************************************************************************ RIKEN BioResource Research Center Mouse E-mail News No. 164 ************************************************************************ RIKEN BioResource Research Center (BRC) is pleased to update you with the latest information. ======= Contents ======================================================= - Special topic: Mouse of the Month "A model mouse strain for 22q11.2 deletion syndrome with a 3.0-Mb deletion" - Today's model for human disease - User publications - Newly deposited mouse strains ======================================================================== +----------------------------------------------------------------------- | Special topic: Mouse of the Month +----------------------------------------------------------------------- A model mouse strain for 22q11.2 deletion syndrome with a 3.0-Mb deletion RBRC11066 C57BL/6N-Del(16Pi4ka-Hira)Atai Depositor: Atsu Aiba, Ph.D. The University of Tokyo https://mus.brc.riken.jp/en/mouse_of_month/nov_2021_mm Mouse of the Month archive https://mus.brc.riken.jp/en/mouse_of_month +----------------------------------------------------------------------- | Today's model for human disease +----------------------------------------------------------------------- Major components of stratum corneum Flg (filaggrin) gene KO mice RBRC05850 B6.Cg-Flg<tm1> RBRC05851 C.Cg-Flg<tm1> GPI-anchored membrane protein Cd109 gene KO mice RBRC09599 FVB.129S6-Cd109<tm1Mat> Foxp2[R552H] KI mice RBRC04059 B6;129S6-Foxp2<tm1Momo> RBRC04060 129S6/SvEvTac-Foxp2<tm1Momo> GPI-anchored membrane protein Mdga1 KO mice RBRC05286 Mdga1 (Acc. No.CDB0454K) RBRC10977 B6JJcl.Cg-Mdga1<tm1.1Tymo> RBRC10978 B6NJcl.Cg-Mdga1<tm1.1Tymo> Today's model for human disease https://mus.brc.riken.jp/en/todays_tool_and_model +----------------------------------------------------------------------- | User publications +----------------------------------------------------------------------- The following result has been newly reported by users. We are honored to introduce new publications to the science community. Therefore, we look forward to receiving your publications too. RBRC02657 B6.129P2-Gt(ROSA)26Sor<tm1(NLS-lacZ)Ito> Namiki T, Kamoshita M, Kageyama A, Terakawa J, Ito J, Kashiwazaki N. Utility of progesterone receptor-ires-Cre to generate conditional knockout mice for uterine study. Anim Sci J. 2021 Dec;92(1):e13615. doi: 10.1111/asj.13615. https://doi.org/10.1111/asj.13615 RBRC00169 B6.Cg-Tnc<tm1Sia>/Rbrc Xu M, Ye Z, Zhao X, Guo H, Gong X, Huang R. Deficiency of tenascin-C attenuated cardiac injury by inactivating TLR4/NLRP3/caspase-1 pathway after myocardial infarction. Cell Signal. 2021 Oct;86:110084. doi: 10.1016/j.cellsig.2021.110084. https://doi.org/10.1016/j.cellsig.2021.110084 RBRC00107 C3.Cg-Trp53<tm1Sia>/Rbrc Machida Y, Imai T. Different properties of mammary carcinogenesis induced by two chemical carcinogens, DMBA and PhIP, in heterozygous BALB/c Trp53 knockout mice. Oncol Lett. 2021 Oct;22(4):738. doi: 10.3892/ol.2021.12999. https://doi.org/10.3892/ol.2021.12999 +----------------------------------------------------------------------- | Newly deposited mouse strains +----------------------------------------------------------------------- Drs. Shigeo Koyasu and Kazuyo Moro, RIKEN IMS RBRC11203 B6-Rora<tm1.1Shkm> Dr. Tsuneyasu Kaisho, RIKEN IMS RBRC11400 C.Cg-Spib<tm2.1Ksho> Dr. Akio Kihara, Hokkaido University RBRC11422 B6-Cyp4f39<em1Akih> Dr. Takashi Iwamoto, Chubu University RBRC11511 B6.C3H-In(6)1J Mitf<em1Chuan> Dr. Sho Kakizawa, Kyoto University RBRC11531 STOCK Shc2<tm1Paw> Dr. Ayako Isotani, Nara Institute of Science and Technology RBRC11533 B6D2F1;B6-Ets2<em1Aitn> RBRC11535 B6;129B6-Tg(CAG-Su9/tdTomato/T2A/Puro)1GAitn Dr. Akio Kihara, Hokkaido University RBRC11538 B6-Awat1<em1Akih> RBRC11539 B6-Awat2<em1Akih> Dr. Atsu Aiba, The University of Tokyo RBRC11544 C57BL/6N-Del(16Pi4ka-Dgcr2)Atai RBRC11545 C57BL/6N-Del(16Dgcr2-Hira)Atai The Scripps Research Institute Dr. Benjamin F. Cravatt RBRC11546 B6;129S-Ppme1<tm1Crv> Dr. Tadafumi Kato, RIKEN CBS RBRC11547 B6-Ntrk1<tm1(E495K)Tkato> RBRC11548 B6-Ntrk1<em1(E495K)Tkato>/KN2 RBRC11549 B6-Ntrk1<em2(E495K)Tkato>/KN5 RBRC11550 B6-Ntrk1<em3Tkato>/KN7 RBRC11551 B6-Ntrk1<em4Tkato>/KN9 RBRC11552 B6-Ntrk1<em5Tkato>/KN6 Drs. Toshitada Takemori and Takashi Tanaka, RIKEN IMS RBRC11554 B6.Cg-Bcl2l11<tm1.1Mtto> https://mus.brc.riken.jp/en/mailnews/kitaku_list/20211020_k __________________________________________________________________ *We hope you find the contents of this message of interest. However, if you would prefer to unsubscribe from future e-mails, please send an e-mail to animal.brc@riken.jp. *If you have any questions or comments, please send an e-mail to animal.brc@riken.jp. *Content is subject to change without notice. *All Rights Reserved. __________________________________________________________________ RIKEN BioResource Research Center Experimental Animal Division 3-1-1 Koyadai, Tsukuba-shi Ibaraki, 305-0074 Japan animal.brc@riken.jp https://mus.brc.riken.jp/en/ __________________________________________________________________ 2021.11.12.