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RIKEN BioResource Research Center Mouse E-mail News No. 161
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RIKEN BioResource Research Center (BRC) is pleased to update you with the
latest information.
======= Contents =======================================================
- Special topic: Mouse of the Month
"Gata3 otic vesicle enhancer for Gata3 inner ear-specific expression"
- Today's tool for functional analysis
- BRC Current Technology
"Ultraeasy mouse sperm freezing method for everyone"
"Highly efficient generation of KO founder mice with CRISPR/Cas9"
- User publications
- Newly deposited mouse strains
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| Special topic: Mouse of the Month
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Gata3 otic vesicle enhancer for Gata3 inner ear-specific expression
RBRC10625 B6D2-Tg(Gata3/coreOVE-cre)#2481Mpu
Depositor: Takashi Moriguchi, M.D., Ph.D.
Tohoku Medical and Pharmaceutical University
https://mus.brc.riken.jp/en/mouse_of_month/aug_2021_mm
Mouse of the Month archive
https://mus.brc.riken.jp/en/mouse_of_month
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| Today's tool for functional analysis
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Cre-driver mice for inner ear
RBRC09434 B6CD1-Tg(Pax2-cre)1Akg
Cre-driver mice for olfactory sensory neurons
RBRC06339 ICR.Cg-Tg(Olfr1507-cre)1Hsak
Cre-driver mice for olfactory sensory neurons
RBRC06346 ICR.Cg-Acsm4<tm1(cre)Hsak>
Cre-driver mice for retinal photoreceptor cells and progenitor cells
RBRC05426 129.B6C3-Tg(Crx-cre)1Tfur
CreERT2-driver mice for retinal photoreceptor cells and progenitor cells
RBRC05559 B6.Cg-Tg(Crx-cre/ERT2)1Tfur
Today's tool for functional analysis
https://mus.brc.riken.jp/en/todays_tool_and_model
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| BRC Current Technology
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Ultraeasy mouse sperm freezing method for everyone
https://mus.brc.riken.jp/en/current_tech/jul_2021
Highly efficient generation of KO founder mice with CRISPR/Cas9
https://mus.brc.riken.jp/en/current_tech/aug_2021
BRC Current Technology archive
https://mus.brc.riken.jp/en/current_tech
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| User publications
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The following result has been newly reported by users. We are
honored to introduce new publications to the science community.
Therefore, we look forward to receiving your publications too.
RBRC05808 B6.129P2-Aldh2<tm1Kaw>
Xu T, Guo J, Wei M, Wang J, Yang K, Pan C, Pang J, Xue L, Yuan QH, Xue M,
Zhang J, Sang W, Jiang T, Chen Y, Xu F.
Aldehyde dehydrogenase 2 protects against acute kidney injury by
regulating autophagy via Beclin-1 pathway.
JCI Insight. 2021 Jul 6;138183. doi: 10.1172/jci.insight.138183.
https://doi.org/10.1172/jci.insight.138183
RBRC01474 B6.129-Fas<tm1Osa>/OsaRbrc
Jeong D, Kim HS, Kim HY, Kang MJ, Jung H, Oh Y, Kim D, Koh J, Cho SY, Jeon YK,
Lee EB, Lee SH, Shin EC, Kim HM, Yi EC, Chung DH.
Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2.
Elife. 2021 Jul 5;10:e48840. doi: 10.7554/eLife.48840.
https://doi.org/10.7554/eLife.48840
RBRC02192 B6.129-Mapk14<tm1.2Otsu>
Schnöder L, Tomic I, Schwindt L, Helm D, Rettel M, Schulz-Schaeffer W, Krause E,
Rettig J, Fassbender K, Liu Y.
P38α-MAPK phosphorylates Snapin and reduces Snapin-mediated BACE1
transportation in APP-transgenic mice.
FASEB J. 2021 Jul;35(7):e21691. doi: 10.1096/fj.202100017R.
https://doi.org/10.1096/fj.202100017R
RBRC05658 B6.Cg-Siglech<tm1.1Ksat>
Li C, Konishi H, Nishiwaki K, Sato K, Miyata T, Kiyama H.
A mouse model of microglia-specific ablation in the embryonic central nervous system.
Neurosci Res. 2021 Jun 23;S0168-0102(21)00143-7. doi: 10.1016/j.neures.2021.06.002.
https://doi.org/10.1016/j.neures.2021.06.002
RBRC04874 C57BL/6N-Gt(ROSA)26Sor<tm1(CAG-EGFP/tDsRed)Utr>/Rbrc
Mizoguchi A, Banno R, Sun R, Yaginuma H, Taki K, Kobayashi T, Sugiyama M,
Tsunekawa T, Onoue T, Takagi H, Hagiwara D, Ito Y, Iwama S, Suga H,
Nagai T, Yamada K, Arima H.
Glucocorticoid receptor signaling in ventral tegmental area neurons increases
the rewarding value of a high-fat diet in mice.
Sci Rep. 2021 Jun 18;11(1):12873. doi: 10.1038/s41598-021-92386-7.
https://doi.org/10.1038/s41598-021-92386-7
RBRC00985
Nijholt KT, Meems LMG, Ruifrok WPT, Maass AH, Yurista SR, Pavez-Giani MG,
Mahmoud B, Wolters AHG, van Veldhuisen DJ, van Gilst WH, Silljé HHW,
de Boer RA, Westenbrink BD.
The erythropoietin receptor expressed in skeletal muscle is essential for
mitochondrial biogenesis and physiological exercise.
Pflugers Arch. 2021 Aug;473(8):1301-1313. doi: 10.1007/s00424-021-02577-4.
https://doi.org/10.1007/s00424-021-02577-4
RBRC05603 B6.FVB-Tg(Col1a1-cre)1Kry
Yoshioka H, Okita S, Nakano M, Minamizaki T, Nubukiyo A, Sotomaru Y,
Bonnelye E, Kozai K, Tanimoto K, Aubin JE, Yoshiko Y.
Single-Cell RNA-Sequencing Reveals the Breadth of Osteoblast Heterogeneity.
JBMR Plus. 2021 May 17;5(6):e10496. doi: 10.1002/jbm4.10496.
https://doi.org/10.1002/jbm4.10496
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| Newly deposited mouse strains
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Dr. Akiharu Kubo, Keio University
RBRC11198 B6;Cg-Cdc20<em1(R286S)Jko>
RBRC11199 B6;Cg-Cdc20<em2Jko>
Dr. Masabumi Shibuya, Jobu University
RBRC11431 B6;Cg-Flt1<tm1Msh>
RBRC11432 B6;Cg-Flt1<tm2Msh>
RBRC11433 B6;129-Kdr<tm1.1Msh>
RBRC11434 B6;129-Kdr<tm2.1Msh>
Dr. Hiroyuki Tomita, Gifu University
RBRC11435 B6;Cg-Col1a1<tm3(tetO-Fgf10,-tdTomato)Hirt>
Dr. Atsushi Enomoto, Nagoya University
RBRC11436 B6.129S6-Islr<tm1.1(cre/ERT2)Mat>
Dr. Atsu Aiba, The University of Tokyo
RBRC11446 C57BL/6J-Lamp5<em1Atai>
https://mus.brc.riken.jp/en/mailnews/kitaku_list/20210720_k
__________________________________________________________________
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__________________________________________________________________
RIKEN BioResource Research Center
Experimental Animal Division
3-1-1 Koyadai, Tsukuba-shi
Ibaraki, 305-0074 Japan
animal.brc@riken.jp
https://mus.brc.riken.jp/en/
__________________________________________________________________
2021.08.17.
