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今月のマウス・バックナンバー

2025

Apr 2025
Recql5 遺伝子変異マウスを用いた染色体断片化後再合成の誘発

2024

Dec 2024
生体内タンパク質間相互作用を解析可能なin vivo BioIDマウス

Apr 2024
CD103陽性樹状細胞と消化管粘膜免疫寛容の関係性

Mar 2024
新規プローブを用いた、神経細胞におけるホモフィリック相互作用の可視化

Jan 2024
エメラルドルシフェラーゼを発現する新規発光Tgマウス

2023

Oct 2023
時計遺伝子Bmal1の転写リズム制御メカニズム

Sep 2023
オキシトシン受容体(OXTR)機能解析ツール

July 2023
着床前胚での性別判定を可能にする蛍光レポーターマウス

May 2023
新規カルシウムセンサーG-CaMP9aによる神経活動in vivoイメージング

Feb 2023
Gal4/UAS発現システム依存的な遺伝子組み換えと細胞イメージングが可能なマウス

Jan 2023
B細胞で発現する
Creドライバーマウス

2022

Nov 2022
RASopathies(RAS/MAPK症候群)モデルマウス

Oct 2022
生殖細胞系列で発現するCreドライバーマウス

Aug 2022
オキシトシン産生ニューロンCreドライバーマウス

Jun 2022
がん研究注目の因子Meflin(Islr)機能解析ツール

Apr 2022
重複せずに三胚葉を蛍光標識可能なTRiCKマウス

Mar 2022
時空間特異的遺伝子組み換えを可能にする新規Creドライバーマウス

Feb 2022
新規タンパク質ノックダウン技術オーキシンデグロン(AID) 2法

2021

Nov 2021
3.0-Mb欠失を再現した22q11.2欠失症候群モデルマウス

Oct 2021
新規白質消失病モデルtoyマウス

Sep 2021
マウスでの冬眠様状態の誘導

Aug 2021
内耳特異的にGata3遺伝子の発現を制御するエンハンサー配列Gata3 OVE

May 2021
効率的なゲノム編集マウス作製実現のため開発されたCas9 Tgマウス

Mar 2021
染色体工学技術を用いて作製された新規ダウン症候群モデルマウス

Feb 2021
Ucp1 in vivoイメージングマウス

2020

Dec 2020
光変換により細胞動態をモニター可能なKaedeマウス

Nov 2020
自然免疫応答を制御する転写因子：IRF3

Mar 2020
パイロトーシス実行因子: ガスダーミンD

Feb 2020
In vivo イメージングに有用な新規ヘアレスマウス

2019

Dec 2019
グリシン作動性ニューロンCreドライバーマウス

Nov 2019
ENUミュータジェネシスによって樹立されたGLUT1欠損症モデルマウス

Oct 2019
特定ゲノム領域上の分子間相互作用解析に有用な3xFLAG-dCas9発現マウス

Aug 2019
造血幹細胞の自己複製を制御するPHF6

Jul 2019
熱ストレス応答だけでない、様々な場面で機能する転写因子
Heat shock transcription factor 1 (HSF1)

Jun 2019
血友病Bモデルマウス

Apr 2019
痛覚異常を示すZfhx2遺伝子欠損マウス

Mar 2019
Long-sleep mouse model induced by Sik3 splice mutation

Feb 2019
iRFP transgenic mice for in vivo imaging

Jan 2019
Bcl6 reporter mice for immune memory research

2018

Dec 2018
Bicistronic Insulin1-Cre knock-in mice

Nov 2018
Autism spectrum disorder (ASD) model mice

Oct 2018
Green-to-red fluorescent-convertible Cre-reporter mice

2017

Sep 2017
RAQP4, the main subset of the aquaporin water channel family in the brain

Aug 2017
Transcranial imaging of intracellular Ca2+ in astrocytes and neurons

Jun 2017
A tool for understanding endogenous sphingolipid synthesis

Apr 2017
Regulatory function of nuclear protein IκB-ζ in inflammatory responses

Mar 2017
Identifying pheromone circuits in mice

Feb 2017
Cell type-specific expression of photoconvertible fluorescent protein KikGR

2016

Oct 2016
Autophagy monitoring congjaic strains

Oct 2016
Atg7 deletion in various tissues

Sep 2016
A new CreERT2 line for studying PDGFRα-expressing cells in vivo

Aug 2016
Monitoring cell replacemjat and migration in vivo with Kaede

Jun 2016
Essjatial role of condjasins I and II for early embryonic divisions in mice

May 2016
Impaired female fertility in Tinagl1 deficijat mice

Apr 2016
Impaired female fertility in Tinagl1 deficijat mice

Mar 2016
A knock-in mouse strain with R124H human TGFBI mutationC

Feb 2016
Activation of NF-κB pathway and suppression of cell death through linear polyubiquitination activity of LUBAC

Jan 2016
Tracking and depletion of XCR1-positive djadritic cells

2015

Dec 2015
Estimating germline mutation rate in laboratory mouse

Nov 2015
Pathomechanistic model mice of sporadic ALS: Conditional ADAR2 knockout mice AR2

Oct 2015
A tool for olfactory sensory neuron-specific mosaic analysis

Sep 2015
One-step generation of multiple transgenic mouse lines

Aug 2015
Multiple roles of Tetraspanin-interacting protein IGSF8

Jul 2015
SIP1 expression patterns in the brain

Jun 2015
Genetic tool for controlled G-CaMP7 expression in vivo

May 2015
A key factor for epigenetic inheritance of DNA methylation

Apr 2015
Mouse model of human 15q11–13 duplication

Feb 2015
Sirt1 overexpression in neural and vascular endothelial cells

Jan 2015
Clarifying the role of Fbxw7 in cancer

2014

Dec 2014
CXCL12-abundant reticular cells as a microenvironmental niche in bone marrow

Nov 2014
C429S mutation in the mouse β-catenin gene leads to infertility

Oct 2014
A model mouse strain for Dravet syndrome

Sep 2014
App knock-in mouse strains: new models for Alzheimer’s disease

Aug 2014
Cell signaling of stress response via ASK1

Jul 2014
Visualizing the neuronal activity-regulated gene Arc

Jun 2014
Conditional ablation of HMGB1 in mice

May 2014
Acquired A20 (Tnfaip3) deficiency in mice

Apr 2014
Targeted disruption of exon 52 in the dystrophin gene

Mar 2014
Novel ROSA26 Cre-reporter knock-in C57BL/6N mice

Jan 2014
Fluorescent labeling of GABAergic neurons in the GAD67-GFP knock-in mouse

2013

Dec 2013
New reporter line for optogenetic stimulation at high frequencies

Nov 2013
Skin abnormalities in mice lacking CD109

Oct 2013
Lymphotoxin signaling in thymic organogenesis

Sep 2013
Altered barrier integrity and enhanced sensitization by filaggrin deficiency

Aug 2013
Visualizing primordial germ cell development in mice

Jul 2013
Cre-mediated recombination in villus epithelial cells of the intestine

Jun 2013
A tool for the conditional deletion of the transcriptional repressor Bcl6

May 2013
Regulating gene expression in photoreceptor precursor cells

Apr 2013
Expanding the repertoire of optogenetic control

Mar 2013
Cre reporter mouse expressing nuclear-localized beta-galactosidase

Feb 2013
Multifunctional Rosa26 reporter mouse strain

Jan 2013
Monitoring endoplasmic reticulum stress in mice

2012

Dec 2012
CD169+ macrophages in immune regulation

Nov 2012
Metabolic impact of glucagon deficiency

Oct 2012
A tool for the generation of germline-competent iPS cells

Sep 2012
Critical roles of TRAF6

Aug 2012
Lethal anemia and chronic polyarthritis caused by undigested mammalian DNA

Jul 2012
PD-1 deficiency and autoimmunity

Jun 2012
Atg7 deletion in various tissues

May 2012
Renin-angiotensin system in hypertension

Apr 2012
Nrf2 in stress response and cancer development

Mar 2012
Autophagy monitoring congenic strains

Feb 2012
Green congenic mouse strains

Jan 2012
A gene for central respiratory regulation

2011

Dec 2011
Neurodegeneration via endoplasmic reticulum stress

Nov 2011
Hairless Congenics for Dermatology Studies

Oct 2011
Visualizing Histone H2A Variants in Chromatin

Sep 2011
TRPM1, a causative molecule for night blindness in retinal ON bipolar cells

Aug 2011
GP2 on M Cells for the Mucosal Immune Response

Jul 2011
A Systemic Inflammation Model:Unc93B1 with a D34A mutation

Jun 2011
A Dnmt1 knock-out mouse for epigenetic studies

May 2011
Detecting Autophagy in the Heart

Apr 2011
A Conditional Lung Injury Model

Mar 2011
Visualizing neuronal activity

2010
Jul 2010
A model for retinitis pigmentosa (RP)		 Jun 2010
A model for psychiatric disorder

2009
Oct 2009
Dopamine receptor knockout mice 		Sep 2009
Sox2: An essential factor for maintaining neural stem cell 		Aug 2009
Visualizing the Wnt signal pathway
 Jul 2009
Atg5: An essential molecule of autophagy
Jun 2009
C57BL/6-Ly5 Antigen (Ptprc) Congenic Strains 		May 2009
The only one strain for study of NF-kB/RelA subunit in vivo 		Apr 2009
A Japanese wild-derived inbred strain for functional genomics 		Mar 2009
Fucci mice for visualizing cell-cycle in vivo
Feb 2009
The Tsix/Xist-deficient Strains 		Jan 2009
BALB/c Hbb Congenic Strains

2008
Aug 2008
Delphilin KO Mouse		 Jul 2008
Lck-p19Arf Transgenic Mouse		 Jun 2008
Drs KO Mouse		 May 2008
TH-GFP Transgenic Mouse
Apr 2008
PRAT4A KO Mouse		 Mar 2008
Disc1 Mutant Mouse		 Feb 2008
T-bet Transgenic Mouse		 Jan 2008
mDomino KO Mouse

2007
Dec 2007
Nanog-GFP Transgenic Mouse 		Nov 2007
EGFP-Akt Transgenic Mouse 		Oct 2007
Dmp1-HBEGF Transgenic Mouse
 Sep 2007
Gdf5Rgsc451 Mouse
Aug 2007
K14-AhR-CA transgenic mice 		Jul 2007
p38α floxed mouse 		Jun 2007
Card15/Nod2 KO mouse 		May 2007
Lefty & Noda
Apr 2007
Kf-1 Knock-out Mouse 		Mar 2007
ERAI transgenic mouse 		Feb 2007
FLPe transgenic mouse 		Jan 2007
RECS1 knockout mouse

2006
Dec 2006
Mitfmi-bw mutant mouse 		Nov 2006
MFG-E8 KO mouse 		Oct 2006
p27 KO mouse 		Sep 2006
Thy1-SpH transgenic mouse
Aug 2006
Semaphorin III/D gene targeting mice 		Jul 2006
Cre Transgenic Mouse Series_2 		Jun 2006
Cre Transgenic Mouse Series_1 		May 2006
A model for bipolar disorder
Apr 2006
Heparin-binding EGF-like growth factor (HB-EGF)-deficient mouse 		Mar 2006
t(7;11)AML原因遺伝子NUP98-HOXA9 		Feb 2006
Mesp1:心臓形成の決定因子初期中胚葉の形成機構解明のモデル 		Jan 2006
A Model for Hyperlipidemia SHL: Spontaneous Mutation in the Apolipoprotein E gene

2005
Dec 2005
A Model for Type 2 Hyper-IgM Syndrome 		Nov 2005
SMXA-RI Strains 		Oct 2005
Nrf2 & Keap1
 Sep 2005
Visualization of Primordial Germ Cells in Vivo
Jun 2005
Analysis of Rho/Rho-kinase singnaling pathway 		Jun 2005
A Model for Tumor Biology: p53 KO mouse 		May 2005
A Model for Impaired Cytokine Secretion 		Apr 2005
A Model for Congenital Alopecia
Mar 2005
自己免疫性拡張型心筋症モデル
 Mar 2005
オートファジー検出GFPモデル
 Mar 2005
乳児型神経軸索ジストロフィー(INAD)モデル


 

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