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BRC Mouse E-mail News No. 188
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RIKEN BioResource Research Center (BRC) is pleased to update you with the
latest information.
======= Contents =======================================================
- Mouse of the Month
"A novel luminescent Tg strain expressing emerald luciferase"
- Today's model for human disease
- User publications
- Newly deposited mouse strains
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| Mouse of the Month
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A novel luminescent Tg strain expressing emerald luciferase
C57BL/6-Tg(CAG-ELuc)1Nkzom (RBRC11951)
Depositors: Fuminori Taniguchi, M.D., Ph.D. and Kazuomi Nakamura, Ph.D.
(Tottori University)
https://mus.brc.riken.jp/en/mouse_of_month/jan_2024_mm
Mouse of the Month archive
https://mus.brc.riken.jp/en/mouse_of_month
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| Today's model for human disease
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Kpna1(importin α5) gene KO mice
RBRC06031 B6.129S2-Kpna1<tm1.2Yyo>
RBRC06030 B6;129S2-Kpna1<tm1.1Yyo>
Kiss1 gene floxed mice
RBRC10389 ICR.Cg-Kiss1<tm1.1Nurep>
Prl gene KO mice
RBRC06232 B6.129S2-Prl<tm1Hmn>
https://mus.brc.riken.jp/en/todays_tool_and_model
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| User publications
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The following result has been newly reported by users. We are
honored to introduce new publications to the science community.
Therefore, we look forward to receiving your publications too.
https://rrc.nbrp.jp/references/register
RBRC06344 C57BL/6-App<tm3(NL-G-F)Tcs>
Yamada H, Yamazaki Y, Takebayashi Y, Yazawa K, Sasanishi M, Motoda A, Nakamori M, Morino H, Takahashi T, Maruyama H.
The long-term effects of heated tobacco product exposure on the central nervous system in a mouse model of prodromal Alzheimer's disease.
Sci Rep. 2024 Jan 2;14(1):227. doi: 10.1038/s41598-023-50941-4.
https://doi.org/10.1038/s41598-023-50941-4
RBRC00858 B6;129S6-Bcl2l12/Irf3<tm1Ttg>/TtgRbrc
Ines Ambite, Thi Hien Tran, Daniel S.C. Butler, Michele Cavalera, Murphy Lam Yim Wan, Shahram Ahmadi, Catharina Svanborg.
Therapeutic Effects of IL-1RA against Acute Bacterial Infections, including Antibiotic-Resistant Strains.
Pathogens. 2024;13(1):42. doi: 10.3390/pathogens13010042.
https://doi.org/10.3390/pathogens13010042
RBRC04395 B6;129-Siglec1<tm1(HBEGF)Mtka>
Casella V, Domenjo-Vila E, Esteve-Codina A, Pedragosa M, Cebollada Rica P, Vidal E, de la Rubia I, López-Rodríguez C, Bocharov G, Argilaguet J, Meyerhans A.
Differential kinetics of splenic CD169+ macrophage death is one underlying cause of virus infection fate regulation.
Cell Death Dis. 2023 Dec 18;14(12):838. doi: 10.1038/s41419-023-06374-y.
https://doi.org/10.1038/s41419-023-06374-y
RBRC02759 B6.Cg-Atg7<tm1Tchi>
Yan B, Belke D, Gui Y, Chen YX, Jiang ZS, Zheng XL.
Pharmacological inhibition of MALT1 (mucosa-associated lymphoid tissue lymphoma translocation protein 1) induces ferroptosis in vascular smooth muscle cells.
Cell Death Discov. 2023 Dec 15;9(1):456. doi: 10.1038/s41420-023-01748-9.
https://doi.org/10.1038/s41420-023-01748-9
RBRC02759 B6.Cg-Atg7<tm1Tchi>
Parham LR, Williams PA, Katada K, Nettleford SK, Chatterji P, Acheampong KK, Danan CH, Ma X, Simon LA, Naughton KE, Karakasheva T, McMillan EA, Whelan KA, Brady DC, Shaffer SM, Hamilton KE.
IGF2BP1/IMP1 deletion enhances a facultative stem cell state via regulation of MAP1LC3B.
Cell Mol Gastroenterol Hepatol. 2023 Dec 9:S2352-345X(23)00214-X. doi: 10.1016/j.jcmgh.2023.12.001.
https://doi.org/10.1016/j.jcmgh.2023.12.001
RBRC01828 B6.Cg-Tg(CAG-Cre)CZ-MO2Osb
RCB0466 Lu-134-A
RCB0469 Lu-139
RCB1184 Lu-165
RCB2281 T3M-12
RCB2092 87-5
RCB0725 MS-1
RCB1966 S1
RCB0098 A549
RCB2143 DU145
RCB2144 LNCap.FGC
RCB2202 293T
Nomura M, Ohuchi M, Sakamoto Y, Kudo K, Yaku K, Soga T, Sugiura Y, Morita M, Hayashi K, Miyahara S, Sato T, Yamashita Y, Ito S, Kikuchi N, Sato I, Saito R, Yaegashi N, Fukuhara T, Yamada H, Shima H, Nakayama KI, Hirao A, Kawasaki K, Arai Y, Akamatsu S, Tanuma SI, Sato T, Nakagawa T, Tanuma N.
Niacin restriction with NAMPT-inhibition is synthetic lethal to neuroendocrine carcinoma.
Nat Commun. 2023 Dec 13;14(1):8095. doi: 10.1038/s41467-023-43630-3.
https://doi.org/10.1038/s41467-023-43630-3
RBRC00144 B6.SJL-Ptprc<a>/Rbrc
Tokifuji Y, Hayabuchi H, Sasaki T, Hara-Chikuma M, Hirota K, Takahashi H, Amagai M, Yoshimura A, Chikuma S.
Targeting abatacept-resistant T-helper-17 cells by aldehyde dehydrogenase inhibition.
iScience. 2023 Dec 1;08646. doi:10.1016/j.isci.2023.108646.
https://doi.org/10.1016/j.isci.2023.108646
RBRC02370 B6.129-Grn<tm1Mni>
Sasaki T, Kuse Y, Nakamura S, Shimazawa M.
Progranulin-deficient macrophages cause cardiotoxicity under hypoxic conditions.
Biochem Biophys Res Commun. 2024 Jan 8:691:149341.
doi: 10.1016/j.bbrc.2023.149341.
https://doi.org/10.1016/j.bbrc.2023.149341
RBRC10972 B6.Cg-Serpinh1<tm2Kzn>
Shin J, Toyoda S, Okuno Y, Hayashi R, Nishitani S, Onodera T, Sakamoto H, Ito S, Kobayashi S, Nagao H, Kita S, Otsuki M, Fukuhara A, Nagata K, Shimomura I.
HSP47 levels determine the degree of body adiposity.
Nat Commun. 2023 Nov 11;14(1):7319. doi: 10.1038/s41467-023-43080-x.
https://doi.org/10.1038/s41467-023-43080-x
RBRC01420 B6;129P2-Irf7<tm1Ttg>/TtgRbrc
Yang Y, Kumar V, Peng W, Fijak M, Gabriela M, Cai W, Meinhardt A, Bhushan S.
Role of Macrophage Colony Stimulating Factor and Interferon Regulatory Factor 7 in Modulating the Immune Profile of Mouse Testicular Macrophages.
Journal of Reproductive Immunology. 2023 Nov 1;104169. doi: 10.1016/j.jri.2023.104169.
https://doi.org/10.1016/j.jri.2023.104169
RBRC02975 B6.129S-Atg5<tm1Myok>
Cheng J, Wang Y, Yin L, Liang W, Zhang J, Ma C, Zhang Y, Liu B, Wang J, Zhao W, Li M, Wei L.
The nonstructural protein 1 of respiratory syncytial virus hijacks host mitophagy as a novel mitophagy receptor to evade the type I IFN response in HEp-2 cells.
mBio. 2023 Nov 1;14(6):e0148023. doi: 10.1128/mbio.01480-23.
https://doi.org/10.1128/mbio.01480-23
RBRC03556 B6.129-Dmd<tm1Mok>
Motohashi N, Minegishi K, Aoki Y.
Inherited myogenic abilities in muscle precursor cells defined by the mitochondrial complex I-encoding protein.
Cell Death Dis. 2023 Oct 19;14(10):689. doi: 10.1038/s41419-023-06192-2.
https://doi.org/10.1038/s41419-023-06192-2
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| Newly deposited mouse strains
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Dr. Tsukasa Ohmori, Jichi Medical University
RBRC12135 C57BL/6-F9<tm2.1(hF9_R338L_I316T)Tsuka>
Dr. Kohichi Tanaka, Tokyo Medical and Dental University
RBRC12138 C57BL/6J-Emx1<em1(dre)Kta>
RBRC12140 B6.129-Slc1a3<tm1Kta>
Dr. Takayoshi Inoue, National Center of Neurology and Psychiatry
RBRC12156 B6;Cg-Oxtr<em4(3xHA/T2A/icre/ERT2)Yinn>/#8
https://mus.brc.riken.jp/en/mailnews/kitaku_list/20231220_k
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__________________________________________________________________
RIKEN BioResource Research Center
Experimental Animal Division
3-1-1 Koyadai, Tsukuba-shi
Ibaraki, 305-0074 Japan
animal.brc@riken.jp
https://mus.brc.riken.jp/en/
https://x.com/RIKEN_BRC_en
__________________________________________________________________
2024.01.16.
