今月のマウス・バックナンバー 2023 Feb 2023 Gal4/UAS発現システム依存的な遺伝子組み換えと細胞イメージングが可能なマウス Jan 2023 B細胞で発現するCreドライバーマウス 2022 Nov 2022 RASopathies(RAS/MAPK症候群)モデルマウス Oct 2022 生殖細胞系列で発現するCreドライバーマウス Aug 2022 オキシトシン産生ニューロンCreドライバーマウス Jun 2022 がん研究注目の因子Meflin(Islr)機能解析ツール Apr 2022 重複せずに三胚葉を蛍光標識可能なTRiCKマウス Mar 2022 時空間特異的遺伝子組み換えを可能にする新規Creドライバーマウス Feb 2022 新規タンパク質ノックダウン技術オーキシンデグロン(AID) 2法 2021 Nov 2021 3.0-Mb欠失を再現した22q11.2欠失症候群モデルマウス Oct 2021 新規白質消失病モデルtoyマウス Sep 2021 マウスでの冬眠様状態の誘導 Aug 2021 内耳特異的にGata3遺伝子の発現を制御するエンハンサー配列Gata3 OVE May 2021 効率的なゲノム編集マウス作製実現のため開発されたCas9 Tgマウス Mar 2021 染色体工学技術を用いて作製された新規ダウン症候群モデルマウス Feb 2021 Ucp1 in vivoイメージングマウス 2020 Dec 2020 光変換により細胞動態をモニター可能なKaedeマウス Nov 2020 自然免疫応答を制御する転写因子：IRF3 Mar 2020 パイロトーシス実行因子: ガスダーミンD Feb 2020 In vivo イメージングに有用な新規ヘアレスマウス 2019 Dec 2019 グリシン作動性ニューロンCreドライバーマウス Nov 2019 ENUミュータジェネシスによって樹立されたGLUT1欠損症モデルマウス Oct 2019 特定ゲノム領域上の分子間相互作用解析に有用な3xFLAG-dCas9発現マウス Aug 2019 造血幹細胞の自己複製を制御するPHF6 Jul 2019 熱ストレス応答だけでない、様々な場面で機能する転写因子Heat shock transcription factor 1 (HSF1) Jun 2019 血友病Bモデルマウス Apr 2019 痛覚異常を示すZfhx2遺伝子欠損マウス Mar 2019 Long-sleep mouse model induced by Sik3 splice mutation Feb 2019 iRFP transgenic mice for in vivo imaging Jan 2019 Bcl6 reporter mice for immune memory research 2018 Dec 2018 Bicistronic Insulin1-Cre knock-in mice Nov 2018 Autism spectrum disorder (ASD) model mice Oct 2018 Green-to-red fluorescent-convertible Cre-reporter mice 2017 Sep 2017 RAQP4, the main subset of the aquaporin water channel family in the brain Aug 2017 Transcranial imaging of intracellular Ca2+ in astrocytes and neurons Jun 2017 A tool for understanding endogenous sphingolipid synthesis Apr 2017 Regulatory function of nuclear protein IκB-ζ in inflammatory responses Mar 2017 Identifying pheromone circuits in mice Feb 2017 Cell type-specific expression of photoconvertible fluorescent protein KikGR 2016 Oct 2016 Autophagy monitoring congjaic strains Oct 2016 Atg7 deletion in various tissues Sep 2016 A new CreERT2 line for studying PDGFRα-expressing cells in vivo Aug 2016 Monitoring cell replacemjat and migration in vivo with Kaede Jun 2016 Essjatial role of condjasins I and II for early embryonic divisions in mice May 2016 Impaired female fertility in Tinagl1 deficijat mice Apr 2016 Impaired female fertility in Tinagl1 deficijat mice Mar 2016 A knock-in mouse strain with R124H human TGFBI mutationC Feb 2016 Activation of NF-κB pathway and suppression of cell death through linear polyubiquitination activity of LUBAC Jan 2016 Tracking and depletion of XCR1-positive djadritic cells 2015 Dec 2015 Estimating germline mutation rate in laboratory mouse Nov 2015 Pathomechanistic model mice of sporadic ALS: Conditional ADAR2 knockout mice AR2 Oct 2015 A tool for olfactory sensory neuron-specific mosaic analysis Sep 2015 One-step generation of multiple transgenic mouse lines Aug 2015 Multiple roles of Tetraspanin-interacting protein IGSF8 Jul 2015 SIP1 expression patterns in the brain Jun 2015 Genetic tool for controlled G-CaMP7 expression in vivo May 2015 A key factor for epigenetic inheritance of DNA methylation Apr 2015 Mouse model of human 15q11–13 duplication Feb 2015 Sirt1 overexpression in neural and vascular endothelial cells Jan 2015 Clarifying the role of Fbxw7 in cancer 2014 Dec 2014 CXCL12-abundant reticular cells as a microenvironmental niche in bone marrow Nov 2014 C429S mutation in the mouse β-catenin gene leads to infertility Oct 2014 A model mouse strain for Dravet syndrome Sep 2014 App knock-in mouse strains: new models for Alzheimer’s disease Aug 2014 Cell signaling of stress response via ASK1 Jul 2014 Visualizing the neuronal activity-regulated gene Arc Jun 2014 Conditional ablation of HMGB1 in mice May 2014 Acquired A20 (Tnfaip3) deficiency in mice Apr 2014 Targeted disruption of exon 52 in the dystrophin gene Mar 2014 Novel ROSA26 Cre-reporter knock-in C57BL/6N mice Jan 2014 Fluorescent labeling of GABAergic neurons in the GAD67-GFP knock-in mouse 2013 Dec 2013 New reporter line for optogenetic stimulation at high frequencies Nov 2013 Skin abnormalities in mice lacking CD109 Oct 2013 Lymphotoxin signaling in thymic organogenesis Sep 2013 Altered barrier integrity and enhanced sensitization by filaggrin deficiency Aug 2013 Visualizing primordial germ cell development in mice Jul 2013 Cre-mediated recombination in villus epithelial cells of the intestine Jun 2013 A tool for the conditional deletion of the transcriptional repressor Bcl6 May 2013 Regulating gene expression in photoreceptor precursor cells Apr 2013 Expanding the repertoire of optogenetic control Mar 2013 Cre reporter mouse expressing nuclear-localized beta-galactosidase Feb 2013 Multifunctional Rosa26 reporter mouse strain Jan 2013 Monitoring endoplasmic reticulum stress in mice 2012 Dec 2012 CD169+ macrophages in immune regulation Nov 2012 Metabolic impact of glucagon deficiency Oct 2012 A tool for the generation of germline-competent iPS cells Sep 2012 Critical roles of TRAF6 Aug 2012 Lethal anemia and chronic polyarthritis caused by undigested mammalian DNA Jul 2012 PD-1 deficiency and autoimmunity Jun 2012 Atg7 deletion in various tissues May 2012 Renin-angiotensin system in hypertension Apr 2012 Nrf2 in stress response and cancer development Mar 2012 Autophagy monitoring congenic strains Feb 2012 Green congenic mouse strains Jan 2012 A gene for central respiratory regulation 2011 Dec 2011 Neurodegeneration via endoplasmic reticulum stress Nov 2011 Hairless Congenics for Dermatology Studies Oct 2011 Visualizing Histone H2A Variants in Chromatin Sep 2011 TRPM1, a causative molecule for night blindness in retinal ON bipolar cells Aug 2011 GP2 on M Cells for the Mucosal Immune Response Jul 2011 A Systemic Inflammation Model:Unc93B1 with a D34A mutation Jun 2011 A Dnmt1 knock-out mouse for epigenetic studies May 2011 Detecting Autophagy in the Heart Apr 2011 A Conditional Lung Injury Model Mar 2011 Visualizing neuronal activity 2010 Jul 2010 A model for retinitis pigmentosa (RP) Jun 2010 A model for psychiatric disorder 2009 Oct 2009 Dopamine receptor knockout mice Sep 2009 Sox2: An essential factor for maintaining neural stem cell Aug 2009 Visualizing the Wnt signal pathway Jul 2009 Atg5: An essential molecule of autophagy Jun 2009 C57BL/6-Ly5 Antigen (Ptprc) Congenic Strains May 2009 The only one strain for study of NF-kB/RelA subunit in vivo Apr 2009 A Japanese wild-derived inbred strain for functional genomics Mar 2009 Fucci mice for visualizing cell-cycle in vivo Feb 2009 The Tsix/Xist-deficient Strains Jan 2009 BALB/c Hbb Congenic Strains 2008 Aug 2008 Delphilin KO Mouse Jul 2008 Lck-p19Arf Transgenic Mouse Jun 2008 Drs KO Mouse May 2008 TH-GFP Transgenic Mouse Apr 2008 PRAT4A KO Mouse Mar 2008 Disc1 Mutant Mouse Feb 2008 T-bet Transgenic Mouse Jan 2008 mDomino KO Mouse 2007 Dec 2007 Nanog-GFP Transgenic Mouse Nov 2007 EGFP-Akt Transgenic Mouse Oct 2007 Dmp1-HBEGF Transgenic Mouse Sep 2007 Gdf5Rgsc451 Mouse Aug 2007 K14-AhR-CA transgenic mice Jul 2007 p38α floxed mouse Jun 2007 Card15/Nod2 KO mouse May 2007 Lefty & Noda Apr 2007 Kf-1 Knock-out Mouse Mar 2007 ERAI transgenic mouse Feb 2007 FLPe transgenic mouse Jan 2007 RECS1 knockout mouse 2006 Dec 2006 Mitfmi-bw mutant mouse Nov 2006 MFG-E8 KO mouse Oct 2006 p27 KO mouse Sep 2006 Thy1-SpH transgenic mouse Aug 2006 Semaphorin III/D gene targeting mice Jul 2006 Cre Transgenic Mouse Series_2 Jun 2006 Cre Transgenic Mouse Series_1 May 2006 A model for bipolar disorder Apr 2006 Heparin-binding EGF-like growth factor (HB-EGF)-deficient mouse Mar 2006 t(7;11)AML原因遺伝子NUP98-HOXA9 Feb 2006 Mesp1:心臓形成の決定因子初期中胚葉の形成機構解明のモデル Jan 2006 A Model for Hyperlipidemia SHL: Spontaneous Mutation in the Apolipoprotein E gene 2005 Dec 2005 A Model for Type 2 Hyper-IgM Syndrome Nov 2005 SMXA-RI Strains Oct 2005 Nrf2 & Keap1 Sep 2005 Visualization of Primordial Germ Cells in Vivo Jun 2005 Analysis of Rho/Rho-kinase singnaling pathway Jun 2005 A Model for Tumor Biology: p53 KO mouse May 2005 A Model for Impaired Cytokine Secretion Apr 2005 A Model for Congenital Alopecia Mar 2005 自己免疫性拡張型心筋症モデル Mar 2005 オートファジー検出GFPモデル Mar 2005 乳児型神経軸索ジストロフィー(INAD)モデル コメントは受け付けていません。
