto, Shionogi & Co., Ltd.
RBRC10951 C57BL/6J-Tg(Col1a1-EGFP)Shi
Dr. Kazuaki Tanaka, Azabu University
RBRC10973 B6.EL-(D2Mit156-D2Mit266)/Azab
RBRC10974 B6.EL-(D2Mit365-D2Mit280)/Azab
RBRC10975 B6.EL-(D9Mit89-D9Mit38)/Azab
Dr. Tohru Yamamoto, Kagawa University
RBRC10977 B6JJcl.Cg-Mdga1<tm1.1Tymo>
RBRC10978 B6NJcl.Cg-Mdga1<tm1.1Tymo>
RBRC10979 B6JJcl.Cg-Mdga2<tm1Tymo>
RBRC10980 B6NJcl.Cg-Mdga2<tm1Tymo>
Dr. Makoto Takano, Kurume University
RBRC10983 B6.Cg-Hcn4<tm1(tTA)Nnka> Hcn4<tm1.1(Luc/EGFP)Nna>
Dr. Takayuki Sakurai, Shinshu University
RBRC10984 B6;B6D2-Tg(CAG-hCas9)2Saku
https://mus.brc.riken.jp/en/mailnews/kitaku_list/20200323_k
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2020.11.18.
