BRC facility Health Report
Update information
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IMPC 遺伝子・表現型 検索







Cryopreservation of Mouse Embryos by Ethylene Glycol-Based Vitrification
JoVE 3155 11/18/2011


Mar 2020
パイロトーシス実行因子: ガスダーミンD
Feb 2020
In vivo イメージングに有用な新規ヘアレスマウス

hairless mouse

Dec 2019
Nov 2019
Oct 2019
Aug 2019
fig.201912 fig.201911 fig.201910

Jul 2019
Heat shock transcription factor 1 (HSF1)
Jun 2019
Apr 2019
Mar 2019
Long-sleep mouse model induced by Sik3 splice mutation
fig.201907 fig.201906 fig.201904 fig.201903
Feb 2019
iRFP transgenic mice for in vivo imaging
Jan 2019
Bcl6 reporter mice for immune memory research
fig.201902 fig.201901

Dec 2018
Bicistronic Insulin1-Cre knock-in mice
Nov 2018
Autism spectrum disorder (ASD) model mice
Oct 2018
Green-to-red fluorescent-convertible Cre-reporter mice
fig.201812 fig.201811 fig.A201810fig.B201810

Sep 2017
RAQP4, the main subset of the aquaporin water channel family in the brain
Aug 2017
Transcranial imaging of intracellular Ca2+ in astrocytes and neurons
Jun 2017
A tool for understanding endogenous sphingolipid synthesis
Apr 2017
Regulatory function of nuclear protein IκB-ζ in inflammatory responses
fig.201709 fig.201708-1 fig.201706 fig.201704
Mar 2017
Identifying pheromone circuits in mice
Feb 2017
Cell type-specific expression of photoconvertible fluorescent protein KikGR
fig.201703 fig.201702

Oct 2016
Autophagy monitoring congenic strains
Oct 2016
Atg7 deletion in various tissues
Sep 2016
A new CreERT2 line for studying
PDGFRα-expressing cells in vivo
Aug 2016
Monitoring cell replacement and migrationin vivo with Kaede
fig.201610_Autophagy Fig.201610_Atg7 fig.201609 fig.201608
Jun 2016
Essential role of condensins I and II for early embryonic divisions in mice
May 2016
Whole-body in vivo monitoring using human IL6-luciferase transgenic mice
Apr 2016
Impaired female fertility in Tinagl1 deficient mice
Mar 2016
A knock-in mouse strain with R124H human TGFBI mutation
fig.201606 fig.201605 fig.201604 fig.201503
Feb 2016
Activation of NF-κB pathway and suppression of cell death through linear polyubiquitination activity of LUBAC
Jan 2016
Tracking and depletion of XCR1-positive dendritic cells
fig.201602 fig.201601

Dec 2015
Estimating germline mutation rate in laboratory mouse
Nov 2015
Pathomechanistic model mice of sporadic ALS: Conditional ADAR2 knockout mice AR2
Oct 2015
A tool for olfactory sensory neuron-specific mosaic analysis
Sep 2015
One-step generation of multiple transgenic mouse lines
fig.201512 fig.201511 fig.201510 fig.201509
Aug 2015
Multiple roles of Tetraspanin-interacting protein IGSF8
Jul 2015
SIP1 expression patterns in the brain
Jun 2015
Genetic tool for controlled G-CaMP7 expression in vivo
May 2015
A key factor for epigenetic inheritance of DNA methylation
fig.201508 fig.201507 fig.201506

Apr 2015
Mouse model of human 15q11–13 duplication
Feb 2015
Sirt1 overexpression in neural and vascular endothelial cells
Jan 2015
Clarifying the role of Fbxw7 in cancer
fig.201504 fig.201502 fig.201501

Dec 2014
CXCL12-abundant reticular cells as a microenvironmental niche in bone marrow
Nov 2014
C429S mutation in the mouse β-catenin gene leads to infertility
Oct 2014
A model mouse strain for Dravet syndrome
Sep 2014
App knock-in mouse strains: new models for Alzheimer’s disease
fig.201412 fig.201411 fig.201410 fig.201409
Aug 2014
Cell signaling of stress response via ASK1
Jul 2014
Visualizing the neuronal activity-regulated gene Arc
Jun 2014
Conditional ablation of HMGB1 in mice
May 2014
Acquired A20 (Tnfaip3) deficiency in mice
fig.201408 fig.201407 fig.201406 fig.201405
Apr 2014
Targeted disruption of exon 52 in the dystrophin gene
Mar 2014
Novel ROSA26 Cre-reporter knock-in C57BL/6N mice
Jan 2014
Fluorescent labeling of GABAergic neurons in the GAD67-GFP knock-in mouse
fig.201404 fig.201403 fig.201401

Dec 2013
New reporter line for optogenetic stimulation at high frequencies
Nov 2013
Skin abnormalities in mice lacking CD109
Oct 2013
Lymphotoxin signaling in thymic organogenesis
Sep 2013
Altered barrier integrity and enhanced sensitization by filaggrin deficiency
fig.201312 fig.201311 fig.201310 fig.201309
Aug 2013
Visualizing primordial germ cell development in mice
Jul 2013
Cre-mediated recombination in villus epithelial cells of the intestine
Jun 2013
A tool for the conditional deletion of the transcriptional repressor Bcl6
May 2013
Regulating gene expression in photoreceptor precursor cells
fig.201308 fig.201307 fig.201306 fig.201305
Apr 2013
Expanding the re
pertoire of optogenetic control
Mar 2013
Cre reporter mouse expressing nuclear-localized beta-galactosidase
Feb 2013
Multifunctional Rosa26 reporter mouse strain
 Jan 2013
Monitoring endoplasmic reticulum stress in mice
fig.201304  fig.201303  fig.201302  fig.201301

Dec 2012
CD169+ macrophages in immune regulation
Nov 2012
Metabolic impact of glucagon deficiency
Oct 2012
A tool for the generation of germline-competent iPS cells
Sep 2012
Critical roles of TRAF6
fig.201212 fig.201211 fig.201210 fig.201209
Aug 2012
Lethal anemia and chronic polyarthritis caused by undigested mammalian DNA
Jul 2012
PD-1 deficiency and autoimmunity
Jun 2012
Atg7 deletion in various tissues
May 2012
Renin-angiotensin system in hypertension
fig.201208 fig.201207 fig.201206 fig.201205
Apr 2012
Nrf2 in stress response and cancer development
Mar 2012
Autophagy monitoring congenic strains
Feb 2012
Green congenic mouse strains
Jan 2012
A gene for central respiratory regulation
fig.201204 fig.201203 fig.201202 fig.201201

Dec 2011
Neurodegeneration via endoplasmic reticulum stress
Nov 2011
Hairless Congenics for Dermatology Studies
Oct 2011
Visualizing Histone H2A Variants in Chromatin
Sep 2011
TRPM1, a causative molecule for night blindness in retinal ON bipolar cells
fig.201112 fig.201111 fig.201110 fig.201109
Aug 2011
GP2 on M Cells for the Mucosal Immune Response
Jul 2011
A Systemic Inflammation Model:Unc93B1 with a D34A mutation
Jun 2011
A Dnmt1 knock-out mouse for epigenetic studies
May 2011
Detecting Autophagy in the Heart
fig.201108 fig.201107 fig.201106 fig.201105
Apr 2011
A Conditional Lung Injury Model
Mar 2011
Visualizing neuronal activity
fig.201104 fig.201103

Jul 2010
A model for retinitis pigmentosa (RP)
Jun 2010
A model for psychiatric disorder
fig.201007 fig.201006

Oct 2009
Dopamine receptor knockout mice
Sep 2009
Sox2: An essential factor for maintaining neural stem cell
Aug 2009
Visualizing the Wnt signal pathway

Jul 2009
Atg5: An essential molecule of autophagy
Jun 2009
C57BL/6-Ly5 Antigen (Ptprc) Congenic Strains
May 2009
The only one strain for study of NF-kB/RelA subunit in vivo
Apr 2009
A Japanese wild-derived inbred strain for functional genomics
Mar 2009
Fucci mice for visualizing cell-cycle in vivo
Feb 2009
The Tsix/Xist-deficient Strains
Jan 2009
BALB/c Hbb Congenic Strains

Aug 2008
Delphilin KO Mouse
Jul 2008
Lck-p19Arf Transgenic Mouse
Jun 2008
Drs KO Mouse
May 2008
TH-GFP Transgenic Mouse
fig.200808 fig.200807 fig.200806 fig.200805
Apr 2008
Mar 2008
Disc1 Mutant Mouse
Feb 2008
T-bet Transgenic Mouse
Jan 2008
mDomino KO Mouse
fig.200804 fig.200803 fig.200802 fig.200801-1fig.200801-2

Dec 2007
Nanog-GFP Transgenic Mouse fig.200712
Nov 2007
EGFP-Akt Transgenic Mouse fig.200711
Oct 2007
Dmp1-HBEGF Transgenic Mouse
Sep 2007
Gdf5Rgsc451 Mouse fig.200709
Aug 2007
K14-AhR-CA transgenic mice fig.200708
Jul 2007
p38α floxed mouse fig.200707
Jun 2007
Card15/Nod2 KO mouse fig.200706
May 2007
Lefty & Noda fig.200705
Apr 2007
Kf-1 Knock-out Mouse fig.200704
Mar 2007
ERAI transgenic mouse fig.200703
Feb 2007
FLPe transgenic mouse fig.200702
Jan 2007
RECS1 knockout mouse fig.200701

Dec 2006
Mitfmi-bw mutant mouse fig.200612
Nov 2006
MFG-E8 KO mouse fig.200611
Oct 2006
p27 KO mouse fig.200610
Sep 2006
Thy1-SpH transgenic mouse
Aug 2006
Semaphorin III/D gene targeting mice fig.200608
Jul 2006
Cre Transgenic Mouse Series_2 fig.200607
Jun 2006
Cre Transgenic Mouse Series_1 fig.200606-1fig.201606-2fig.201606-3
May 2006
A model for bipolar disorder fig.200605
Apr 2006
Heparin-binding EGF-like growth factor (HB-EGF)-deficient mouse fig.200604
Mar 2006
t(7;11)AML原因遺伝子NUP98-HOXA9 fig.200603
Feb 2006
Mesp1:心臓形成の決定因子初期中胚葉の形成機構解明のモデル fig.200602
Jan 2006
A Model for Hyperlipidemia SHL: Spontaneous Mutation in the Apolipoprotein E gene 200601

Dec 2005
A Model for Type 2 Hyper-IgM Syndrome fig.200512
Nov 2005
SMXA-RI Strains fig.200511-1fig.200511-2
Oct 2005
Nrf2 & Keap1
Sep 2005
Visualization of Primordial Germ Cells in Vivo fig.200509
Jun 2005
Analysis of Rho/Rho-kinase singnaling pathway fig.200506_Rho
Jun 2005
A Model for Tumor Biology: p53 KO mouse fig.200506_p53KO
May 2005
A Model for Impaired Cytokine Secretion fig.200505
Apr 2005
A Model for Congenital Alopecia fig.200504
Mar 2005
自己免疫性拡張型心筋症モデル 200503Pdcd1
Mar 2005
オートファジー検出GFPモデル 200503GFP
Mar 2005
乳児型神経軸索ジストロフィー(INAD)モデル 200503INAD