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RIKEN BioResource Research Center Mouse E-mail News No. 167
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RIKEN BioResource Research Center (BRC) is pleased to update you with the
latest information.
======= Contents =======================================================
- Special topic: Mouse of the Month
"A novel protein knockdown technology: auxin-inducible degron (AID) 2 system"
- Today's tool for functional analysis
- User publications
- Newly deposited mouse strains
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| Special topic: Mouse of the Month
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A novel protein knockdown technology: auxin-inducible degron (AID) 2 system
RBRC11438 B6;B6D2-Tg(CAG-OsTIR1-P2A-mAID-EGFP-nanoluc)#16Ysa
RBRC11439 B6;B6D2-Tg(CAG-OsTIR1-P2A-mAID-EGFP-nanoluc)#19Ysa
Depositor: Yumiko Saga, Ph.D.
National Institute of Genetics
https://mus.brc.riken.jp/en/mouse_of_month/feb_2022_mm
NBRP Fundamental Technology Upgrading Program
https://nbrp.jp/en/achievements-en/basic-technology-task-list-en
Mouse of the Month archive
https://mus.brc.riken.jp/en/mouse_of_month
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| Today's tool for functional analysis
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Actin-tTS Tg mice
RBRC05447 B6.Cg-Tg(ACTB-tTS)1Mllo
Gad1-tTA KI mice
RBRC11365 B6;Cg-Gad1<tm1.1(tTA2)Kftnk>
Gad1-Stop-tetO KI mice
RBRC11364 B6-Gad1<tm1(tetO)Ksak>
Nkcc1-tetO KI mice
RBRC11202 STOCK Slc12a2<tm1.1(tetO)Kftnk>
CatC-tetO KI mice
RBRC10854 C57BL/6N-Ctsc<tm1.1Ike>
Today's tool for functional analysis
https://mus.brc.riken.jp/en/todays_tool_and_model
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| User publications
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The following result has been newly reported by users. We are
honored to introduce new publications to the science community.
Therefore, we look forward to receiving your publications too.
https://rrc.nbrp.jp/references/register
RBRC06239 C57BL/6-Siglec1<tm1(cre)Mtka>
Camara A, Lavanant AC, Abe J, Desforges HL, Alexandre YO, Girardi E,
Igamberdieva Z, Asano K, Tanaka M, Hehlgans T, Pfeffer K, Pfeffer S,
Mueller SN, Stein JV, Mueller CG.
CD169+ macrophages in lymph node and spleen critically depend on
dual RANK and LTbetaR signaling.
Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2108540119. doi: 10.1073/pnas.2108540119.
https://doi.org/10.1073/pnas.2108540119
RBRC09595 B6.129P2-Keap1<tm2Mym>
Vallelian F, Buzzi RM, Pfefferlé M, Yalamanoglu A, Dubach IL, Wassmer A,
Gentinetta T, Hansen K, Humar R, Schulthess N, Schaer CA, Schaer DJ.
Heme-stress activated NRF2 skews fate trajectories of bone marrow cells
from dendritic cells towards red pulp-like macrophages in hemolytic anemia.
Cell Death Differ. 2022 Jan 14. doi: 10.1038/s41418-022-00932-1.
https://doi.org/10.1038/s41418-022-00932-1
RBRC00806 GFP-LC3#53
Goldsmith J, Ordureau A, Harper JW, Holzbaur ELF.
Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched
mitochondrial fragments by basal autophagy in neurons.
Neuron. 2022 Jan 13;S0896-6273(21)01046-1. doi: 10.1016/j.neuron.2021.12.029.
https://doi.org/10.1016/j.neuron.2021.12.029
RBRC06344 C57BL/6-App<tm3(NL-G-F)Tcs>
Murakami A, Hara T, Yamada-Kubota C, Kuwahara M, Ichikawa T, Minagi S.
Lack of occlusal support did not impact amyloid β deposition in APP knock-in mice.
J Prosthodont Res. 2022 Jan 11;66(1):161-166. doi: 10.2186/jpr.JPR_D_20_00205.
https://doi.org/10.2186/jpr.JPR_D_20_00205
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| Newly deposited mouse strains
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Dr. Atsushi Enomoto, Nagoya University
RBRC11437 B6.129S6-Islr<tm1.1(ZsGreen/DTR/cre)Mat>
https://mus.brc.riken.jp/ja/mailnews/kitaku_list/20220120_k
__________________________________________________________________
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__________________________________________________________________
RIKEN BioResource Research Center
Experimental Animal Division
3-1-1 Koyadai, Tsukuba-shi
Ibaraki, 305-0074 Japan
animal.brc@riken.jp
https://mus.brc.riken.jp/en/
__________________________________________________________________
2022.02.16.
