RIKEN BioResource Research Center Mouse E-mail News No. 164

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RIKEN BioResource Research Center Mouse E-mail News No. 164
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RIKEN BioResource Research Center (BRC) is pleased to update you with the 
latest information.

======= Contents =======================================================
- Special topic: Mouse of the Month
  "A model mouse strain for 22q11.2 deletion syndrome with a 3.0-Mb deletion"
- Today's model for human disease
- User publications
- Newly deposited mouse strains
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| Special topic: Mouse of the Month
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A model mouse strain for 22q11.2 deletion syndrome with a 3.0-Mb deletion
  RBRC11066 C57BL/6N-Del(16Pi4ka-Hira)Atai
 
Depositor: Atsu Aiba, Ph.D.
           The University of Tokyo
                    
 https://mus.brc.riken.jp/en/mouse_of_month/nov_2021_mm

Mouse of the Month archive
 https://mus.brc.riken.jp/en/mouse_of_month


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| Today's model for human disease
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Major components of stratum corneum Flg (filaggrin) gene KO mice
RBRC05850 B6.Cg-Flg<tm1>
RBRC05851 C.Cg-Flg<tm1>

GPI-anchored membrane protein Cd109 gene KO mice
RBRC09599 FVB.129S6-Cd109<tm1Mat>

Foxp2[R552H] KI mice
RBRC04059 B6;129S6-Foxp2<tm1Momo>
RBRC04060 129S6/SvEvTac-Foxp2<tm1Momo>

GPI-anchored membrane protein Mdga1 KO mice
RBRC05286 Mdga1 (Acc. No.CDB0454K)
RBRC10977 B6JJcl.Cg-Mdga1<tm1.1Tymo>
RBRC10978 B6NJcl.Cg-Mdga1<tm1.1Tymo>

Today's model for human disease
 https://mus.brc.riken.jp/en/todays_tool_and_model


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| User publications
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 The following result has been newly reported by users. We are
honored to introduce new publications to the science community.
Therefore, we look forward to receiving your publications too.

RBRC02657 B6.129P2-Gt(ROSA)26Sor<tm1(NLS-lacZ)Ito>
Namiki T, Kamoshita M, Kageyama A, Terakawa J, Ito J, Kashiwazaki N.
Utility of progesterone receptor-ires-Cre to generate conditional 
knockout mice for uterine study.
Anim Sci J. 2021 Dec;92(1):e13615. doi: 10.1111/asj.13615.
https://doi.org/10.1111/asj.13615

RBRC00169 B6.Cg-Tnc<tm1Sia>/Rbrc
Xu M, Ye Z, Zhao X, Guo H, Gong X, Huang R.
Deficiency of tenascin-C attenuated cardiac injury by inactivating 
TLR4/NLRP3/caspase-1 pathway after myocardial infarction.
Cell Signal. 2021 Oct;86:110084. doi: 10.1016/j.cellsig.2021.110084.
https://doi.org/10.1016/j.cellsig.2021.110084

RBRC00107 C3.Cg-Trp53<tm1Sia>/Rbrc
Machida Y, Imai T.
Different properties of mammary carcinogenesis induced by 
two chemical carcinogens, DMBA and PhIP, in heterozygous BALB/c Trp53 knockout mice.
Oncol Lett. 2021 Oct;22(4):738. doi: 10.3892/ol.2021.12999.
https://doi.org/10.3892/ol.2021.12999


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| Newly deposited mouse strains
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Drs. Shigeo Koyasu and Kazuyo Moro, RIKEN IMS
RBRC11203 B6-Rora<tm1.1Shkm>

Dr. Tsuneyasu Kaisho, RIKEN IMS
RBRC11400 C.Cg-Spib<tm2.1Ksho>

Dr. Akio Kihara, Hokkaido University
RBRC11422 B6-Cyp4f39<em1Akih>

Dr. Takashi Iwamoto, Chubu University
RBRC11511 B6.C3H-In(6)1J Mitf<em1Chuan>

Dr. Sho Kakizawa, Kyoto University
RBRC11531 STOCK Shc2<tm1Paw>

Dr. Ayako Isotani, Nara Institute of Science and Technology
RBRC11533 B6D2F1;B6-Ets2<em1Aitn>
RBRC11535 B6;129B6-Tg(CAG-Su9/tdTomato/T2A/Puro)1GAitn

Dr. Akio Kihara, Hokkaido University
RBRC11538 B6-Awat1<em1Akih>
RBRC11539 B6-Awat2<em1Akih>

Dr. Atsu Aiba, The University of Tokyo
RBRC11544 C57BL/6N-Del(16Pi4ka-Dgcr2)Atai
RBRC11545 C57BL/6N-Del(16Dgcr2-Hira)Atai

The Scripps Research Institute	Dr. Benjamin F. Cravatt
RBRC11546 B6;129S-Ppme1<tm1Crv>

Dr. Tadafumi Kato, RIKEN CBS	
RBRC11547 B6-Ntrk1<tm1(E495K)Tkato>
RBRC11548 B6-Ntrk1<em1(E495K)Tkato>/KN2
RBRC11549 B6-Ntrk1<em2(E495K)Tkato>/KN5
RBRC11550 B6-Ntrk1<em3Tkato>/KN7
RBRC11551 B6-Ntrk1<em4Tkato>/KN9
RBRC11552 B6-Ntrk1<em5Tkato>/KN6

Drs. Toshitada Takemori and Takashi Tanaka, RIKEN IMS
RBRC11554 B6.Cg-Bcl2l11<tm1.1Mtto>

https://mus.brc.riken.jp/en/mailnews/kitaku_list/20211020_k


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__________________________________________________________________
RIKEN BioResource Research Center
Experimental Animal Division
3-1-1 Koyadai, Tsukuba-shi
Ibaraki, 305-0074 Japan
animal.brc@riken.jp
https://mus.brc.riken.jp/en/
__________________________________________________________________
2021.11.12.


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