A Japanese wild-derived inbred strain for functional genomics
MSM (RBRC00209) is a wild-derived inbred strain originated from Japanese wild mice,Mus musculus molossinus . The MSM mice have several unique phenotypes, such as small body size (<15 grams), low incidence of tumor development, and distinct behaviors, making them promising resources for higher brain functions and lifestyle-related diseases by expanding genome diversity. The MSM is especially invaluable for uncovering novel functions of the genome by the availability of the MSM genomic BAC libraries , whole genome sequence information , microsatellite marker data , consomic strains with C57BL/6 background , and germ cell competent ES cells . Thus, the MSM expands the range of the genetic variations of laboratory mouse strains.